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To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
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News | Nanomedicine | Cancer
In the context of a collaboration with the I²BM institute, researchers from SCBM have designed micellar vectors for targeting and visual delineation of tumors.
Compact polymerized polydiacetylene-micelles with "stealth" zwitterionic surface coating were assembled and tested in a murine xenograft model of breast cancer. In vivo fluorescence imaging indicated accumulation in the tumor area and histological studies revealed predominant uptake of the micelles at the margins of the tumor, thereby allowing the delineation of its volume.
Stable and compact zwitterionic polydiacetylene micelles with tumor-targeting properties. Theodorou I, Anilkumar P, Lelandais B, Clarisse D, Doerflinger A, Gravel E, Duconge F, Doris E. 2015, 51, 14937-14940.
http://dx.doi.org/10.1039/C5CC05333A
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.