François Jacob Institute of biology - On the same theme https://jacob.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2022/Genoscope-D4GEN-Hackathon.aspx Website of the François Jacob Institute of Biology en-US https://jacob.cea.fr/drf/ifrancoisjacob/SiteAssets/logo-cea-JACOB.png François Jacob Institute of biology - On the same theme https://jacob.cea.fr/drf/ifrancoisjacob/english Mirusvirus : at the crossroads of evolution https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2023/mirusvirus-crossroads-evolution.aspx Using samples collected during the Tara Oceans expeditions and sequencing "big data" generated by Genoscope, an international research team has discovered an important group of DNA viruses living among ocean surface plankton. Published in Nature, this discovery brings novel opportunities for the field of ecology and the elucidation of DNA virus evolution pathways, in the seas and beyond. Genomics ; Metagenomics ; Bioinformatic ; Oceanography ; Biodiversity ; Environment Researchers ; general public ; Journalists GENOSCOPE Highlight ; Scientific result Tara Oceans;viruses;metagenome;DNA;ocean;Evolution;biodiversity;plankton; Thu, 20 Apr 2023 10:00:00 GMT Marine microbiome : Genoscope contributes to the European project BlueRemediomics https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2023/microbiome-marin-genoscope-blueremediomics.aspx Launched in December 2022, the European project BlueRemediomics aims to valorize currently unexploited marine microbial resources. The four-year project brings together an international consortium of experts, including the Genomics Metabolics mixed research unit (Genoscope/CEA-Jacob), and enables the development of novel tools and approaches to explore marine microbiome data. Biodiversity ; Oceanography ; Genomics ; Environment Researchers ; Journalists DRF Live in the center ; Highlight biodiversity;marine microorganisms;marine microbiome;blueremediomics;genome;metagenome;ecosystem; Fri, 17 Feb 2023 11:00:00 GMT Primary hyperaldosteronism and arterial hypertension : the genome under a microscope https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2022/primary-hyperaldosteronism-hypertension-genome.aspx For a study they published in Nature Communications, researchers from the CNRGH and PARCC joined forces to unprecedentedly identify genome loci associated with a risk of primary hyperaldosteronism (PHA), the most frequent cause of secondary arterial hypertension. Genomics Researchers ; Journalists ; general public DRF Scientific result ; Highlight genome loci;hypertension;aldosterone;primary hyperaldosteronism; Wed, 30 Nov 2022 11:00:00 GMT ATLASea selected for Priority Programs and Equipment for Research action https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2022/ATLASea-Priority -Programs -equipment-reesearch.aspx The ATLASea program, forwarded by Genoscope (CEA-Jacob/CNRS), has been chosen as a laureate of the Priority Programs and Equipment for Research action. The program's objective is to sequence and analyze the genomes of 5,000 marine species. Genomics ; Environment ; Biodiversity ; Large-scale biology Researchers ; Journalists ; general public DRF Live in the center ; Highlight genomics;marine species;ATLASea;PEPR;sequencing; Wed, 27 Jul 2022 10:00:00 GMT The French Academy of Sciences recognizes work in climate genomics https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2022/french-academy-sciences-work-climate-genomics.aspx In June 2022, six young researchers were recognized for their major scientific contributions to biology at the French Academy of Sciences' "Great French Advances in Biology" event. Among them was Paul Frémont, PhD student at Genoscope (CEA-Jacob) and LSCE. Genomics ; Climate Researchers ; Journalists ; general public LSCE Prizes and awards ; Live in the center climate;genomics; Mon, 04 Jul 2022 10:00:00 GMT Genoscope takes part in the first D4GEN Hackathon https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2022/Genoscope-D4GEN-Hackathon.aspx Genopole held its first D4GEN Hackathon on 19–21 May 2022 with the goal of creating interdisciplinary, computational genomics communities aimed particularly at the sharing, preservation and (re)use of genomics Big Data. Jérôme Arnoux, PhD student at LABGeM (Genoscope), led the team that took home the third-place prize from that competition. Genomics Researchers ; Journalists ; general public DRF Live in the center ; Highlight hackathon;genomics; Wed, 08 Jun 2022 10:00:00 GMT CEA-Jacob involved in a new program dedicated to beetle genetics https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2022/CEA-Jacob-involved-program-beetle-genetics.aspx CEA-Jacob is collaborating with Ÿnsect in an industrial program, ŸNFABRE, devoted to the genetics of the Tenebrio Molitor beetle larva. This program has been awarded funding under the "Structuring Projects for Competitiveness" program of the French government's investment program for the future (PIA), operated by Bpifrance. It is in line with the actions carried out by Ÿnsect and the CEA, recently supported by Horizon H2020 and the ANR. Genomics Researchers ; Journalists ; general public DRF Highlight ; Live in the center tenebrio molitor;genetic selection;beetle;mealworm;sequencing; Thu, 19 May 2022 10:00:00 GMT 5,500 new RNA virus species identified in the world's oceans https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2022/RNA-virus-species-world-oceans.aspx Working from 35,000 worldwide water and plankton samples collected by the Tara Oceans Expeditions and sequenced by Genoscope,, an international team of researchers has identified 5,500 new RNA virus species and met the challenge of their phylogenetic classification. The team's work was published in Science. Genomics ; Metagenomics ; Bioinformatic ; Transcriptomics ; Oceanography ; Environment Researchers ; Journalists ; general public GENOSCOPE Scientific result ; Highlight Tara Oceans;plankton;RNA;ocean;biodiversity;viruses;ecosystem; Fri, 08 Apr 2022 10:00:00 GMT MULTILAYER: a new tool to digitize biological tissues https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2021/Multilayer-tool-digitize-biological-tissues.aspx In a study published in Cell Systems, the SysFate laboratory (UMR8030/Genoscope/CEA-Jacob) presented MULTILAYER, an algorithm that provides digital functional maps of biological organs or tissues. Genomics ; Cell and molecular imaging Researchers ; Journalists ; general public DRF Highlight ; Scientific result digitize;multilayer;spatial transcriptomics; Tue, 15 Jun 2021 10:00:00 GMT COVID-19 durably affects the intestinal microbiota https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2021/COVID-19-affects-intestinal-microbiota.aspx The microbial composition and metabolome of the intestinal microbiota of an animal model for COVID-19 were altered over the disease course and remained so after the resolution of lung infection. Those results, which will contribute were brought to light by the Institut Pasteur in Lille in partnership with IDMIT (CEA-Jacob). Infectious diseases ; Metagenomics Researchers ; Journalists ; general public DRF News ; Scientific result dysbiosis;intestinal microbiota;COVID 19;SARS-CoV2; Wed, 05 May 2021 10:00:00 GMT A virus at home in parasitic wasps https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2021/virus-at-home-in-parasitic-wasps.aspx Genoscope was part of an international team that assembled the genome of Cotesia wasps and identified therein chromosomal colonization by a virus that settled into the wasp genome a hundred-million years ago. Their results suggest that the evolutionary course of a virus integrated within the genome of a eukaryote changes completely when the former is beneficial to the latter. Genomics ; Bioremediation ; Virus Scientific result virus;genomics;wasps;cotesia; Sun, 14 Feb 2021 11:00:00 GMT Big pangenomics to study microbial genomic diversity https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2021/big-pangenomics-study-microbial-genomic-diversity.aspx Researchers from LABGeM (CEA-Jacob), LaMME and the Pasteur Institute joined forces to develop a novel method for the analysis of prokaryote pangenomes, called PPanGGoLiN. As a complement to PPanGGoLiN, the team developed a second tool, panRGB, which brought unprecedented performance and speed to massive comparative genomics analyses. Genomics Researchers ; Journalists ; general public DRF Scientific result panRGP;PPanGGoLiN;pangenome;microbial genome;metagenome;procaryote;bioinformatics; Sun, 07 Feb 2021 11:00:00 GMT POSCOVD : a new project from Genoscope for the diagnosis of COVID-19 https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2021/POSCOVD-project-diagnosis-Covid-19-Genoscope.aspx ​At the most-recent DIM ELICIT colloquium, Marco Mendoza, team leader at SysFate (UMR8030/Genoscope/CEA-Jacob), presented his project POSCOVD, financed by the special Fight-SARS-Cov2 call for projects. POSCOVD seeks to develop a large-scale COVID-19 screening methodology, building particularly upon high throughput sequencing technologies (Oxford Nanopore Sequencing). Genomics ; Diagnosis ; Virus Researchers ; general public ; Journalists DRF Live in the center sequencing;nanopore;DIM ELICIT;Covid19;COVID 19;SARS-CoV-2;diagnosis; Sat, 06 Feb 2021 11:00:00 GMT Discovering the ocean's microbiome: A new Tara expedition https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2021/Discovering-ocean-microbiome-new-Tara-expedition.aspx On 12 December 2020, the schooner Tara set sail from Lorient, France, for a new two-year scientific expedition. The voyage will cover 70,000 kilometers in the South Atlantic, along the African and South-American coasts and on to Antarctica. The expedition's objective is to explore the oceanic microbiome and determine its future in the current era of climate change.Conceived by the Tara Ocean Foundation, the CNRS, the CEA and the EMBL¹, the mission will involve close to 200 scientists across 42 research structures—including Genoscope (CEA-Jacob). Biodiversity ; Impact of climate change ; Oceanography ; Large-scale biology ; Metagenomics ; Metabolomics general public ; Journalists ; Researchers GENOSCOPE News Plastic;climate change;plankton;metagenome;microbiome;microorganism;schooner;Tara;ocean; Sun, 13 Dec 2020 11:00:00 GMT Tara Oceans: more news on plankton https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2020/tara-oceans-more-news-on-plankton.aspx A team from the Genomics Metabolics laboratory (Genoscope / CEA-Jacob) has developed a bioinformatics analysis method for environmental genomics data and applied it to those of plankton resulting from the Tara Oceans expeditions. The method reconstructs transcriptomes of eukaryotes from environmental sequencing data, thus enabling access to the genetic organization of these organisms, even those that have not yet been described, to study their functional potential. Also, with the method, interspecies associations can be identified across samples taken in different oceanic provinces. The novel approach is a door to the environmental context and biological functions of numerous species of ecological interest. The team's work was published in Genome Research. Biodiversity ; Metagenomics ; Transcriptomics ; Genomics Researchers ; general public ; Journalists DRF Highlight ; Scientific result Tara Oceans;Climat;cyanobacteria;Environment;ocean;plankton;genomics; Fri, 26 Jun 2020 10:00:00 GMT MicroScope: an integrated platform for the functional exploration and annotation of microbial genes https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2020/MicroScope-integrated-platform-functional-exploration-annotation-microbial-genes.aspx The platform MicroScope was launched in 2002 by LABGeM (Genoscope) to provide the international microbiology community with bioinformatics tools for the analysis and exploration of prokaryote genomes. The platform's innovations were recently highlighted in a special edition of Nucleic Acids Research on databases. The journal's readers can discover MicroScope's recent developments for the functional annotation of genes, the characterization of genomic islands, and the analysis of pan-genomes. Genomics ; Bioinformatic Researchers ; Journalists ; general public DRF Scientific result microbe;Microbiology;pan-genome;prokaryote;bio-informatic;genomic; Tue, 19 May 2020 10:00:00 GMT Oak genomics proves its worth https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2020/Oak-genomics-proves-its-worth.aspx A year and a half after the publication of the complete sequence of the pedunculated oak genome by a national consortium led by INRAE and CEA (Genoscope), the first results based on this genomic resource are the subject of a series of articles published on 16 April 2020 in the journal New Phytologist. Genomics Researchers ; Journalists DRF Highlight ; Scientific result Gene Sequence;Oak Tree;genome;Oak;genomic; Fri, 17 Apr 2020 10:00:00 GMT Meet My Platform / Paris Saclay University - Life Sciences #2 https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2020/Meet-My-Platform-Paris-Saclay-University-Life-Sciences-2.aspx On November 17, 2020, the Life Sciences invite you to their second edition of Meet My Platform | Paris-Saclay University, co-organized with Genopole. Come and discover the potential of technology platforms at Paris-Saclay University. 113 academic platforms and 20 industrial sponsors meet in a dedicated area. Among the speakers of the day, Jean-François Deleuze will present the Centre de Référence d'Innovation et d'Expertise (CRefIX) that he manages, and how this structure allows the development of sequencing protocols for the medicine of the future. Genomics Researchers ; Journalists DRF Agenda ; Highlight diagnostic;sequencing;genomic;genetic; Thu, 26 Mar 2020 11:00:00 GMT International Symposium on Human Genetics and Medical Genomics https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2019/International-Symposium-on-Human-Genetics-and-Medical-Genomics.aspx France Génomique is proud to announce its first Human Genomics international symposium that will be held in Paris from February 10th to 12th, 2020. Registrations are open. Genomics Researchers CNRGH Conference Gene Sequence;genome; Wed, 04 Dec 2019 15:26:02 GMT Skin graft: a new molecular target for activating stem cells https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Press/2019/Skin-graft-a-new-molecular-target-for-activating-stem-cells.aspx Fundamental Research ; Health & life sciences ; Cellular mechanisms ; Stem cells ; Genomics Press release ; Highlight ; Article ; Scientific result ; Success ; Focus Wed, 23 Oct 2019 10:00:00 GMT The genome of the pea assembled for the first time https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Press/2019/The-genome-of-the-pea-assembled-for-the-first-time.aspx Fundamental Research ; Science & society ; Health & life sciences ; Methodologies for life sciences ; Molecular mechanisms ; Cellular mechanisms ; Genomics Press release ; News ; Focus Tue, 03 Sep 2019 10:00:00 GMT The pea genome assembled for the first time https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2019/pea-genome-assembled-for-the-first-time.aspx ​As part of an international study, Genoscope participated in the sequencing of the garden pea genome. That work, published in Nature Genetics, will contribute to improving the agronomic characteristics of this grain legume. Agronomy ; Genomics Scientific result Tue, 03 Sep 2019 10:00:00 GMT ZNA: A new genetic support for biology and medicine https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2019/ZNA-A-new-genetic-support-biology-medicine.aspx Genoscope contributed to a study describing a novel synthesized nucleic acid with a previously undescribed molecular backbone. This new genetic support expands the biotech armamentarium for tomorrow's medicine. Genomics ; DNA Researchers ; Journalists DRF Scientific result DNA;RNA;Gene Sequence;genome;xenobiology;genomics; Fri, 09 Aug 2019 10:00:00 GMT Insights into the degradation of chlordecone in nature https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2019/Insights-into-the-degradation-of-chlordecone-in-nature.aspx Researchers from Genoscope have identified about twenty transformation products resulting from the degradation of chlordecone (a compound classed as a persistent organic pollutant) and furthermore demonstrated their presence in French West Indies soils. Metabolomics ; Remediation ; Genomics Researchers ; Journalists ; general public Jacob Highlight ; Scientific result ; News ; Scientific publications Wed, 31 Jul 2019 10:00:00 GMT Mali identified as the birthplace of domesticated African rice https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2018/Mali-identified-birthplace-domesticated-African-rice.aspx By sequencing more than 246 genomes of African rice, researchers from the François Jacob Institute of Biology and their partners have shown that the species was first domesticated 3,000 years ago in Mali. Genomics ; Health & life sciences ; Large-scale biology ; Environment ; Biodiversity Researchers ; general public ; Journalists Fontenay-aux-Roses Scientific result Mali;identification;domesticate;African;Rice; Fri, 27 Jul 2018 10:00:00 GMT The oak genome unveils the secrets of tree longevity https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Press/2018/The-oak-genome-unveils-the-secrets-of-tree-longevity.aspx Health & life sciences ; Genomics GENOSCOPE News ; Press release ; Focus Oak; Wed, 20 Jun 2018 10:00:00 GMT Pandoravirus: a giant virus and gene creator https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2018/Pandoravirus-giant-virus-gene-creator.aspx Three new species have joined the curious genus of viral giants called Pandoravirus. Both freak shows and innovators in evolution, the giant viruses continue to shake the phylogenetic tree! Biodiversity ; Genomics Researchers ; general public ; Journalists Scientific result Wed, 13 Jun 2018 10:00:00 GMT 3rd GENMED Workshop on Medical Genomics - 17th & 18th May 2018 https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2018/3rd-GENMED-Workshop-Medical-Genomics---17th--18th-May-2018.aspx The workshop on Medical Genomics aims at uniting the genomic community over two days and will include talks from GENMED partners who will present their latest results in human disease genomics. In addition, internationally renowned speakers will be invited to give general presentations covering broader and innovative topics in the field of “omic” research. Genomics Researchers Jacob Seminars GenMed;Workshop;medical genomics; Thu, 17 May 2018 06:30:00 GMT First CEA Symposium for Functional Genomics https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Other-News/2018/First-CEA-Symposium-for-Functional-Genomics.aspx The CEA held its Symposium for Functional Genomics on 4–5 April 2018 at the Fontenay-aux-Roses site. Genomics Researchers CNRGH Seminars functional genomics;Workshop; Thu, 05 Apr 2018 16:00:00 GMT The genes of domestication https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2018/genes-domestication.aspx What is the genetic "signature" of domesticated animals? Researchers from the François Jacob Institute of Biology participated in a study to shed light on that very question. Genomics ; Biodiversity Researchers ; general public ; Journalists Jacob Scientific result domesticated animals;domestication syndrome;bezoar ibex;asiatic mouflon; Wed, 07 Mar 2018 11:00:00 GMT Tara Oceans: more than 100 million genes discovered https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2018/Tara-Oceans--decouverte-de-plus-de-100-millions-de-genes.aspx The Tara Oceans expedition collected plankton samples and established a catalogue of genes and species. A new stage have been reached with the analysis of more than 100 millions of genes from complex organisms from micro algaes to small plankton animals. Biodiversity ; Genomics general public ; Researchers ; Journalists Jacob Scientific result Mon, 05 Feb 2018 08:45:30 GMT Tara Oceans: discovery of over 100 million genes from the marine world. https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Press/2018/Tara-Oceans--découverte-de-plus-de-100-millions-de-gènes-issus-du-monde-marin.aspx Continuing the analysis and exploitation of the biggest database compiled on the planktonic ecosystem, the teams from the CEA, CNRS (French National Centre for Scientific Research), EMBL (European Molecular Biology Laboratory) and the French graduate school ENS, among others[1], have just reached a new milestone by analysing the expression of over 100 million genes Health & life sciences ; Genomics Journalists ; Researchers ; general public GENOSCOPE News ; Press release ; Focus Thu, 25 Jan 2018 11:00:00 GMT First sequencing of a plant genome using nanopore sequencing https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Scientific-News/2017/first-plant-genome-sequencing-by-nanopore.aspx An international consortium, including a team from the CEA/Genoscope, carried out the complete sequencing of the genome of a tomato variety using MinION, a portable sequencer developed by Oxford Nanopore. Genomics GENOSCOPE Scientific result Tue, 24 Oct 2017 10:00:00 GMT Scientists decode the genome of Fall Armyworm: a moth pest that is invading Africa https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Press/2017/Scientists-decode-the-genome-of-Fall-Armyworm-a-moth-pest-that-is-invading-Africa.aspx Health & life sciences ; Genomics DRF Press release ; Scientific publications ; Scientific result Wed, 27 Sep 2017 10:00:00 GMT Revealed: The planktonic social network of the biological carbon pump https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Press/2016/Revealed-The-planktonic-social-network-of-the-biological-carbon-pump.aspx The network of planktonic organisms of this carbon sink has been described as a social network by an interdisciplinary team comprising oceanographers, biologists and computer experts mainly from the CNRS, UPMC, University of Nantes, VIB, EMBL and CEA. Genomics ; Environment Researchers IG Press release ; Scientific result Tue, 01 Mar 2016 11:00:00 GMT New giant virus discovered in Siberia's permafrost https://www.cea.fr/drf/ifrancoisjacob/english/Pages/News/Press/2015/new-giant-virus-discovered-in-siberia's-permafrost.aspx ​Scientists have recently discovered a new type of giant virus in the same sample of 30,000-year old Siberian permafrost from which Pithovirus had already been isolated Virus ; Genomics ; Proteomics Journalists ; Researchers Fontenay-aux-Roses Press release ; Scientific result IRTSV;Evry;microscope;IG;Fontenay;géant;virus; Wed, 09 Sep 2015 10:00:00 GMT