Highlight | Molecular mechanisms | Nuclear Toxicology
The findings of the researchers at the Laboratory of Metals in Chemistry and Biology support the hypothesis that cobalt inhibits the biosynthesis and/or repair of Fe-S clusters by competing directly with iron, and illustrate the importance of iron-sulphur cluster biogenesis in cells.
Ranquet C, Ollagnier de Choudens S, Loiseau L, Barras F and Fontecave M
Cobalt stress in Escherichia coli: The effect on the iron-sulfur proteins.
Journal of Biological Chemistry, 2007
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.