The methodological approaches of the Cancer Biology and Infection laboratory range from biochemical study of protein systems (either isolated or in macromolecular complex) to pathophysiological studies using overexpression or invalidation of genes of interest.
The Large Scale Biology laboratory brings together four teams (EDyP, Biomics, Gen&Chem and OdyCell) who have decided to implement broad strategies (Proteomics, RNA interference, gene, Chemogenomics) to decipher the mechanisms that govern major cellular functions.
The scientific project of the Chemistry and Biology of Metals laboratory, at the interface of chemistry and biology, is the study of the structure, activity and regulation of complex biological systems carrying and using metallic ions. The critical mass and scientific consistency of this entity dedicated to the study of the chemistry and biology of metals are unique, nationally and internationally.
The Pathophysiology of Cytoskeleton group is investigating microtubule effectors that affect microtubules dynamics or tubulin structure. The group characterizes such effectors at the molecular and cellular levels, and test their functional importance in animal models and assesses their involvement in human pathologies.
The Cell & Plant Physiology laboratory studies the dynamics of the plant cell. This research, conducted at both the molecular and cellular, is then placed in the context of the whole plant during its development and subjected to changing conditions of the environment. They aimed at a better understanding of cellular mechanisms, e.g. metabolic pathways or processes of cell division and morphogenesis.
With a workforce of 350 people and based on a set of modern technology platforms (proteomics, high throughput screening, imaging, animal ...), our institute coordinates research programs of several units under the supervision of CEA, University of Grenoble Alpes and other research organizations (CNRS, Inserm and Inra).
Biosciences and Biotechnology Institute of Grenoble - CEA-Grenoble Head of the Institute: Jérôme Garin38054 Grenoble cedex 09, FrancePhone: 04 38 78 45 01 Fax: 04 38 78 51 55
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.