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Identified mlecular targets of tyrosination


​Mammalian cells contain filamentous networks. Among them the microtubule network, consisting of tubes with a diameter of 30 nm and of variable length, of the order of one to several tens of micrometers. These tubes are assembled from a protein, tubulin. Microtubules have outstanding physicochemical properties, which confer a particular capacity for self-organization and motility. Researchers at the Pathophysiology of Cytoskeleton group identified molecular targets of the tubulin tyrosination mechanism whose disorders are involved in some cancerous process.

Published on 1 December 2006

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