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The results obtained by the Pathophysiology of Cytoskeleton
Groupat our institute show that epothilone D (a drug that stabilizes microtubules, CEA/Inserm patent), is able to restore synaptic function impaired in mice deficient in STOP protein, and has dramatic beneficial effects on their behavior.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.