The Knowledge Factory - Sur le même thème https://www.cea.fr/drf/english/Pages/News/Scientific-results/2019/Rapid-genome-analysis-provides-invaluable-aid-for-hospitalized-newborns.aspx DRF english version en-US https://www.cea.fr/_layouts/15/images/i2i/icon-144x144-1033.png The Knowledge Factory - Sur le même thème https://www.cea.fr/drf/english 5,500 new RNA virus species identified in the global ocean https://www.cea.fr/drf/english/Pages/News/Scientific-results/2022/new-rna-virus-species-identified-in-the-global-ocean.aspx Using seawater samples collected during Tara Ocean expeditions and sequenced by the CEA-Jacob (Genoscope), an international team has identified 5,500 new species of RNA viruses, most of which belong to previously unknown phylogenetic branches. Metagenomics ; Oceanography ; Biodiversity general public ; Journalists ; Researchers Jacob Découvertes et avancées ; Scientific result Fri, 08 Apr 2022 10:00:00 GMT Using genomics to shed a light on climate https://www.cea.fr/drf/english/Pages/News/Scientific-results/2022/using-genomics-to-shed-a-light-on-climate.aspx Using metagenomic analysis, researchers from the CEA-Jacob/Genoscope and the LSCE (CEA-CNRS-UVSQ) have unveiled a “biogeography” of ocean plankton communities. Based on this work, they predict the evolution of their geographical distribution by 2100, with a reduction in the flux of organic carbon from surface waters to the depths. Climate ; Oceanography ; Carbon cycle ; Large-scale biology ; Metagenomics general public ; Journalists ; Researchers LSCE Découvertes et avancées ; Scientific result Tue, 05 Apr 2022 10:00:00 GMT Genetics and cerebral sulci: new findings based on the UK Biobank cohort https://www.cea.fr/drf/english/Pages/News/Scientific-results/2021/genetics-and-cerebral-sulci-new-findings-based-on-the-uk-biobank-cohort.aspx Using the UK Biobank cohort, researchers at the Joliot-NeuroSpin and the Jacob-CNRGH explored genome-wide associations between groups of linked genes (haplotypes) and the opening of brain sulci, an indicator of brain aging. Brain ; Medical imaging ; Genomics general public ; Journalists ; Researchers Joliot Découvertes et avancées ; Scientific result Tue, 01 Jun 2021 10:00:00 GMT COVID-19: using mass spectrometry to diagnose and assess viral load https://www.cea.fr/drf/english/Pages/News/Scientific-results/2021/covid-using-mass-spectrometry-to-diagnose-and-assess-viral-load.aspx A CEA-Joliot team is developing with the AP-HP a mass spectrometry diagnostic test for COVID-19 that would also make it possible to assess the patient’s viral load. Their aim is to make the method more sensitive and more compatible with hospital equipment. Diagnosis ; Proteomics general public ; Journalists ; Researchers Joliot Découvertes et avancées ; Scientific result Mon, 12 Apr 2021 10:00:00 GMT Testing for Antimicrobial Resistance using Artificial Intelligence https://www.cea.fr/drf/english/Pages/News/Scientific-results/2021/-Testing-for-Antimicrobial-Resistance-using-Artificial-Intelligence.aspx Health & life sciences ; Antibiotics ; Diagnosis News ; Press release ; Partnerships ; Scientific result Wed, 24 Feb 2021 11:00:00 GMT There is a specific signature of COVID-19 infections in the exhaled air of patients. https://www.cea.fr/drf/english/Pages/News/Scientific-results/2020/There-is-a-specific-signature-of-COVID-19-infections-in-the-exhaled-air-of-patients.aspx There is a specific signature of COVID infections in expired air in intubated and ventilated patients, referred to as "severe COVID patients". Explanations from CEA-Joliot and CEA-List. Diagnosis ; Virus Companies ; general public ; Institutions ; Journalists ; Researchers List News ; Scientific result Thu, 10 Dec 2020 11:00:00 GMT SARS-CoV-2 detection: mass spectrometry shows its potential for rapidity https://www.cea.fr/drf/english/Pages/News/Scientific-results/2020/SARS-CoV-2-detection-mass-spectrometry-shows-its-potential-for-rapidity.aspx A team from CEA-Joliot in Marcoule detected by mass spectrometry, in 3 minutes and without specific reagents, signature peptides of the SARS-CoV-2 virus in clinical samples (nasopharyngeal swabs). It thus provides a proof of concept of the use of this method as a possible alternative to PCR, currently the reference method. Infectious diseases ; Diagnosis Companies ; general public ; Institutions ; Journalists ; Researchers Joliot News ; Scientific result Fri, 07 Aug 2020 11:00:00 GMT Anisotropic functionalization of gold nanoparticles assisted by surface plasmons https://www.cea.fr/drf/english/Pages/News/Scientific-results/2020/Anisotropic-functionalization-of-gold-nanoparticles-assisted-by-surface-plasmons.aspx Researchers at the CEA-Iramis and their partners have locally grafted organic molecules onto gold nanoparticles, using two photopolymerization steps. This new flexible functionalization technique can be used for applications ranging from biosensing to photonics. Photonics ; Micro-nanotechnologies ; Chemistry ; Laser ; Diagnosis ; Innovation for industry general public ; Journalists ; Researchers Iramis Scientific result Wed, 05 Aug 2020 10:00:00 GMT Rapid genome analysis provides invaluable aid for hospitalized newborns https://www.cea.fr/drf/english/Pages/News/Scientific-results/2019/Rapid-genome-analysis-provides-invaluable-aid-for-hospitalized-newborns.aspx In their work entitled Fastgenomics, the Dijon Bourgogne University Hospital, Inserm and the CEA's National Center of Human Genomics Research (CNRGH) studied a rapid high-throughput genome sequencing process in 30 hospitalized newborns. The team was able to reduce the time needed for this process from an average of 18 months to only a month and a half at most (38 to 49 days), thus enabling rapid diagnoses for two-thirds of the patients. Genomics ; Diagnosis Companies ; general public ; Institutions ; Journalists ; Researchers Jacob News Wed, 18 Dec 2019 11:00:00 GMT Fast genome analysis helps with diagnosis for babies in neonatal intensive care https://www.cea.fr/drf/english/Pages/News/Scientific-results/2019/Fast-genome-analysis-helps-with-diagnosis-for-babies-in-neonatal-intensive-care.aspx Teams from CHU Dijon-Bourgogne, Inserm and the CEA have just produced genome analysis results for very sick newborn babies in neonatal intensive care, shortening the analysis time to 38 days compared to an average of 18 months at present. Diagnosis ; Genomics general public ; Journalists ; Researchers ; Companies Jacob Scientific result Wed, 11 Dec 2019 11:00:00 GMT The Tara Oceans mission reveals variations in plankton biodiversity and activity from the equator to the poles https://www.cea.fr/drf/english/Pages/News/Scientific-results/2019/The-Tara-Oceans-mission-reveals-variations-in-plankton-biodiversity-and-activity-from-the-equator-to-the-poles.aspx New results from the Tara Oceans expedition, led by a collaboration between the Tara Ocean Foundation and teams from the CNRS, EMBL, CEA, Sorbonne Université and Université Paris Science Lettres between 2009 and 2013 show that the diversity and functions of planktonic species in the global ocean change dramatically according to latitude. Biodiversity ; Genomics ; Environment ; Climate Companies ; general public ; Institutions ; Journalists ; Researchers Jacob Scientific result Mon, 18 Nov 2019 11:00:00 GMT Skin graft: a new molecular target for activating stem cells https://www.cea.fr/drf/english/Pages/News/Scientific-results/2019/Skin-graft-a-new-molecular-target-for-activating-stem-cells.aspx A CEA-Jacob team has just published a paper in which it demonstrates the central role of the transcription factor KLF4 in regulating the proliferation of epidermal stem cells and their ability to regenerate this tissue. This study opens perspectives for regenerative skin medicine. Fundamental Research ; Health & life sciences ; Cellular mechanisms ; Stem cells ; Genomics Companies ; general public ; Institutions ; Journalists ; Researchers Jacob Scientific result Wed, 23 Oct 2019 10:00:00 GMT Submarine symbiosis: microorganisms that never get lost https://www.cea.fr/drf/english/Pages/News/Scientific-results/2019/Submarine-symbiosis-microorganisms-that-never-get-lost--.aspx A team of CEA-Biam has uncovered a symbiotic behavior between magnetism-using bacteria and eukaryotic microorganisms. Biodiversity ; Bacteria ; Genomics Researchers ; Journalists ; general public BIAM En direct ; Scientific result Tue, 14 May 2019 10:00:00 GMT Tara Oceans: discovery of over 100 million genes from the marine world. https://www.cea.fr/drf/english/Pages/News/Scientific-results/2018/Tara-Oceans--découverte-de-plus-de-100-millions-de-gènes-issus-du-monde-marin.aspx Continuing the analysis and exploitation of the biggest database compiled on the planktonic ecosystem, the teams from the CEA, CNRS (French National Centre for Scientific Research), EMBL (European Molecular Biology Laboratory) and the French graduate school ENS, among others[1], have just reached a new milestone by analysing the expression of over 100 million genes Health & life sciences ; Genomics Journalists ; Researchers ; general public GENOSCOPE News ; Press release ; Focus Thu, 25 Jan 2018 11:00:00 GMT Nanopore sequencing conquers a tomato https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/nanopore-sequencing-conquers-a-tomato.aspx A team from the Institut François-Jacob participated in establishing the complete genome of a tomato using the MinION, demonstrating the new potential of nanopore technology. Genomics Researchers ; general public ; Journalists Fontenay-aux-Roses Scientific result Wed, 06 Dec 2017 11:00:00 GMT Multiplying the Sensitivity of Biological Analyses by Thirty Thanks to Microfluidics https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/multiplying-the-sensitivity-of-biological-analyses.aspx In collaboration with scientists from the Frédéric-Joliot Institute, a team from IRAMIS has developed a microfluidic device coupled with a mass spectrometry technique. The scientists were able to multiply the analysis sensitivity by thirty compared to the current state of the art, as shown by a spectrum obtained using this process on a deposit of a model peptide of a few femtomoles (10-15). Diagnosis Researchers ; general public ; Journalists Iramis Scientific result Tue, 07 Nov 2017 11:00:00 GMT Schizophrenia and Bipolar Disorder Share a Common Molecular Mechanism https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/schizophrenia-and-bipolar-disorder-share-a-common-molecular-mechanism.aspx A team of scientists from the Frédéric-Joliot Institute and their partners have shown that a genetic variant associated with multiple psychiatric disorders alters a prefrontal-limbic network, that is suspected to increase the risk of schizophrenia or bipolar disorder. Genomics ; Diseases Researchers ; Journalists ; general public Joliot Scientific result Fri, 13 Oct 2017 10:00:00 GMT New Step Towards a Better Evaluation of Human Gut Microbiota https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/new-step-towards-a-better-evaluation-of-human-gut-microbiota.aspx The standardization of metagenomic methods is a prerequisite to better understand the human gut microbiota. The step of DNA extraction in this method is critical. Metagenomics ; Bacteria Researchers ; general public ; Journalists GENOSCOPE Scientific result Mon, 09 Oct 2017 10:00:00 GMT Deciphering the Fall Armyworm as it Invades Africa https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/deciphering-the-fall-armyworm-as-it-invades-africa.aspx In collaboration with the CEA François-Jacob Institute and INRIA, scientists from INRA have sequenced the genome of butterfly Spodoptera frugiperda. This common agricultural pest in the Americas is now moving towards the East. Genomics ; Biodiversity Journalists ; Researchers ; general public Fontenay-aux-Roses Scientific result Wed, 27 Sep 2017 10:00:00 GMT Magnetic Nanotweezers to Grab Bacteria or Cells https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/magnetic-nanotweezers-to-grab-bacteria-or-cells.aspx A team from INAC has developed “nanotweezers” operating through remote actuation by an external magnetic field. Inspired from microelectronics techniques, they may collect microscopic biological samples for analysis—biopsies in particular. Diagnosis Researchers ; general public ; Journalists Inac Scientific result nanotechnologie;biopsie;ADN;diagnostic;Microélectronique;silicium; Tue, 13 Jun 2017 10:00:00 GMT Using Diffusion MRI to Estimate Tissue Stiffness https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/unsing-diffusion-mri-to-estimate-tissue-stiffness.aspx A collaboration between Japanese researchers and a team from the Frédéric-Joliot Institute at CEA has shown that liver lesions can be characterized from their elastic properties as estimated virtually using diffusion MRI. MRI ; Diagnosis Researchers ; general public ; Journalists Joliot Scientific result Tue, 13 Jun 2017 10:00:00 GMT The Success of Nematodes in the Absence of Sex Partly Explained https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/the-success-of-nematodes-in-the-absence-of-sex-partly-explained.aspx Root-knot nematodes are devastating species to global agriculture; those that reproduce asexually are especially thriving. Researchers from CEA-Genoscope and their partners proposed a hypothesis to explain this extraordinary success. Genomics ; Biodiversity Researchers ; general public ; Journalists Jacob Scientific result Mon, 12 Jun 2017 10:00:00 GMT Tracking Down an Aneurysm https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/tracking-down-an-aneurysm.aspx A team from the CEA Frédéric-Joliot Institute has developed new optical probes for non-invasive imaging. These chemical tools could lead to the development of diagnostic agents to better characterize the risk of aortic aneurysm. Diagnosis ; Medical imaging Journalists ; general public ; Researchers Joliot Scientific result Fri, 05 May 2017 10:00:00 GMT A new giant virus discovered in the Siberian permafrost https://www.cea.fr/drf/english/Pages/News/Scientific-results/2015/new-giant-virus-discovered-Siberian-permafrost.aspx A giant virus from a completely new genus was discovered in a Siberian permafrost sample dating back 30,000 years. Genomics, transcriptomics, proteomics and metagenomics draw a detailed portrait of this new virus, known as Mollivirus sibericum. Biodiversity ; Genomics Fontenay-aux-Roses Scientific result Mon, 07 Sep 2015 10:00:00 GMT First mitochondrial genome of an extinct bison species https://www.cea.fr/drf/english/Pages/News/Scientific-results/2015/First-mitochondrial-genome-extinct-bison-species.aspx ​A team from the CEA-IBITECS located at the Musée de l'Homme has just determined the complete mitochondrial genome of a steppe bison specimen from a bone fragment dating back 19,000 years, found in the Trois-Frères cave (Ariège). Genomics ; Biodiversity Saclay Scientific result Wed, 17 Jun 2015 10:00:00 GMT Tara Oceans: 40 million new genes decoded https://www.cea.fr/drf/english/Pages/News/Scientific-results/2015/Tara-Oceans-40-million-new-genes-decoded.aspx A special issue of the journal Science features the first results from the Tara Oceans expedition with five publications, in which the CEA-IG participated. Genomics ; Biodiversity GENOSCOPE Scientific result Mon, 25 May 2015 10:00:00 GMT The oak genome has been sequenced https://www.cea.fr/drf/english/Pages/News/Scientific-results/2015/oak-genome-sequenced.aspx Research teams from INRA and the CEA have just sequenced for the first time the genome of the pedunculate oak tree, which is widely distributed throughout the northern hemisphere. This work will improve our understanding of the adaptive mechanisms of trees to environmental variations, and will thus provide elements that can be used to anticipate their responses to climate change. Genomics ; Impact of climate change Fontenay-aux-Roses Scientific result Mon, 11 May 2015 10:00:00 GMT Bio-magnet for targeted medical imaging https://www.cea.fr/drf/english/Pages/News/Scientific-results/2015/Bio-magnet-for-targeted-medical-imaging.aspx The CEA-IBEB has partnered with the CEA-I2BM to develop original MRI contrast agents. Nano-magnets produced by bacteria may reveal targets at the molecular level. Biotechnology ; Cell and molecular imaging ; MRI ; Diagnosis ; Nanomedicine LBC Scientific result Fri, 20 Feb 2015 11:00:00 GMT The coffee plant: a well-preserved genome https://www.cea.fr/drf/english/Pages/News/Scientific-results/2014/The-coffee-plant-a-well-preserved-genome.aspx An international consortium coordinated by the CEA-IG (Genoscope) has just published the reference sequence of the coffee plant genome. This plant is of paramount economic importance. Large-scale biology ; Genomics Fontenay-aux-Roses Scientific result ; European & international partnerships Fri, 05 Sep 2014 10:00:00 GMT Canola: the genomic portrait of a “recent” species https://www.cea.fr/drf/english/Pages/News/Scientific-results/2014/Canola-the-genomic-portrait-of-a-recent-species.aspx An international consortium led by INRA and the CEA (IG-Genoscope) has just published the reference sequence of the canola genome. This is a choice tool for varietal improvement. Large-scale biology ; Genomics GENOSCOPE Scientific result Fri, 22 Aug 2014 10:00:00 GMT A big step towards the sequencing of wheat https://www.cea.fr/drf/english/Pages/News/Scientific-results/2014/A-big-step-towards-the-sequencing-of-wheat.aspx An international collaboration led by INRA and the CEA-IG (Genoscope) has published the first reference sequence of a chromosome from wheat. This is a decisive step towards sequencing its entire genome. Genomics GENOSCOPE Scientific result ; European & international partnerships Thu, 17 Jul 2014 10:00:00 GMT Intestinal microflora: a wealth of new species https://www.cea.fr/drf/english/Pages/News/Scientific-results/2014/Intestinal-microflora-a-wealth-of-new-species.aspx An international consortium involving teams from the CEA-IG has developed a new method for analyzing metagenomes. This method has been successfully applied to intestinal microflora, revealing hundreds of previously unknown species. Metagenomics ; Biodiversity IG Scientific result ; European & international partnerships Mon, 07 Jul 2014 10:00:00 GMT Rainbow trout: a surprising genome https://www.cea.fr/drf/english/Pages/News/Scientific-results/2014/Rainbow-trout-a-surprising-genome.aspx A French consortium, coordinated by INRA and involving the CEA (Genoscope), the CNRS and the Ecoles Normales Supérieures of Paris and Lyon, has sequenced and analyzed the genome of the rainbow trout . The result challenges a classic hypothesis in genetics. Biodiversity ; Agronomy ; Genomics Fontenay-aux-Roses Scientific result Tue, 22 Apr 2014 10:00:00 GMT Discovery of a new type of giant virus more than 30,000 years old https://www.cea.fr/drf/english/Pages/News/Scientific-results/2014/Discovery-of-a-new-type-of-giant-virus-more-than-30000-years-old.aspx A new type of giant virus, dubbed “Pithovirus”, was discovered in the frozen soil of extreme northeast Siberia by researchers from the CNRS/Aix-Marseille Université, CEA-IRTVS, CEA-IG and the Russian Academy of Sciences. Buried in the ground, this giant virus has survived more than 30,000 years of freezing. Genomics ; Biodiversity ; Evolution GENOSCOPE Scientific result Tue, 04 Mar 2014 11:00:00 GMT Is the disappearance of mammoths related to changes in Arctic flora? https://www.cea.fr/drf/english/Pages/News/Scientific-results/2014/Is-the-disappearance-of-mammoths-related-to-changes-in-Arctic-flora.aspx ​The mass extinction of large animals during the last ice age is due to the climate, but what are the specific reasons for this? A collaboration involving 30 teams from 12 countries, including the CEA-IG, has provided some answers by sequencing free DNA taken from the Arctic permafrost. Evolution ; Metagenomics IG Scientific result Fri, 07 Feb 2014 11:00:00 GMT The flower protein reveals a part of its history https://www.cea.fr/drf/english/Pages/News/Scientific-results/2014/The-flower-protein-reveals-a-part-of-its-history.aspx The protein LEAFY plays an essential role in the beauty of the plant world, as it governs the formation of flowers. As part of an international collaboration, a joint team including the CEA-IRTSV has managed to trace its history and to elucidate the evolutionary mechanism that gave it the ability to direct floral morphogenesis. Evolution ; Genomics Grenoble Scientific result Fri, 17 Jan 2014 11:00:00 GMT 400 exomes sequenced https://www.cea.fr/drf/english/Pages/News/Scientific-results/2013/400-exomes-sequenced.aspx 400 exomes were sequenced by the CEA-IG-CNG through a partnership with the Fondation maladies rares. Genomics ; Autoimmune diseases ; Neurodegenerative diseases ; Infectious diseases Fontenay-aux-Roses Scientific result Fri, 13 Dec 2013 11:00:00 GMT Looking for the function of proteins https://www.cea.fr/drf/english/Pages/News/Scientific-results/2013/Looking-for-the-function-of-proteins.aspx CEA Researchers from the CEA-IG propose a novel method to clarify enigmatic functions of proteins. This study was published online November 17th in the journal Nature Chemical Biology. Genomics Fontenay-aux-Roses Scientific result Fri, 15 Nov 2013 11:00:00 GMT Genomics: an animal reproducing asexually tells its secrets https://www.cea.fr/drf/english/Pages/News/Scientific-results/2013/Genomics-an-animal-reproducing-asexually-tells-its-secrets.aspx The genome of a bdelloid rotifer – a microscopic animal whose surprising capacity for survival and reproduction is the subject of much debate – has been sequenced and analyzed by an international consortium jointly directed by the CEA-Genoscope and the University of Namur. Genomics ; Evolution Fontenay-aux-Roses Scientific result Mon, 22 Jul 2013 10:00:00 GMT Retracing the evolutionary history and emergence of tuberculosis https://www.cea.fr/drf/english/Pages/News/Scientific-results/2013/Retracing-the-evolutionary-history-and-emergence-of-tuberculosis.aspx Scientists from the Pasteur Institutes in Paris and Lille, the CNRS, INRSERM and the Université Lille 2, in collaboration with the CEA-Genoscope and the Sanger Institute, have recently determined the origin of the emergence of the bacteria Mycobacterium tuberculosis, the primary causative agent of tuberculosis. Genomics ; Evolution Fontenay-aux-Roses Scientific result Mon, 07 Jan 2013 11:00:00 GMT