Bioscience and Biotechnology Institute of Aix-Marseille
LIPM, UMR 7265 (CEA/CNRS/AMU)
At the worldwide level, energy production is presently based for a large part on fossil resources and nuclear industry. Considering the increasing societal demand concerning environmental issues associated with energy production, it is necessary to investigate the consequences of these industries on living organisms. In line with the scientific policy of the CEA, and notably within the context of the CEA's "Toxicologie" transverse program, the Laboratory of Protein-Metal Interactions develops research in the field of environmental nuclear toxicology. Our main objectives are to better understand the consequences of bacteria exposure to radionuclides, determine molecular determinants of the speciation of the toxic species of interest in cells and at the protein level, and to develop innovative biotechnologies for biodetection and bioremediation strategies.
The objectives of the Laboratory are:
These projects are developed by a multidisciplinary approach of microbial ecology, genetics, genomics, biochemistry, biophysics (spectroscopy UV-Vis, fluorescence, infra-red spectroscopy, mass spectrometry, microcalorimetry).
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.