Direct Analysis of soil, water and biological fluids
What is Electrochemical micro-sensors
Electrochemical micro-sensor devices offer real-time information on complex environments by coupling a chemically selective layer to an electrochemical transducer. Electrochemical sensors provide a direct conversion of a biological event to an electronic signal. There are four main types of electrochemical sensors: potentiometric or ion-selective electrodes (ISEs), amperometric, impedimetric and transistors (OECT—organic electrochemical transistor, ISFET, etc.)
Electrochemical micro-sensors provide an attractive means to perform rapid and sensitive analysis.This technology also offers a high performance-cost ratio and is user friendly. Devices are now being used with success in clinical chemistry, food industry, and in environmental studies.
Applications:
Human and veterinarian healthcare for monitoring purposes: wearable devices for noninvasive physiological monitoring,
point-of-care testing and diagnostics,
wearable artificial organs,
post-surgery infection.
Environment and industrial studies for monitoring purposes: - water and soil quality,
- inline or in bioreactor process.
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What's new?
Electrochemical microfluidic-biosensors offers a wide range of improvements
for both health practitioners and scientists:
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Compact and low-cost devices
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Real-time and continuous multi-parametric measurement
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Biocompatible, flexible or pitch medium
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Autonomous devices: wireless communication, low energy consumption
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Formulation of sensitive and bio-sensitive layers for specific electrochemical detection
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Form factor, level of robustness depending on the application
The range of parameters measured covers: pH, Sodium (Na+), Potassium (K+), Calcium (Ca2+), Ammonium (NH4+), Carbon dioxide (CO2), Nitrate/nitrite (NO3-/ NO2-), Nitrogen monoxide (NO), Glucose (H2O2), Lactic acide, Creatinine.
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What's next?
CEA-Leti’s team is currently developing:
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Electrochemical sensors integrated into a microfluidic device—lab on a chip
Sensor networks for both cell culture and organ-on-chip
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Resorbable sensors
Sensors on paper
Liquid gated field effect transistors (LGFET) based on graphene
Coupling OECT and LGFET for design Boolean electrochemical sensors
Additional parameters are coming soon: Magnesium (Mg2+), Fluorine (F-), Phosphate (PO4-), Urea, heavy metal (Lead, Cadmium, Mercury, etc.), Arsenic