Highlight | Cancer | Genetic diseases
The ALK1 receptor is no longer an orphan
One of the team in our institute has published that two proteins, BMP9 and BMP10, are ligands of a receptor whose mutations are responsible for a rare vascular disease, the Rendu-Osler disease.
Lamouille S, Mallet C, Feige JJ and Bailly S Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis.
David L, Mallet C, Mazerbourg S, Feige JJ and Bailly S Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) endothelial cells.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.