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Publication scientifique




Publié le 21 mars 2018


  • Gallois N., Alpha-Bazin B., Ortet P., Barakat M., Piette L., Long J., Berthomieu C., Armengaud J., Chapon V. (2017), Proteogenomic insights into uranium tolerance of a Chernobyl's Microbacterium bacterial isolateJ. Proteomics, 177, 148-157.1.
  • Paredes E., Avazeri E., Malard V., Vidaud C., Ortega R., Nonell A., Isnard H., Chartier F., Bresson C. (2018) A New Procedure for High Precision Isotope Ratio Determinations of U, Cu and Zn at Nanogram Levels in Cultured Human Cells: What Are the Limiting Factors?, Talanta, 178, 894-904.


  • Sauge-Merle S., Brulfert F., Pardoux R., Solari P.L., Lemaire D., Safi S., Guilbaud P., Simoni E., Merroun M.L., Berthomieu C. (2017) Structural Analysis of Uranyl Complexation by the EF-Hand Motif of Calmodulin: Effect of Phosphorylation. Chemistry – A European Journal, 23, 15505–15517. http://dx.doi.org/10.1002/chem.201703484.
  • Theodorakopoulos N., Février L., Barakat M., Ortet P., Christen R., Piette L., Levchuk S., Beaugelin-Seiller K., Sergeant C., Berthomieu C., Chapon V. (2017) Soil Prokaryotic Communities in Chernobyl Waste Disposal Trench T22 Are Modulated by Organic Matter and Radionuclide Contamination. FEMS microbiology ecology. http://dx.doi.org/10.1093/femsec/fix079.
  • Ortet P., Gallois N., Piette L., Long J., Berthomieu C., Armengaud J., Barakat M., Chapon V. (2017) Draft Genome Sequence of Microbacterium Oleivorans Strain A9, a Bacterium Isolated from Chernobyl Radionuclide-Contaminated Soil. Genome Announcements, 5. http://dx.doi.org/10.1128/genomeA.00092-17.
  • Brulfert F., Safi S., Jeanson A., Foerstendorf H., Weiss S., Berthomieu C., Sauge-Merle S., and Simoni É. (2017). Enzymatic activity of the CaM-PDE1 system upon addition of actinyl ions. J. Inorg. Biochem. 172, 46–54. doi:10.1016/j.jinorgbio.2017.04.007
  • Sauge-Merle S., Lemaire D., Evans R. W., Berthomieu C., Aupiais,J. (2017). Revisiting binding of plutonium to transferrin by CE-ICP-MS. Dalton Transactions, 46(5), 1389‑1396. https://doi.org/10.1039/C6DT04336D


  • Paredes E., Avazeri E., Malard V., Vidaud C., Reiller P.E., Ortega R., Nonell A., Isnard H., Chartier F., Bresson C. (2016) Evidence of isotopic fractionation of natural uranium in cultured human cells. Proc. Natl. Acad. Sci. U.S.A. 113, 14007–14012. doi:10.1073/pnas.1610885113
  • Brulfert F., Safi S., Jeanson A., Martinez-Baez E., Roques J., Berthomieu C., Solari P.-L., Sauge-Merle S., Simoni É. (2016) Structural Environment and Stability of the Complexes Formed Between Calmodulin and Actinyl Ions. Inorg. Chem., 55(6), 2728-2736. doi:10.1021/acs.inorgchem.5b02440
  • Darrouzet E., Graslin F., Marcellin D., Tcheremisinova I., Marchetti C., Salleron L., Pognonec P., Pourcher T. (2016) A systematic evaluation of sorting motifs in the sodium/iodide symporter (NIS). Biochem. J., 473(7), 919-928. doi:10.1042/BJ20151086
  • Duval S., Santini J.M., Lemaire D., Chaspoul F., Russell M.J., Grimaldi S., Nitschke W., Schoepp-Cothenet B. (2016) The H-Bond Network Surrounding the Pyranopterins Modulates Redox Cooperativity in the Molybdenum-bisPGD Cofactor in Arsenite Oxidase. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1857, 1353–1362. http://dx.doi.org/10.1016/j.bbabio.2016.05.003.
  • Ghssein G., Brutesco C., Ouerdane L., Fojcik C., Izaute A., Wang S., Hajjar C., Lobinski R., Lemaire D., Richaud P., Voulhoux R., Espaillat A., Cava F., Pignol D., Borezée-Durant E., Arnoux P. (2016) Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus. Science 352, 1105–1109. doi:10.1126/science.aaf1018
  • Uboldi C., Orsière T., Darolles C., Aloin V., Tassistro V., George I., Malard V. (2016) Poorly soluble cobalt oxide particles trigger genotoxicity via multiple pathways. Part. Fibre Toxicol. 13, 1-15. doi:10.1186/s12989-016-0118-8​


  • Beccia MR, Sauge-Merle S, Lemaire D, Brémond N, Pardoux R, Blangy S, Guilbaud P, Berthomieu C (2015) Thermodynamics of Calcium binding to the Calmodulin N-terminal domain to evaluate site-specific affinity constants and cooperativity. J Biol Inorg Chem., 20(5), 905-19.
  • Bauvais C, Zirah S, Piette L, Chaspoul F, Domart-Coulon I, Chapon V, Gallice P, Rebuffat S, Pérez T, Bourguet-Kondracki ML. (2015) Sponging up metals: Bacteria associated with the marine sponge Spongia officinalis. Mar Environ Res., 104, 20-30.
  • Theodorakopoulos N, Chapon V, Coppin F, Floriani M, Vercouter T, Sergeant C, Camilleri V, Berthomieu C, Fevrier L (2014) Use of combined microscopic and spectroscopic techniques to reveal interactions between uranium and Microbacterium sp. strain A9, a strain isolated from the Chernobyl exclusion zone. J Hazardous Material, 285, 285-93.


  • Khemiri  A, Carriere M, Bremond N, Ben Mlouka  MA, Coquet  L, Llorens I, Chapon V, Jouenne T, Cosette P, Berthomieu C (2014) Escherichia coli response to uranyl exposure at low pH and associated protein regulations. PLoS One 9(2):e89863.
  • Dalla Bernardina S, Alabarse F,  Kalinko  A, Roy P, Vita N,  Hienerwadel  R, Berthomieu  C,  Judeinstein P,  Zanotti J-M, Bantignies JL,  Haines J,  Catafesta J, Creff G, Manceron L,  Brubach JB (2014) " New experimental set-ups for studying nanoconfined water on the AILES beamline at SOLEIL. " Vibrational Spectroscopy 75 : 154–161
  • Xerri B, Petitjean H, Dupeyrat F, Flament JP, Lorphelin A, Vidaud C, Berthomieu C, Berthomieu D (2014) Mid and far-IR marker bands of metal coordination sites of histidine side chains in a protein, Cu,Zn-Superoxide dismutase. Eur. J. Inorg. Chem. 4650-4659.​
  • Ludanyi M, Blanchard L, Dulermo R, Brandelet G, Bellanger L, Pignol D, Lemaire D, de Groot A. (2014) Radiation response in Deinococcus deserti: IrrE is a metalloprotease that cleaves repressor protein DdrO. Mol Microbiol. 94, 434-449.
  • Gresh N, El Hage K, Perahia D, Piquemal J-P, Berthomieu C,  Berthomieu D (2014) Polarizable Molecular Mechanics studies of Cu(I)/Zn(II) Superoxide Dismutase. Bimetallic binding site and structured waters. Journal of Computational Chemistry 35, 2096-2106.


Vulgarisation / Popularization​ ​:

Delangle P, Berthomieu C AVRIL 2014 • BIOFUTUR 353, 39-42. Mimer le vivant pour piéger les radionucléides



  • Mondani L, Piette L, Christen R, Bachar D, Berthomieu C, Chapon V. (2013) Microbacterium lemovicicum sp. nov., a bacterium isolated from natural uranium-rich soil. Int J Syst Evol Microbiol. 63, 2600-6.
  • Vita N, Brubach J-B, Hienerwadel R, Bremond N, Berthomieu D, Roy P, Berthomieu C (2013) Electrochemically-induced Far-InfraRed difference spectroscopy on metalloproteins using advanced synchrotron technology. Anal. Chem. 85(5):2891-2898.
  • Theodorakopoulos N, Bachar D, Christen R, Alain K, Chapon V (2013) Exploration of Deinococcus-Thermus molecular diversity by novel group-specific nested-PCR primers. MicrobiologyOpen, 2013 Oct; 2(5) : 862-872
  • Tremey E, Bonnot F, Moreau Y, Berthomieu C, Desbois A, Favaudon V, Blondin G, Houée-Levin C, Nivière V (2013) Hydrogen bonding to the cysteine ligand of superoxide reductase. Acid-base control of the reaction intermediates. J Biol Inorg Chem. 2013 Aug 6. 18(7):815-30


  • Llorens I, Untereiner G, Jaillard D, Gouget B, Chapon V, Carriere M (2012) Uranium Interaction with Two Multi-Resistant Environmental Bacteria: Cupriavidus metallidurans CH34 and Rhodopseudomonas palustris. PLoS One. 7(12):e51783.
  • Chapon V, Piette L, Vesvres MH, Coppin F, Le Marrec C, Christen R, Theodorakopoulos N, Février L, Levchuk S, Martin-Garin A, Berthomieu C, Sergeant C (2012) Microbial diversity in contaminated soils along the T22 trench of the Chernobyl experimental platform. Appl Geochem 27, 1375-1383
  • Eswaramoorthy S, Poulain S, Hienerwadel R, Bremond N, Sylvester MD, Zhang YB, Berthomieu C, Van Der Lelie D, Matin A (2012) Crystal structure of ChrR-A quinone reductase with the capacity to reduce chromate. PLoS ONE 7(4):e36017
  • Gendrin C, Contreras-Martel C, Bouillot S, Elsen S, Lemaire D, Skoufias DA, Huber P, Attree I, Dessen A (2012) Structural basis of cytotoxicity mediated by the Type III secretion toxin ExoU from Pseudomonas aeruginosa. PLoS Pathog 8(4):e1002637
  • Sauge-Merle S, Lecomte-Pradines C, Carrier P, Cuine S, Dubow M (2012) Heavy metal accumulation by recombinant mammalian metallothionein within Escherichia coli protects against elevated metal exposure. Chemosphere 88, 918-924
  • Pardoux R, Sauge-Merle S, Lemaire D, Delangle P, Guilloreau L, Adriano JM, Berthomieu C (2012) Modulating uranium binding affinity in engineered calmodulin EF-hand peptides : effect of phosphorylation. PLoS ONE 7(8) e41922.


  • Marboutin L, Petitjean H, Xerri B, Vita N, Dupeyrat F, Flament JP, Berthomieu D, Berthomieu C (2011) Profiling the active site of a cuproenzyme through its far-infrared fingerprint (680-50 cm-1) Angew. Chem.Int. Ed. 50, 8062-8066.
  • Mondani L, Benzerara K, Carrière M, Mamindy-Pajany Y, FEVRIER L, Marmier N, Achouak W, Nardoux P, Berthomieu C, Chapon V (2011) Influence of uranium on bacterial communities: a comparison of natural uranium-rich soils with controls,PLoS One 6(10) e25771