The Knowledge Factory - Sur le même thème https://www.cea.fr/drf/english/Pages/News/Scientific-results/2021/covid-using-mass-spectrometry-to-diagnose-and-assess-viral-load.aspx DRF english version en-US https://www.cea.fr/_layouts/15/images/i2i/icon-144x144-1033.png The Knowledge Factory - Sur le même thème https://www.cea.fr/drf/english Parkinson’s disease: reduced immune support is involved https://www.cea.fr/drf/english/Pages/News/Scientific-results/2021/parkinsons-disease-reduced-immune-support-is-involved.aspx As part of a European collaboration, researchers at the CEA-Jacob have demonstrated that exposure to aggregates of α-synuclein proteins could reduce the support capacity of the brain’s immune cells, the astrocytes. Parkinson's disease ; Structural biology ; Proteomics general public ; Journalists ; Researchers Jacob Découvertes et avancées ; Scientific result Mon, 03 May 2021 10:00:00 GMT How plants handle stress through their stomata https://www.cea.fr/drf/english/Pages/News/Scientific-results/2021/how-plants-handle-stress-through-their-stomata.aspx Researchers at the Biam have unveiled one of the mechanisms involved in the responses of plants to variations in their environment. This work could help improve their capacity to adapt to climate change. Proteomics ; Structural biology ; Cellular mechanisms general public ; Journalists ; Researchers BIAM Découvertes et avancées ; Scientific result Mon, 26 Apr 2021 10:00:00 GMT COVID-19: using mass spectrometry to diagnose and assess viral load https://www.cea.fr/drf/english/Pages/News/Scientific-results/2021/covid-using-mass-spectrometry-to-diagnose-and-assess-viral-load.aspx A CEA-Joliot team is developing with the AP-HP a mass spectrometry diagnostic test for COVID-19 that would also make it possible to assess the patient’s viral load. Their aim is to make the method more sensitive and more compatible with hospital equipment. Diagnosis ; Proteomics general public ; Journalists ; Researchers Joliot Découvertes et avancées ; Scientific result Mon, 12 Apr 2021 10:00:00 GMT Protein crown around nanoparticles: Size matters! https://www.cea.fr/drf/english/Pages/News/Scientific-results/2021/protein-crown-around-nanoparticles---size-matters.aspx When immersed in biological media, nanoparticles are immediately "wrapped" in proteins. A study conducted by researchers from the Iramis and Joliot (I2BC) institutes clarifies the importance of protein size on the formation of this envelope and recommends better consideration of this parameter in proteomic and nanotoxicological studies. Micro-nanotechnologies ; Nanomedicine ; Proteomics ; Nanotoxicology general public ; Journalists ; Researchers Iramis Scientific result Wed, 03 Mar 2021 11:00:00 GMT Testing for Antimicrobial Resistance using Artificial Intelligence https://www.cea.fr/drf/english/Pages/News/Scientific-results/2021/-Testing-for-Antimicrobial-Resistance-using-Artificial-Intelligence.aspx Health & life sciences ; Antibiotics ; Diagnosis News ; Press release ; Partnerships ; Scientific result Wed, 24 Feb 2021 11:00:00 GMT There is a specific signature of COVID-19 infections in the exhaled air of patients. https://www.cea.fr/drf/english/Pages/News/Scientific-results/2020/There-is-a-specific-signature-of-COVID-19-infections-in-the-exhaled-air-of-patients.aspx There is a specific signature of COVID infections in expired air in intubated and ventilated patients, referred to as "severe COVID patients". Explanations from CEA-Joliot and CEA-List. Diagnosis ; Virus Companies ; general public ; Institutions ; Journalists ; Researchers List News ; Scientific result Thu, 10 Dec 2020 11:00:00 GMT SARS-CoV-2 detection: mass spectrometry shows its potential for rapidity https://www.cea.fr/drf/english/Pages/News/Scientific-results/2020/SARS-CoV-2-detection-mass-spectrometry-shows-its-potential-for-rapidity.aspx A team from CEA-Joliot in Marcoule detected by mass spectrometry, in 3 minutes and without specific reagents, signature peptides of the SARS-CoV-2 virus in clinical samples (nasopharyngeal swabs). It thus provides a proof of concept of the use of this method as a possible alternative to PCR, currently the reference method. Infectious diseases ; Diagnosis Companies ; general public ; Institutions ; Journalists ; Researchers Joliot News ; Scientific result Fri, 07 Aug 2020 11:00:00 GMT Anisotropic functionalization of gold nanoparticles assisted by surface plasmons https://www.cea.fr/drf/english/Pages/News/Scientific-results/2020/Anisotropic-functionalization-of-gold-nanoparticles-assisted-by-surface-plasmons.aspx Researchers at the CEA-Iramis and their partners have locally grafted organic molecules onto gold nanoparticles, using two photopolymerization steps. This new flexible functionalization technique can be used for applications ranging from biosensing to photonics. Photonics ; Micro-nanotechnologies ; Chemistry ; Laser ; Diagnosis ; Innovation for industry general public ; Journalists ; Researchers Iramis Scientific result Wed, 05 Aug 2020 10:00:00 GMT Rapid genome analysis provides invaluable aid for hospitalized newborns https://www.cea.fr/drf/english/Pages/News/Scientific-results/2019/Rapid-genome-analysis-provides-invaluable-aid-for-hospitalized-newborns.aspx In their work entitled Fastgenomics, the Dijon Bourgogne University Hospital, Inserm and the CEA's National Center of Human Genomics Research (CNRGH) studied a rapid high-throughput genome sequencing process in 30 hospitalized newborns. The team was able to reduce the time needed for this process from an average of 18 months to only a month and a half at most (38 to 49 days), thus enabling rapid diagnoses for two-thirds of the patients. Genomics ; Diagnosis Companies ; general public ; Institutions ; Journalists ; Researchers Jacob News Wed, 18 Dec 2019 11:00:00 GMT Fast genome analysis helps with diagnosis for babies in neonatal intensive care https://www.cea.fr/drf/english/Pages/News/Scientific-results/2019/Fast-genome-analysis-helps-with-diagnosis-for-babies-in-neonatal-intensive-care.aspx Teams from CHU Dijon-Bourgogne, Inserm and the CEA have just produced genome analysis results for very sick newborn babies in neonatal intensive care, shortening the analysis time to 38 days compared to an average of 18 months at present. Diagnosis ; Genomics general public ; Journalists ; Researchers ; Companies Jacob Scientific result Wed, 11 Dec 2019 11:00:00 GMT Multiplying the Sensitivity of Biological Analyses by Thirty Thanks to Microfluidics https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/multiplying-the-sensitivity-of-biological-analyses.aspx In collaboration with scientists from the Frédéric-Joliot Institute, a team from IRAMIS has developed a microfluidic device coupled with a mass spectrometry technique. The scientists were able to multiply the analysis sensitivity by thirty compared to the current state of the art, as shown by a spectrum obtained using this process on a deposit of a model peptide of a few femtomoles (10-15). Diagnosis Researchers ; general public ; Journalists Iramis Scientific result Tue, 07 Nov 2017 11:00:00 GMT Magnetic Nanotweezers to Grab Bacteria or Cells https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/magnetic-nanotweezers-to-grab-bacteria-or-cells.aspx A team from INAC has developed “nanotweezers” operating through remote actuation by an external magnetic field. Inspired from microelectronics techniques, they may collect microscopic biological samples for analysis—biopsies in particular. Diagnosis Researchers ; general public ; Journalists Inac Scientific result nanotechnologie;biopsie;ADN;diagnostic;Microélectronique;silicium; Tue, 13 Jun 2017 10:00:00 GMT Using Diffusion MRI to Estimate Tissue Stiffness https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/unsing-diffusion-mri-to-estimate-tissue-stiffness.aspx A collaboration between Japanese researchers and a team from the Frédéric-Joliot Institute at CEA has shown that liver lesions can be characterized from their elastic properties as estimated virtually using diffusion MRI. MRI ; Diagnosis Researchers ; general public ; Journalists Joliot Scientific result Tue, 13 Jun 2017 10:00:00 GMT Tracking Down an Aneurysm https://www.cea.fr/drf/english/Pages/News/Scientific-results/2017/tracking-down-an-aneurysm.aspx A team from the CEA Frédéric-Joliot Institute has developed new optical probes for non-invasive imaging. These chemical tools could lead to the development of diagnostic agents to better characterize the risk of aortic aneurysm. Diagnosis ; Medical imaging Journalists ; general public ; Researchers Joliot Scientific result Fri, 05 May 2017 10:00:00 GMT Bio-magnet for targeted medical imaging https://www.cea.fr/drf/english/Pages/News/Scientific-results/2015/Bio-magnet-for-targeted-medical-imaging.aspx The CEA-IBEB has partnered with the CEA-I2BM to develop original MRI contrast agents. Nano-magnets produced by bacteria may reveal targets at the molecular level. Biotechnology ; Cell and molecular imaging ; MRI ; Diagnosis ; Nanomedicine LBC Scientific result Fri, 20 Feb 2015 11:00:00 GMT Pandoravirus: missing link discovered between viruses and cells https://www.cea.fr/drf/english/Pages/News/Scientific-results/2013/Pandoravirus-missing-link-discovered-between-viruses-and-cells.aspx Researchers at IGS, the genomic and structural information laboratory, working in association with the large-scale biology laboratory have just discovered two giant viruses which, in terms of number of genes, are comparable to certain eukaryotes, microorganisms with nucleated cells. Evolution ; Proteomics BIG Scientific result Fri, 19 Jul 2013 10:00:00 GMT