Interdisciplinary Research Institute of Grenoble (IRIG) - Other news https://irig.cea.fr/drf/irig/english/Pages/News/FM_Sante.aspx en-US https://irig.cea.fr/drf/irig/PublishingImages/min_Logo_IRIG_2023.jpg Interdisciplinary Research Institute of Grenoble (IRIG) - Other news https://irig.cea.fr/drf/irig/english Organoids vascularised in vitro: a remarkable advance https://www.cea.fr/drf/irig/english/Pages/News/Press-releases/2024_Xavier-Gidrol.aspx Journalists ; Researchers BGE Highlight ; Scientific result organoids on chip;organoids;personalized medicine; Wed, 28 Feb 2024 11:00:00 GMT PEPR MED-OOC explores organoids on chip https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2024/24_PEPR-MED-OOC.aspx Journalists ; Researchers BGE Highlight organoids on chip;personalized medicine;organoids;financial;PEPR; Mon, 26 Feb 2024 11:00:00 GMT The haploinsufficiency model of Rendu-Osler disease revisited https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2024/24_Sabine-Bailly.aspx Journalists ; Researchers Biosanté Highlight ; Scientific result Rendu-Osler; Tue, 20 Feb 2024 11:00:00 GMT Skin organoids to study Monkeypox https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2024/24_Karine-Raymond-Lebrin.aspx Journalists ; Researchers BGE Highlight ; Scientific result skin organoids;organoids;infectiology; Mon, 27 Nov 2023 11:00:00 GMT Tumoroids for personalized anti-tumor treatments https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2023/23_Odile-Filhol-Cochet.aspx Journalists ; Researchers Biosanté Highlight ; Scientific result tumoroid;kidney cancer;personalized medicine; Tue, 07 Nov 2023 11:00:00 GMT New compact modular nano-resonator mass spectrometer https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2023/23_Christophe-Masselon.aspx Journalists ; Researchers BGE Highlight ; Scientific result Nems;Mass spectrometry; Fri, 27 Oct 2023 10:00:00 GMT Tamoxifen activated CreERT2 recombinase is toxic for young mice https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2023/22_Claire-Bouvard.aspx Journalists ; Researchers Biosanté Highlight ; Scientific result Genetics; Tue, 29 Aug 2023 10:00:00 GMT Pr Walid Rachidi receives an endowment of nearly €60,000 from the association « Jetons le cancer » https://www.cea.fr/drf/irig/english/Pages/News/Awards/2023_Walid-Rachidi.aspx Cancer general public ; Journalists ; Researchers BGE Prizes and awards skin organoids;organoids;skin cancer; Mon, 26 Jun 2023 10:00:00 GMT Using genetics to identify kidney cancers most at risk https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2023/21_Laurent-Guyon.aspx Journalists ; Researchers Biosanté Highlight kidney cancer;COL7A1;Biomarkers; Mon, 19 Jun 2023 10:00:00 GMT Deregulation of autophagy alters tumor progression https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2023/21_Xavier-Gidrol.aspx Journalists ; Researchers BGE Highlight autophagy;transcriptomics; Mon, 19 Jun 2023 10:00:00 GMT Flora CLEMENT - Winner of the Junior Researcher Prize of the Espoir Isère association against cancer https://www.cea.fr/drf/irig/english/Pages/News/Awards/2023_Flora-Clement.aspx Cancer Journalists ; general public ; Researchers BGE Prizes and awards pancreas;pancreatic cancer;Cancer; Tue, 06 Jun 2023 10:00:00 GMT NLRP7 protein disguises placental cancer from the mother https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2023/20_Nadia-Alfaidy.aspx Cancer Researchers DS Highlight immune response;pregnancy;Choriocarcinoma;NLRP7; Thu, 23 Mar 2023 11:00:00 GMT Study of a fly protein point out towards a non-catalytic role for the RNA methyltransferase PCIF1 in gene expression https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2023/20_Marie-Odile-Fauvarque.aspx Researchers BGE Highlight PCIF1;transcription factor;epigenetics; Tue, 21 Mar 2023 11:00:00 GMT A big step towards the automation of cell biology tests using biomaterials https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2022/CNRS_Catherine_Picart.aspx Researchers DS Highlight BRM;biomaterial; Thu, 29 Sep 2022 10:00:00 GMT Proteogenomics: On the correct use of databases https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2022/18_Thomas-Burger.aspx Proteomics Researchers DS Highlight proteogenimics;genomics;proteomics;transcriptomics;BGE; Mon, 19 Sep 2022 10:00:00 GMT In vitro platform mimics the tumor microenvironment of pancreatic cancer https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2022/17_Catherine-Picart.aspx Cancer ; Biotechnology Researchers ; Companies DS Highlight Cancer;pancreas;biomimetic film;biomaterial; Fri, 06 May 2022 10:00:00 GMT A polysaccharide acts as a molecular gag of the pro-tumor endosulfatase HSulf-2 https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2022/17_Vives+Filhol.aspx Structural biology ; Cancer Researchers DS Highlight Thu, 05 May 2022 10:00:00 GMT Biomimetic film of controlled stiffness to study protein bioactivity toward human cells https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2022/CNRS_Catherine-Picart.aspx Researchers DS Highlight BRM;biomaterial; Wed, 09 Mar 2022 11:00:00 GMT Measurement of insulin production in a single pancreatic islet using a microfluidic chip https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2022/16_Xavier-Gidrol.aspx BGE Highlight insulin;microfluidics;organ-on-chip;organoids; Fri, 04 Mar 2022 11:00:00 GMT How does NLRP7 protein contribute to placental tumor cell camouflage? https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2021/15_Nadia-Alfaidy.aspx Cancer Researchers DS Highlight NLRP7;Choriocarcinoma;pregnancy;immune response; Thu, 16 Dec 2021 11:00:00 GMT A bacterial toxin guided by a human protein https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2021/14_Philippe-Huber.aspx Bacteria ; Cellular mechanisms Researchers BGE Highlight SST3;nosocomiale;injectisome;Pseudomonas;ExoU;virulence factor;virulence mechanisms; Wed, 07 Jul 2021 10:00:00 GMT Well Plate Maker: A user-friendly app to limit batch effects in large-scale biomedical studies https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2021/13_Thomas-Burger.aspx Large-scale biology ; Bioinformatic Researchers DS Highlight bioinformatique; Fri, 30 Apr 2021 10:00:00 GMT Three-dimensional architectures of phytoplankton for energy metabolism https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2021/13_Giovanni-Finazzi.aspx Cell and molecular imaging Researchers IBS Highlight 3D imaging;phytoplankton;cell and molecular imaging;mixotrophy; Tue, 20 Apr 2021 10:00:00 GMT Kidney cancer: Two targets for one therapy https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2021/12_Odile-Filhol-Cochet.aspx Cancer ; Large-scale biology Researchers ; Companies DS Highlight CK2;chemogenomics;kidney cancer;Patent;Cancer; Tue, 09 Mar 2021 11:00:00 GMT Discovery of a new biological rhythm https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2020/11_Lamya-Ghenim.aspx Cellular mechanisms ; Cell and molecular imaging Researchers ; Journalists ; general public BGE Highlight proteasome;ubiquitin;Lensless imaging;ultradian; Mon, 07 Dec 2020 11:00:00 GMT A new resistance strategy in pathogenic bacteria https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2020/11_Francois-Cretin.aspx Bacteria Researchers BCI Highlight Pseudomonas;nosocomiale; Fri, 27 Nov 2020 11:00:00 GMT Ménage à trois to control cell development https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2020/10_Emmanuel-Taillebourg.aspx Researchers DS Highlight ubiquitination;Drosophila;USP36;MYC;ubiquitin; Wed, 09 Sep 2020 10:00:00 GMT A circulating microRNA predictive of adrenocortical carcinoma recurrence https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2020/10_Nadia-Cherradi.aspx Cancer ; Biomarkers Researchers ; Journalists BCI Highlight miR-483-5p;miRNA;adrenocorticol carcinoma; Wed, 09 Sep 2020 10:00:00 GMT miRViz: Viewing and analyzing microRNA data https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2020/09_Laurent-Guyon.aspx Researchers BCI Highlight miRNA; Fri, 15 May 2020 10:00:00 GMT Multi-omics for understanding the regulation of gene expression https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2020/09_Delphine-Plfieger.aspx Epigenetics Researchers BCI Highlight histone;epigetetics; Sun, 19 Apr 2020 10:00:00 GMT MAP6, a neuronal protein in the lumen of microtubules https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2020/09_Annie-Andrieux.aspx Cytoskeleton Researchers DS Highlight MAP6;Microtubules;Map;neurones;cytoskeleton; Sat, 04 Apr 2020 10:00:00 GMT Plasticity of gene regulatory networks in Pseudomonas https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2020/08_Sylvie-Elsen.aspx Researchers DS Highlight Pseudomonas;ExlBA;exolysin A;transcription factor;virulence factors; Tue, 28 Jan 2020 11:00:00 GMT ProteoRE, a web application for the discovery of biomarkers of diagnostic interest https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2019/07_Yves-Vandenbrouck.aspx Proteomics ; Bioinformatic ; Biomarkers Researchers BGE Highlight biomarker;bioinformatics; Wed, 20 Nov 2019 11:00:00 GMT A new weapon to counter antibiotic resistance https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2019/07_Victor-Duarte.aspx Antibiotics Researchers DS Highlight Antibiotic;Antibiotic Resistance;Radical SAM; Mon, 28 Oct 2019 11:00:00 GMT Who protects the vascular endothelium of the liver from defenestration? https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2019/07_Jean-Jacques-Feige.aspx Researchers BCI Highlight BMP9;fibrosis;BMP; Fri, 11 Oct 2019 10:00:00 GMT A multi-target strategy to inhibit tumour progression https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2019/05_Nadia-Cherradi.aspx Cancer Researchers BCI Highlight Tis11B;Cancer; Fri, 30 Aug 2019 10:00:00 GMT Unintentional p-value hacking. The risk of making the data lie, despite themselves https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2019/06_Thomas-Burger.aspx Proteomics Researchers IRIG Highlight Wed, 28 Aug 2019 10:00:00 GMT Towards a better understanding of the regulation of chloroplast biogenesis and functions https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2019/04_Norbert-Rolland.aspx Researchers BGE Highlight chloroplast;plant proteome; Tue, 09 Jul 2019 10:00:00 GMT Novel therapeutic targets for prostate cancer https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2019/04_Xavier-Gidrol.aspx Cancer Researchers DS Highlight miRNA;prostate cancer; Tue, 09 Jul 2019 10:00:00 GMT Inflammasome and intrauterine growth retardation https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2019/03-Nadia-Cherradi.aspx IRIG Highlight IUGR;pregnancy; Tue, 21 May 2019 10:00:00 GMT At the heart of an intracellular symbiosis https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2019/02_Marie-Odile-Fauvarque.aspx Researchers DS Highlight cellular immunity; Fri, 19 Apr 2019 10:00:00 GMT BMP9 and pulmonary arterial hypertension https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2019/01_Sabine-Bailly.aspx Researchers DS Highlight BMP9;hypertension;BMP; Tue, 05 Mar 2019 11:00:00 GMT Nano-scales to weigh viruses https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L65_CMasselon.aspx Researchers IRIG Highlight Mass spectrometry; Mon, 31 Dec 2018 11:00:00 GMT BMP9, a promising tool for the expansion of lymphatic endothelial cell precursors https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L65_DVittet.aspx Researchers BAL Highlight BMP9;lymphangiogenesis; Mon, 31 Dec 2018 11:00:00 GMT Arrestins and calcium signaling https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L64_LAubry.aspx Researchers DS Highlight Dictyostelium;arrestin; Fri, 26 Oct 2018 10:00:00 GMT Clear-cell renal carcinoma: Towards a personalized medicine https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/FM_2018_BCI_OCochet.aspx Cancer Researchers ; Companies Biosanté Highlight renal cancer;kinase;kidney cancer; Thu, 13 Sep 2018 10:00:00 GMT Membrane remodeling: The role of Ubiquitin https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L63_MOFauvarque.aspx Researchers Grenoble Highlight ubiquitin;endocytosis;Cushing's disease;autophagy; Thu, 13 Sep 2018 10:00:00 GMT BMP9 and BMP10 pair in the bloodstream https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L63_ETillet.aspx Researchers Biosanté Highlight BMP10;BMP9;BMP;Rendu-Osler; Fri, 03 Aug 2018 10:00:00 GMT Meeting the challenge of proteomic analysis of histones https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L62_DPflieger.aspx Proteomics ; Epigenetics Researchers IRIG Highlight histone;epigenetics; Tue, 26 Jun 2018 10:00:00 GMT Accelerating the discovery of genes involved in oil production in microalgae https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L62_EMarechal.aspx Lipidomics ; 3rd generation biofuel Researchers ; Companies DS Highlight diatom;microalgae;biofuel;lipidomics; Tue, 26 Jun 2018 10:00:00 GMT A biomarker of response to antitumor treatment in metastatic renal cell carcinoma https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L62_IVilgrain.aspx Biomarkers ; Cancer Researchers Biosanté Highlight VE-cadherin;biomarker;renal cancer;kidney cancer; Tue, 26 Jun 2018 10:00:00 GMT Two microRNAs and their target genes involved in the aggressiveness of adrenocortical carcinoma https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L61_NCherradi.aspx Biomarkers Researchers DS Highlight miR-483-5p;adrenocortical tumorigenesis;miRNA;biomarker;miR-139-5p; Mon, 30 Apr 2018 10:00:00 GMT Direct transfection of clonal organoids https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L61_XGidrol.aspx Researchers IRIG Highlight 3D culture;organoids;microfluidics;Matrigel;organ-on-chip; Mon, 30 Apr 2018 10:00:00 GMT Bacterial pathogens can reprogram target cells by influencing epigenetic factors https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/FM_2018_Andrea-Dessen.aspx Infectious diseases Researchers DS Highlight virulence mechanisms;Pseudomonas;SST3;translocon; Sun, 01 Apr 2018 10:00:00 GMT The stress of infected cells is visible https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L60_EFaudry.aspx Infectious diseases Researchers DS Highlight Tue, 20 Feb 2018 11:00:00 GMT When the human spermatozoid helps to decipher the human proteome https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2018/L60_YVandenbrouck.aspx Proteomics Researchers DS Highlight proteomics; Tue, 20 Feb 2018 11:00:00 GMT Protein Kinase CK2 and cellular plasticity https://www.cea.fr/drf/irig/english/Pages/News/Highlights/2017/L59_OFilhol.aspx Cancer ; Stem cells Researchers IRIG Highlight EMT;stem cell;CK2; Tue, 05 Dec 2017 11:00:00 GMT