Highlight | Cytoskeleton | Neurodegenerative diseases
The polyglutamylases are enzymes that add the side chains of glutamic acids to proteins after their synthesis in the cell. In collaboration with other laboratories, researchers at the Pathophysiology of Cytoskeleton group have discovered the enzyme family that removes these proteins modifications. Their work also highlight the essential role of the polyglutamylation of microtubules tubulin in neuronal survival and thus improve the understanding of many neurodegenerative diseases.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.