https://joliot.cea.fr/drf/joliot/en/Pages/news/Science/2024/Muscle-biomechanics-ultrasound-elastography.aspx Website of the Frédéric-Joliot Institute of Life Sciences which includes 4 departments: I2BC, DMTS, NeuroSpin and Service hospitalier Frédéric Joliot (SHFJ). The teams are mainly located at the CEA Paris-Saclay center and at the Orsay hospital. en-US https://www.cea.fr/Style%20Library/Themes/drf/instituts/images/logo-cea-joliot-2023.png https://joliot.cea.fr/drf/joliot/en https://www.cea.fr/drf/joliot/en/Pages/news/Science/2026/Auditory-environment-superior-temporal-sulcus-depth-neonatal.aspx A team from NeuroSpin investigated the impact of contrasting auditory environments on the morphology of the superior temporal sulcus (STS) in preterm newborns. By showing that exposure to music is associated with a deeper STS, the authors suggest that early auditory experience influences the structural development of temporal brain regions. Brain ; MRI ; Cognition Neurospin Scientific result ; Article Mon, 23 Feb 2026 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2026/Respiratory-dynamics-3Dspirometry-pulmonary-MRI.aspx A team from SHFJ has developed an original method of 3D spirometry using pulmonary magnetic resonance imaging in a cohort of volunteers breathing freely. This approach has revealed the existence of common patterns among individuals that depend mainly on gravity. This is a step towards a regional pathophysiological characterisation of respiratory diseases. Medical imaging ; MRI SHFJ Scientific result Mon, 12 Jan 2026 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Ketamine-TEP-synaptogenese.aspx Des chercheurs de BioMaps (SHFJ) et de MOODS ont validé une approche innovante de neuroimagerie moléculaire permettant de suivre, de manière non-invasive, les effets de la kétamine sur la densité synaptique dans un modèle préclinique de dépression. Positron Emission Tomography ; Diagnosis and innovative treatment Researchers SHFJ Scientific result préclinique;modèle animal; Mon, 22 Dec 2025 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Reconstruction-TEP-regularisation-Plug-and-Play-convergente.aspx A team of researchers from BioMaps (SHFJ) is proposing a new reconstruction method for PET imaging that combines optimization algorithms with deep neural networks. Their “plug-and-play” regularization approach ensures improved image quality thanks to PET-specific reconstruction learning, while guaranteeing stability and robustness—two critical aspects in the use of AI-based medical techniques. Positron Emission Tomography ; Artificial intelligence Researchers SHFJ Scientific result Tue, 16 Dec 2025 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/lux-eteindre-signal-IRM-sondes-micellaires--PERFECTA.aspx Researchers at the SCBM and BAOBAB have developed a new version of their nanometric micellar vector designed for fluorine-19 magnetic resonance tumor imaging. This version is intended to enhance MRI contrast by switching off the signal on demand in certain areas, while preserving it in pathological regions to be imaged. MRI ; Chemistry ; Diagnosis Researchers Neurospin Scientific result Fri, 05 Dec 2025 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Cerebral-tumour-diagnosis-passive-elastography.aspx Researchers at SHFJ and NeuroSpin applied a passive MRI elastography sequence to patients with brain tumors. This non-invasive approach provided information on tumor stiffness and nature, and could support early detection, surgical planning, and treatment monitoring. Medical imaging ; MRI ; Cancer ; Brain Neurospin Scientific result Wed, 26 Nov 2025 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Nitriles-marques-nouvelle-agent-cyanation.aspx ​Des chercheurs du SCBM en collaboration avec le SHFJ décrivent un nouveau paradigme pour le marquage isotopique au carbone de composés nitriles : plus simple, plus propre et universel, ouvrant la voie à une production élargie de molécules marquées d’intérêt en santé et en agrochimie. Chemistry ; Medical imaging Researchers SCBM Scientific result ; Europe Fri, 14 Nov 2025 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/PET-imaging-OATP-function-impacts-sex-age.aspx Researchers from BioMaps (SHFJ) investigated the hepatic activity of organic anion-transporting polypeptides (OATPs), key players in the elimination of certain drugs, using a PET imaging approach with 11C-glyburide, which revealed differences in tracer pharmacokinetics between men and women. Pharmacology ; Positron Emission Tomography ; Medical imaging SHFJ Scientific result Wed, 15 Oct 2025 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Conscience-IRM-fonctionnelle-IA.aspx Deux études récentes menées par des équipes de NeuroSpin proposent d’appliquer des méthodes combinant des modèles mathématiques d’analyse de données à l’IRM fonctionnelle pour mieux modéliser les connectivités fonctionnelles du cerveau. MRI ; Brain Researchers Neurospin Scientific result modèle animal; Thu, 09 Oct 2025 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Radioligands-TEP-neuroinflammation.aspx Des chercheurs du SHFJ, en collaboration avec le CEA-Jacob, le CRN à Lyon et le PharmaCenter à Bonn ont imaginé, synthétisé et caractérisé deux radiotraceurs TEP ciblant P2Y12, une protéine impliquée dans l’activation de la microglie durant la neuroinflammation.​ Positron Emission Tomography ; Pharmacology Researchers MIRcen Scientific result préclinique;modèle animal; Fri, 03 Oct 2025 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/GMR-sensor-biochip-for-point-of-care-diagnostics.aspx Researchers from IRAMIS and SPI (DMTS) evaluated their GMR-sensor biochip prototype for its ability to detect cancer cells in a complex medium. This approach, which combines sensor physics with medical biology, aims to develop simpler and portable diagnostic tools that meet the WHO criteria for point-of-care testing. Physics ; Biodetection SPI Scientific result ; Article Tue, 30 Sep 2025 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/PET-KinetiX.aspx A team from BioMaps, in collaboration with the Orsay mathematics laboratory, has developed PET KinetiX, software that generates parametric maps of advanced biological functions from dynamic PET images. This type of software could help accelerate the clinical transfer of these advanced PET biomarkers into clinical practice. Medical imaging Researchers SHFJ Scientific result Mon, 22 Sep 2025 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Tolerance-opioid-PET.aspx A study combining PET imaging and pharmacology, conducted by researchers at BioMaps (SHFJ), suggests that decreased availability of opioid receptors and altered neuronal energy metabolism constitute molecular signatures of opioid tolerance. These observations, made in an animal model, could help improve understanding and treatment of opioid dependence. Positron Emission Tomography ; Molecular mechanisms Researchers SHFJ Scientific result ; Article opiate;preclinical model; Wed, 06 Aug 2025 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Monitoring-microstructural-functional-brain-development-in-infants.aspx A team from NeuroSpin studied the microstructural and functional connectivity profiles of infants’ brains to understand how these characteristics evolve and relate to each other during early neurodevelopment. The results indicate that connectivity, which is altered by prematurity, strengthens with maturation, and that the associated networks become increasingly similar. Brain ; MRI ; Medical imaging Neurospin Scientific result Mon, 04 Aug 2025 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Correlation-neuroinflammation-epileptogenic-zone-TSPO-PET.aspx A study by SHFJ researchers has established a strong correlation between biomarkers of neuroinflammation, revealed by original PET imaging, and intracranial electroencephalographic recordings of epileptogenic activity. This offers hope for drug-resistant patients who are candidates for surgery. Positron Emission Tomography ; Medical imaging ; Brain SHFJ Scientific result ; Article Tue, 15 Jul 2025 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Cancer-mertansine-prodrogue.aspx Une équipe du laboratoire BioMaps, en collaboration avec l’Institut Galien Paris-Saclay a mis au point une stratégie innovante associant une prodrogue polymère et l'imagerie par tomographie par émission de positons (TEP) pour améliorer l'efficacité de la mertansine, un agent antitumoral puissant mais toxique. Medical imaging ; Diagnosis and innovative treatment ; Cancer Researchers SHFJ Scientific result ; Article préclinique;modèle animal; Tue, 01 Jul 2025 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Theranostic-antibodies-endothelin-receptors-models-glioblastoma-melanoma.aspx Researchers from SPI (DMTS) propose immunodiagnostic and immunotherapeutic approaches based on the use of innovative antibodies targeting two subtypes of endothelin receptors (ETA and ETB), recognised as relevant therapeutic targets in oncology. Health ＆ life sciences ; Cancer ; Medical imaging ; Positron Emission Tomography Neurospin Scientific result preclinical research;animal models; Thu, 22 May 2025 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/Troubles-psychiatriques-quelle-IA-pour-analyser-IRM.aspx ​​Une étude comparative menée par des chercheurs de l’UMR BAOBAB/NeuroSpin en collaboration avec le LTCI (Télécom Paris) explique pourquoi l’apprentissage profond est plus performant que l’apprentissage automatique standard en neuroimagerie et souligne le potentiel de l’apprentissage par transfert.​ MRI ; Artificial intelligence Scientific result ; Article Thu, 27 Feb 2025 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2025/antenne-lobes-temporaux.aspx Une équipe de NeuroSpin en collaboration avec Multiwave Technologies a conçu et développé une antenne de réception pour l’IRM Iseult 11,7 T ciblant uniquement les lobes temporaux, une région d’intérêt pour les neuroscientifiques. MRI Researchers Neurospin Scientific result ; Europe ; Article Thu, 30 Jan 2025 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/QSM4SENIOR-cartographie-charge-en-fer-vieillissement-cerveau.aspx Les premières données du projet QSM4SENIOR, porté par des équipes de NeuroSpin et de la société VENTIO, ont été publiées dans Frontiers in Neuroimaging. Elles permettent de dresser une cartographie très précise de l’évolution de la charge en fer au cours du vieillissement cérébral normal, une aide précieuse pour les scientifiques spécialistes des maladies neurodégénératives. ​ Brain ; MRI Researchers Neurospin Scientific result ; Europe ; Industrial partnerships Tue, 26 Nov 2024 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/QSM4SENIOR-Iron-mapping.aspx The first data from the QSM4SENIOR project, led by teams from NeuroSpin and VENTIO, have been published in Frontiers in Neuroimaging. They provide a highly accurate map of changes in iron levels during normal brain ageing, a valuable aid for scientists specialising in neurodegenerative diseases. Brain ; MRI Researchers Neurospin Scientific result ; Europe ; Industrial partnerships Tue, 26 Nov 2024 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/Chimpanzee-and-human-brain-superficial-structural-connectivities.aspx A team from NeuroSpin has proposed a classification of the morphology of short white matter bundles (SWMBs) in human and chimpanzee brains. A wide variety of shapes was observed, as well as differences. This study provides valuable information on SWMB morphology and its potential implications for human cognitive development Brain ; Evolution ; MRI Neurospin Scientific result animal sciences; Fri, 22 Nov 2024 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/IBC3-mapping-cognitive-functions-naturalistic-stimuli.aspx Several NeuroSpin researchers have taken part in the Individual Brain Charting (IBC) project, aimed at creating a precise map of the cognitive functions of the human brain. In this third phase, they are using the Fast Shared Response Model to analyze large-scale fMRI data and model responses to natural stimuli involving the visual, auditory and language systems. MRI ; Brain ; Cognition Neurospin Scientific result ; Article Wed, 30 Oct 2024 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/Iseult-apres-images-la-publication-scientifique.aspx L’équipe de NeuroSpin en charge de l’acquisition des premières images de cerveau de volontaires à 11,7 teslas a publié dans Nature Methods les détails de son protocole d’étude exploratoire menée à ce champ magnétique inégalé. Brain ; MRI Researchers Neurospin Scientific result ; Article Mon, 28 Oct 2024 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/neuromodulatory-nuclei-Alzheimer-and-related-disorders.aspx A team from GHU Paris and SHFJ has used brain MRI to study the integrity of the locus coeruleus and nucleus basalis of Meynert in patients with early-onset Alzheimer's disease (AD), age-related TDP-43 encephalopathy (LATE) and fronto-temporal dementia (FTD). Both structures are altered in early AD, LATE and probably FTD, making these neuromodulatory areas potential therapeutic targets Diseases ; Brain ; Cognition ; MRI ; Positron Emission Tomography ; Alzheimer's disease Neurospin Scientific result Wed, 16 Oct 2024 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/PET-image-reconstruction-deep-learning-clearmind-detector.aspx Three DES and DRF laboratories have developed an innovative Machine Learning algorithm to improve the reconstruction of PET images acquired as part of the ClearMind project, a technology based on the detection of gamma photons by a monolithic lead tungstate crystal detector. A step towards more accurate PET imaging Positron Emission Tomography ; Methodologies for life sciences ; Artificial intelligence Irfu Scientific result Mon, 07 Oct 2024 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/Functional-brain-connectivity-emotional-states-bipolar-disorder.aspx A study conducted by NeuroSpin researchers reveals abnormalities in functional brain connectivity in the sub-nucleus region of the amygdala (emotion center), in patients with bipolar disorder. These anomalies, which depend on whether the patient is depressed or manic, are potential biomarkers of interest. Brain ; MRI ; Cognition ; Diseases Neurospin Scientific result Mon, 30 Sep 2024 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/PET-monitoring-central-effects-innovative-smoking-cessation-therapy.aspx A BioMaps team has used PET imaging to monitor glucose metabolism as a marker of the cerebral impact of smoking cessation, as well as the effects of a promising drug-candidate for the treatment of such cessation. By revealing the restoration of normal activity in the brain area associated with craving, these results offer hope for smoking cessation in humans Positron Emission Tomography ; Medical imaging ; Pharmacology ; Brain SHFJ Scientific result Preclinical;animal models;murine model; Thu, 29 Aug 2024 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/Marquage-echange-isotopique-soufre.aspx Une équipe du SCBM met au point une méthode d’échange isotopique du soufre pour le marquage de molécules biologiquement actives. Telle une plateforme isotopique multi-échangeable, le procédé permet également un échange isotopique du carbone et d’hydrogène donnant accès à un grand nombre d’isotopologues. L’équipe met en avant le potentiel de la méthode pour vérifier l’authenticité de molécules organiques commerciales. Chemistry ; Diagnosis and innovative treatment ; Medical imaging Researchers SCBM Scientific result Tue, 09 Jul 2024 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/Correlation-structure-cerebellum-cognitive-functions.aspx A collaborative study led by NeuroSpin researchers analyzed anatomical MRI images of 662 young subjects from the Healthy Brain Network cohort, to map different features of cognitive function linked to cerebellar structure. It shows that there is a complex association between key cognitive functions and particular lobules of the cerebellum. Brain ; Cognition ; MRI Neurospin Scientific result Fri, 05 Jul 2024 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Institute/2024/NOMATEN-training.aspx As a stakeholder in the NOMATEN Centre of Excellence for innovative multifunctional materials, the CEA-Joliot Institute supports its development by regularly organizing training sessions for its staff. The latest examples. Medical imaging ; Radioactivity ; Materials Academic partnerships ; Europe ; Article Fri, 05 Jul 2024 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/Muscle-biomechanics-ultrasound-elastography.aspx A team from BioMaps (SHFJ) measures for the first time the in vivo local mechanical properties at play in a muscle (elasticity, anisotropy, non-linearity) using a non-invasive method, ultrasonic shear wave elastography. The originality of the approach lies in its ability to perform such measurements in a so complex tissue. Medical imaging ; Physics SHFJ Scientific result Fri, 14 Jun 2024 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/disulphide-bridge-radiolabeling.aspx Researchers at BioMaps have developed a "re-bridging agent" for the radiolabelling of biomolecules containing disulphide bridges. Their strategy has enabled several molecules of therapeutic interest to be labelled with fluorine-18, copper-64 and zirconium-89. Chemistry ; Diagnosis and innovative treatment ; Medical imaging Researchers SIMOPRO Scientific result ; Article Fri, 24 May 2024 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/Response-intra-tumoral-immunotherapy-by-immunoPET.aspx A team from BioMaps (SHFJ), in partnership with the Gustave Roussy Institute, has used immunoPET imaging to assess the influence of tissue distribution on the efficacy of cancer immunotherapy, administered intra-tumor and intravenously in mice. Intratumoral administration is more effective and reduces overall exposure of organs at risk Medical imaging ; Positron Emission Tomography ; Cancer SHFJ Scientific result preclinical research;animal models; Fri, 19 Apr 2024 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Press/2024/world-premiere-living-brain-imaged-with-unrivaled-clarity-thanks-to-world-most-powerful-MRI-machine.aspx ​The CEA is revealing a series of in vivo human brain images acquired with the Iseult MRI machine and its unmatched 11.7 teslas magnetic field strength. This success is the fruit of more than 20 years of R&D as part of the Iseult project, with one pillar goal being to design and build the world’s most powerful MRI machine. Its ambition is to study healthy and diseased human brains with an unprecedented resolution, allowing us to discover new details relating to the brain’s anatomy, connections, and activity. Health ＆ life sciences ; Brain ; Medical imaging ; Neurodegenerative diseases ; Cognition Journalists ; Institutions ; general public ; Researchers ; Young people ; Companies Irfu Press release Tue, 02 Apr 2024 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/Neurodevelopmental-model-prediction-psychotic-transition.aspx A NeuroSpin team has built a predictive model for the onset of psychosis using a combination of supervised learning analyses and a model of neuroanatomical age, based on neuroimaging data from healthy subjects and those at risk of psychotic transition. MRI ; Diseases ; Artificial intelligence ; Brain Neurospin Scientific result Thu, 21 Mar 2024 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/Methodological-developments-emergence-ultra-high-field-MRI.aspx Researchers at NeuroSpin have recently published 3 articles in Magnetic Resonance in Medicine on their technological and methodological developments that will help meet the challenges of ultra-high field MRI for tomorrow's medical brain imaging. MRI ; Technologies Neurospin Scientific result Mon, 19 Feb 2024 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/First-complete-atlas-chimpanzee-brain-connectivity.aspx NeuroSpin researchers map chimpanzee brain structural connectivity for the first time using diffusion MRI data. New image processing enabled them to create two atlases of deep and superficial white matter connectivity. A step towards a better understanding of the evolution of the hominid brain. Brain ; MRI ; Computing Neurospin Scientific result préclinique; Mon, 12 Feb 2024 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2024/elasticity-biomarker-biological-tissue-diagnostics.aspx SHFJ researchers have validated the use of a new biomarker, the nonlinear shear modulus, to measure the elasticity of biological tissues, by comparing results obtained using echography with those obtained using MRI imaging and digital simulation. This biomarker is of particular interest for the diagnosis of certain breast cancers. Medical imaging ; MRI ; Diagnosis SHFJ Scientific result Wed, 24 Jan 2024 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/Impact-metabolism-PET-imaging-neuroinflammation.aspx Researchers at BioMaps evaluated the effect of several factors on the distribution of [18F]DPA-714 in 201 subjects who participated in SHFJ PET imaging protocols to better understand the role of neuroinflammation in various neurological diseases. They conclude that measures of individual metabolism are important in image interpretation. Positron Emission Tomography ; Medical imaging ; Pharmacology SHFJ Scientific result Thu, 12 Oct 2023 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/IRM-effets-transitoires-UHF-systeme-vestibulaire.aspx Des chercheurs de NeuroSpin, en collaboration avec NeuroPSI montrent que l’effet des ultra hauts champs magnétiques sur l’appareil vestibulaire de souris est transitoire. MRI Researchers Neurospin Scientific result ; Article cochlée; Fri, 06 Oct 2023 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/Relationship-cerebellar-structure-social-abilities-young-autistic.aspx A collaborative study by NeuroSpin researchers, using anatomical MRI data and a dimensional approach in 850 subjects from the Healthy Brain Network cohort, shows how the social skills of these children and adolescents are linked to the structure of their cerebellum Brain ; Cognition ; MRI Neurospin Scientific result Tue, 12 Sep 2023 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Events/2023/Kick-off-meeting-MIND.aspx ​​​Le 07 septembre, l'équipe MIND organisait son kick-off meeting, symbolisant la volonté commune de sestutell es, CEA et Inria, de consolider et de créer des synergies en intelligence artificielle et machine learning pour les neurosciences. MRI ; Artificial intelligence ; Brain Researchers ; Institutions Neurospin Inauguration ; Colloquium deep learning;Deep Neural Network;réseaux de neurones; Mon, 11 Sep 2023 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Institute/2023/Kick-off-meeting-MIND.aspx On 07 September, the young MIND team organised its kick-off meeting, symbolising the shared desire of its two supervisory administrations, the CEA and Inria, to consolidate and create synergies in artificial intelligence and machine learning for neuroscience. MRI ; Artificial intelligence ; Brain Researchers ; Institutions Neurospin Inauguration ; Colloquium deep learning;Deep Neural Network; Mon, 11 Sep 2023 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/PET-imaging-antibody-endothelin-receptors-glioblastoma-tumors.aspx Researchers at BioMaps (SHFJ) and SPI (DMTS) have studied the pharmacokinetics of a novel immuno-radioligand targeting the endothelin A receptor (ETA), overexpressed in many cancers, particularly glioblastoma. The immunoPET imaging approach used in this study in a preclinical model confirms the theranostic potential of this antibody. Positron Emission Tomography ; Cancer ; Medical imaging Neurospin Scientific result Thu, 07 Sep 2023 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/IA-IRM-haut-champ-multiples-pistes-equipe-MIND.aspx Brain ; MRI ; Artificial intelligence Researchers Neurospin Scientific result ; Patent Wed, 30 Aug 2023 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/Longitudinal-monitoring-tauopathy-PET-imaging.aspx A joint team from GHU Paris and BioMaps (SHFJ) conducted a 2-year longitudinal study of 27 people with Alzheimer's disease, tracking the progression of tau pathology measured by PET imaging, of cortical atrophy using MRI, and their links with cognitive decline. Alzheimer's disease ; Medical imaging ; MRI ; Positron Emission Tomography SHFJ Scientific result ; Article Wed, 02 Aug 2023 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/rabbit-motif-PET-imaging-diagnostic-evaluation-parkinsonian-syndromes.aspx BioMaps researchers compared the diagnostic performance of the rabbit visual pattern observed in 18F-DOPA PET imaging with the standard procedure approved by the international nuclear imaging societies for the diagnosis of parkinsonian syndromes in PET/MRI and obtained encouraging results, which may validate the clinical utility of such a model Positron Emission Tomography ; Medical imaging ; Parkinson's disease ; Brain SHFJ Scientific result Tue, 23 May 2023 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/Mise-en-exploitation-IRM-11-7-T-Iseult.aspx La mise en exploitation de l’IRM 11.7 T Iseult en 2021 a couronné près de 20 ans de recherche et développement du CEA. Dans un article publié dans le journal Magnetic Resonance Materials in Physics, Biology and Medecine, Nicolas Boulant et Lionel Quettier, chefs du projet Iseult pour les instituts Joliot et Irfu du CEA, passent en revue les détails de cette mise en service. MRI ; Brain Article Fri, 28 Apr 2023 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/Radiomarquage-crizotinib-fluor-18-nouvel-outil-TEP.aspx Des chercheurs du SHFJ ont mis au point la radiosynthèse au fluor-18 du crizotinib, un médicament qui ne pénètre pas dans le cerveau. Ce nouvel outil pour l’imagerie TEP permettra d’explorer de futures stratégies visant à faire passer la barrière hémato-encéphalique à ce médicament pour traiter certaines métastases cérébrales. Positron Emission Tomography ; Cancer ; Diagnosis and innovative treatment Researchers SHFJ Scientific result ; Article Thu, 27 Apr 2023 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/Structuring-neuroanatomical-criteria-fetal-alcohol-spectrum-disorder.aspx By analyzing brain imaging data, researchers from InDEV (NeuroSpin / UMR NeuroDiderot) have identified recurrent abnormalities in subjects with fetal alcohol syndrome, the combination of which could have a particularly interesting diagnostic value for non-syndromic forms of fetal alcohol spectrum disorders. MRI ; Diagnosis and innovative treatment Researchers Scientific result Mon, 13 Mar 2023 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/Genetic-variations-regulatory-regions-morphology-brain-sulci.aspx Using UK Biobank imaging-genetics data, a collaborative study led by NeuroSpin found that variation in genomic regions, known as enhancers, could affect the morphology of cortical sulci and be associated with the evolution of locomotion in primates and bipedalism in our hominin ancestors. MRI ; Genomics ; Brain Neurospin Scientific result Mon, 27 Feb 2023 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/Nanoparticles-to-improve-radiotherapy.aspx Researchers from the SHFJ laboratory at ISMO have demonstrated the value of platinum nanoparticles as potential radiosensitizing agents for radiation therapy. Diagnosis and innovative treatment ; Positron Emission Tomography Researchers SHFJ Scientific result Radiotherapy;biodistribution;platinum nanoparticles; Tue, 21 Feb 2023 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/New-radiolabeling-strategy-immunoTEP.aspx Researchers from the BioMaps laboratory (SHFJ) and the Molecular Engineering for Health Service (SIMoS, DMTS) developed an enzymatic approach for radiofluorination of an anti-PD-L1 Fab and compared its in vivo properties to the same Fab stochastically labeled by two conventional methods. Diagnosis and innovative treatment ; Positron Emission Tomography Researchers SHFJ Scientific result PD-L1;radiomarquage;lipoate-protéine ligase;radiofluoration; Tue, 21 Feb 2023 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/Glioblastoma-FUS-cetuximab.aspx Researchers from the SHFJ, in collaboration with NeuroSpin, show that the use of focused ultrasound does not increase the therapeutic effects of cetuximab on glioblastoma although the opening of the blood-brain barrier is transiently effective. Positron Emission Tomography ; Diagnosis and innovative treatment Researchers Neurospin Scientific result Wed, 15 Feb 2023 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2023/Anatomical-atypia-cerebellum-autistic-people.aspx By studying the morphology of the cerebellar gray matter, an international consortium coordinated by NeuroSpin researchers concludes that there are no anatomical atypia in the cerebellum of people with autism. Diseases ; Brain ; Medical imaging Researchers Saclay Scientific result IRM 3T;TDAH; Mon, 06 Feb 2023 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/SNR-high-field-MRI.aspx ​A collaboration led by a METRIC team (BAOBAB/NeuroSpin) has undertaken to measure the signal-to-noise ratio (SNR) in MRI at the centre of a spherical phantom at different magnetic field strengths (B0). Their data confirm the theories that SNR increases with approximately the square of B0. MRI Researchers Neurospin Scientific result ; Article Thu, 17 Nov 2022 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/CEST-linescan-Etudier-des-metabolites-peu-concentres-dans-cerveau.aspx NeuroSpin researchers, in collaboration with Iramis and the Università Statale di Milano, have developed a CEST magnetic resonance spectroscopy sequence that allows them to detect and confirm the presence of three dipeptides in the brain and skeletal muscle of adult rats and thus to consider future studies of their physiological role. MRI ; Cell and molecular imaging Researchers Neurospin Scientific result Tue, 15 Nov 2022 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/Specificity-of-reading-and-face-recognition-cerebral-circuits.aspx By measuring fMRI responses to written words, faces, houses and checkerboards in three groups of children, pre-readers and beginning readers aged 6 and advanced readers aged 9, a team from UNICOG (NeuroSpin) shows that reading acquisition recycles and specializes a pre-existing but plastic visual circuit connected to language areas. Brain ; MRI ; Learning Neurospin Scientific result Mon, 12 Sep 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/Predicting-cognitives-activities-fMRI-maps.aspx A NeuroSpin team succeeded in decoding a large set of human mental processes by training neural networks to predict cognitive labels from a cognitive atlas and by leveraging the data set of NeuroVault, a web-based database for collecting and sharing statistical maps of the human brain. Brain ; Cognition ; MRI ; Artificial intelligence Neurospin Scientific result Thu, 30 Jun 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/fluorine-18-thiol-labeking-biomolecules-TEP.aspx Radiochemists from the BioMaps unit (SHFJ) have developed and automated the synthesis of an 18F-fluoropyridine containing a thiol function (-SH), allowing its conjugation to model biomolecules within 45 minutes. A step towards rapid radiolabeling of complex biological molecules for PET imaging. Radioactivity ; Chemistry ; Positron Emission Tomography SHFJ Scientific result Tue, 28 Jun 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/Pads-dielectriques-IRM-tres-haut-champ.aspx To address the problem of ultre high field MRI signal loss in certain regions of the human body, a collaboration involving the CEA-Joliot, the CEA-Iramis, the Fresnel Institute and Multiwave Imaging has led to the development of a new generation of simple and inexpensive silicon carbide-based pads. The new composition makes the pads invisible to MRI and prolongs their performance when compared to existing solutions. MRI Researchers ; Partners Iramis Scientific result ; Article specific absorption rate;radiofrequency passive shimming;shims; Tue, 07 Jun 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/First-atlas-anatomical-brain-connectivities-quail.aspx The expertise of NeuroSpin in diffusion MRI has allowed to establish the first atlas of the anatomical connectivities of the Japanese quail brain at a resolution of 150 m in three dimensions. MRI ; Brain Researchers Neurospin Scientific result ; Article Tue, 31 May 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/Shape-early-brain-sulcus-predict-pathologies.aspx Neurospin researchers conducted a longitudinal brain imaging study in very premature infants to analyze the variability of the shape of the central sulcus early in its development and its functional implications. Brain ; MRI Researchers Neurospin Scientific result brain fold;gyrification;prematurity;hemispheric asymmetry; Fri, 20 May 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/Segmentation-rare-brain-tumors.aspx A study led by NeuroSpin researchers proposes an optimized delineation of rare brain tumors, based on a combined approach of object detection and deep learning segmentation in tumor images, a key step in the characterization of cancers. Brain ; Medical imaging ; MRI Neurospin Scientific result ; Article Thu, 05 May 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/MRI-3D-sparkling.aspx NeuroSpin researchers propose a new version of their compressed MRI acquisition algorithm, SPARKLING, extended to 3D imaging. Their method reduces acquisition time by a factor of 20 for T2*-weighted scans without compromising image quality. Simulation ＆ modelling ; MRI Researchers Neurospin Scientific result ; Europe Thu, 28 Apr 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/Radioligands-immunoPET-PD-1-PD-L1.aspx Researchers from the SHFJ and the DMTS have developed optimized radioligands for immunoPET imaging. The objective is to better predict the effectiveness of anti-PD1/anti-PDL1 immunotherapy used to fight certain cancers. Positron Emission Tomography ; Cancer Researchers SIMOPRO Scientific result programmed cell death-ligand 1; Tue, 12 Apr 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/Deuterated-tritiated-molecules-more-dversity.aspx Researchers from the SCBM describe a hydrogen isotope labeling process that is easy to implement and whose starting point is a "simple" mixture, in a solvent, of the product to be labeled with a pre-catalyst. Explanations of this process which finds applications in many fields including drug development or medical imaging. Chemistry ; Diagnosis and innovative treatment ; Medical imaging Researchers SCBM Scientific result marquage isotopique;biomolécule;activation C-H;ADME-DMPK; Wed, 06 Apr 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/PET-MRI-imaging-epilepsy-detection.aspx A team from BioMaps (SHFJ), in collaboration with several hospital groups, shows that hybrid PET/MRI imaging significantly improves the detection of epileptogenic foci and, consequently, the outcome of surgical treatment of epilepsy. Medical imaging ; Positron Emission Tomography ; MRI SHFJ Scientific result Tue, 05 Apr 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/Alzheimer-Tau-PET-imaging.aspx A joint team from GHU Paris and SHFJ shows the predictive value of PET imaging data of the Tau protein in the progression of Alzheimer's disease. Alzheimer's disease ; Positron Emission Tomography Researchers SHFJ Scientific result ; Press release radiotracer; Sun, 03 Apr 2022 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/thalamus-DBS-signatures-conscience.aspx Using fMRI and EEG, NeuroSpin and ICM researchers show that deep brain stimulation of the central part of the thalamus restores the richness of brain activity specific to consciousness, which is "switched off" in an anesthetized non-human primate. This work paves the way for clinical studies in patients with consciousness disorders. Cognition ; MRI Researchers Neurospin Scientific result Sat, 26 Mar 2022 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Institute/2022/QSM4SENIOR.aspx The QSM4SENIOR project, led by NeuroSpin and the company VENTIO, aims at developing an original early biomarker of aging by using data from the SENIOR study of NeuroSpin. QSM4SENIOR has just been funded by the EOSC-Life. Brain ; MRI Researchers ; Institutions Neurospin Europe ; Industrial partnerships Wed, 02 Mar 2022 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/Genetic-architecture-language-functional-connectivity.aspx Using data from the UK Biobank, the world's largest general population imaging-genetics cohort, a collaboration led by a team at BAOBAB (NeuroSpin) has identified genes involved in the genetic architecture of language functional connectivity. These genes could be a priority for studying natural language. Brain ; MRI ; Cognition ; Genomics Neurospin Scientific result Mon, 14 Feb 2022 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2022/tSNR-optimization-functional-MRI.aspx A NeuroSpin team (BAOBAB) has tested a signal denoising method dedicated to very high field (7T) functional MRI. It is based on the weighted combination of images from each reception channel of the radio frequency coil, a combination that optimizes the stability of the signal over time. MRI ; Physics Neurospin Scientific result ; Article Thu, 27 Jan 2022 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2021/PET-MRI-imaging-tumors-supervoxel-level.aspx A collaborative study led by BioMaps researchers (SHFJ) demonstrates that fully integrated quantitative multiparametric analysis of non-small cell lung cancer in hybrid 18F-FDG PET/MRI 3T imaging is clinically feasible and could enable biological characterization of tumors at the supervoxel scale. Medical imaging ; Positron Emission Tomography ; MRI ; Cancer Scientific result Wed, 10 Nov 2021 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2021/Amyloid-tau-imaging-diagnosis-progressive-amnesia.aspx Researchers from BioMaps (SHFJ) and the Service de Neurologie de la Mémoire et du Langage (Hôpital Ste-Anne) show, through amyloid and tau molecular imaging in patients followed for 2 years, that the diagnosis of progressive amnesia in the elderly is not necessarily Alzheimer's disease and may be caused by other mechanisms clearly distinguishable from it. Positron Emission Tomography ; Medical imaging ; Alzheimer's disease Scientific result Thu, 04 Nov 2021 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Press/premieres-images-irm-iseult-2021.aspx September 2021, the 11.7 Tesla MRI of the Iseult project, the most powerful in the world for human imaging, has just unveiled its first images. Health ＆ life sciences ; Brain ; Physics Journalists ; general public ; Researchers ; Partners Neurospin News ; Press release ; Découvertes et avancées Brain;MRI;neuroanatomy;Iseult;supra; Thu, 07 Oct 2021 05:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2021/Disentangle-neuro-vasc-BOLD.aspx Researchers at NeuroSpin have developed a deconvolution method to estimate from BOLD fMRI data the coupling between neuronal activity and blood flow, the characteristic signals of neuronal activity and the associated brain areas. The work was published in NeuroImage. MRI ; Simulation ＆ modelling Researchers SHFJ Scientific result BOLD signal;multivariate modeling;sparsity;dictionary learning; Tue, 14 Sep 2021 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2021/Singlet-Fission-Plants-Carotenoids.aspx Researchers from I2BC (CEA-Joliot/CNRS/UPSay, in collaboration with the JP Bourgin Institute and the University of Vilnius, decipher for the first time the energy dissipation process called "singlet fission" in two natural flower carotenoids, a fundamental mechanism for the design of new and more efficient multi-electron photocatalysts. Solar energy ; Photosynthesis ; Quantum Physics Scientific result Mon, 30 Aug 2021 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2021/diffusion-MRI-characterizes-radiation-induced-neurological-impairments.aspx A team comprising iRCM (CEA-Jacob) and NeuroSpin (CEA-Joliot) researchers analyzed the consequences of irradiation on brain development and neurogenesis in a preclinical model. That work, published in Radiation Research, lays a path for the use of diffusion imaging for the early detection of neurological abnormalities resulting from different types of stress. Brain ; Impacts on living (organisms) ; MRI ; Biomarkers ; Radiobiology Researchers ; Journalists ; general public DRF Scientific result ; Highlight ionizing radiations;Brain;neurodevelopmental disorder;neurogenesis;MRI;structural MRI;diffusion MRI; Thu, 24 Jun 2021 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2021/PETimaging-neuropharmacology-buprenorphine.aspx Researchers at BioMaps (SHFJ) have succeeded in determining the interaction dynamics of buprenorphine, an opioid drug with a particularly complex pharmacology, with its brain receptors in vivo. To do so, they developed an original PET imaging approach based on the use of the radiolabeled molecule (11C-buprenorphine). Brain ; Positron Emission Tomography ; Pharmacology Scientific result Wed, 05 May 2021 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2021/WIKIBrainStem.aspx The Ginkgo team (BAOBAB / NeuroSpin), in collaboration with the Inserm iBRAIN U1253 unit (Tours), published in NeuroImage the first anatomical atlas of the human brainstem with at mesoscopic scaleresolution from extreme ultra-high field MRI. Freely available as a wiki, this atlas will be used in particular by neuroanatomists and neurosurgeons. MRI Researchers Neurospin Scientific result ; Europe brainstem;Anatomy; Wed, 28 Apr 2021 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2021/Brain-sulci-imaging-and-genetics.aspx Researchers from NeuroSpin and CNRGH (Jacob Institute) have studied, on a genome-wide scale, the potential associations of haplotypes (set of variants located side by side on a chromosome) with the opening value of imaged brain sulci, indicator of brain aging, from the UK Biobank neuroimaging-genetics cohort. MRI ; Genomics ; Brain Scientific result Mon, 19 Apr 2021 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2021/Micellar-probe-fluorine-MRI-tumor.aspx A SCBM (DMTS) team, in collaboration with researchers at NeuroSpin and I2BC, is describing micellar nanometric vectors targeting tumors that have been imaged by fluorine magnetic resonance imaging (MRI). The observed 19F signal made it possible to precisely delimit the volume of the tumor zone in a mouse model and to quantify the probe accumulated in the target tissue. Chemistry ; Nanomedicine ; Cancer ; MRI Scientific result Thu, 04 Mar 2021 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Institute/2021/Towards-transcranial-echography.aspx Jean-Luc Gennisson (BioMaps/SHFJ) coordinated, in partnership with the CEA-List (Sylvain Chatillon), the EchoBrain project (ATTRACT/H2020) aimed at adapting the digital tools developed by the List (CIVA platform) to significantly increase the quality of brain echography images, simple alternative compared to the methods (MRI, X-ray scanner) currently used for the diagnosis of strokes. Brain ; Medical imaging ; Simulation ＆ modelling News ; Article Tue, 19 Jan 2021 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Institute/2021/Launch-of-AROMA.aspx AROMA, a FET-Open H2020 project, aims to develop the methodology necessary for the optimal operation of the future 11.7 T MRI being installed at NeuroSpin. This 5-year project, coordinated by Nicolas Boulant (NeuroSpin), with an overall budget of 3.6 million euros, involving six partners from five countries representing academia and industry, started on January 1, 2021. Methodologies for life sciences ; Brain ; MRI News Wed, 06 Jan 2021 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2020/Facebook-challenge-IA-CEA-researchers-2d.aspx In the field of artificial intelligence, international competition is tough. So when researchers from CEA-Joliot and Irfu challenge start-ups and other companies specializing in AI, we cheer them on. Here’s a success story from the field of MRI reconstruction. MRI ; Artificial intelligence Researchers Neurospin Success Fri, 11 Dec 2020 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2020/Atypical-cerebral-organization-for-language.aspx Researchers from the Neurofunctional Imaging Group (GIN, NeuroSpin, Bordeaux) studied by functional MRI, the organization of the brain network of sentence processing in individuals "atypical" for language, i.e. with a major role of the right hemisphere. Brain ; MRI Scientific result Wed, 09 Dec 2020 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2020/Psychotic-symptoms-poor-information-diffusion-in-brain.aspx A collaborative study by NeuroSpin suggests that psychosis and impaired conscious access may be closely related phenomena. MRI Researchers Neurospin psychiatry;diffusion MRI;dMRI; Tue, 08 Dec 2020 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Institute/2020/Bruno-Robert-awarded-Honoris-causa-Professor-Vilnius.aspx This appointment comes after more than 15 years of close scientific collaboration between Bruno Robert's team in CEA Paris-Saclay and the Physics Department of the University of Vilnius. Quantum Physics ; Photosynthesis News ; Article Thu, 19 Nov 2020 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2020/thermometry-MRI.aspx Researchers at NeuroSpin are proposing a new magnetic resonance thermometry method to increase the accuracy in the measurement of small temperature variations induced by MRI. MRI ; Methodologies for life sciences Researchers Neurospin Scientific result MR thermometry;ultra high field; Wed, 18 Nov 2020 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2020/Double-ceramic-probe-magnetic-resonance-microscopy.aspx Researchers from the M-CUBE european consortium, together with a team from NeuroSpin, are demonstrating the possibility of imaging two samples by 17.2 T magnetic resonance microscopy (NeuroSpin imager), at a single acquisition time, using two coupled ceramic resonators (probes) that lead to a better signal-to-noise ratio compared to reference MRI probes. MRI ; Physics Scientific result ; Article Mon, 26 Oct 2020 11:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2020/Analysis-multitask-functional-MRI-data-IBC.aspx In this study, NeuroSpin researchers leveraged the Individual Brain Charting (IBC) dataset, acquired by high-resolution functional MRI during the performance of behavioural tasks, to investigate the feasibility of individual mapping of the cognitive components underlying the tasks. They thus individualized six regions of interest in the language network and established their cognitive profile. MRI ; Cognition Scientific result Thu, 08 Oct 2020 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2020/ImmunoPET-BBB-Ab.aspx Researchers from SHFJ, NeuroSpin and DMTS have demonstrated, by immunoPET imaging, the impact of transient BBB permeabilization on brain exposure to an anti-EGFR antibody. Promising prospects for targeted immunotherapy of glioblastoma. Cancer ; Medical imaging ; Positron Emission Tomography SIMOPRO Scientific result radiomarquage;zirconium;IRM; Tue, 06 Oct 2020 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2020/Functional-neuroanatomy-number-processing.aspx NeuroSpin researchers used ultra-high field (7 Tesla) functional magnetic resonance imaging (fMRI) to better localize the processing and manipulation of numbers in the human brain. The results, which enrich our understanding of the functional organization of the intra-parietal sulcus, the cerebral center of digitization, are published in NeuroImage. Brain ; MRI ; Cognition ; Mathematics Scientific result Wed, 23 Sep 2020 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Press/mri-antenna-brain.aspx The European Commission once more places its trust on Multiwave company and its partners, Aix-Marseille Université , CEA and Université Catholique de Louvain to revolutionize ultra-high field magnetic resonance imaging of the brain. Health ＆ life sciences ; Brain ; Methodologies for life sciences ; Medical imaging ; MRI Journalists ; Institutions ; Companies Neurospin News ; Focus NeuroSpin;DRF;Europe;MRI;Brain;project;Joliot;antenna;imagery; Tue, 22 Sep 2020 08:06:13 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Institute/2020/Florent-Meyniel-ERC-SG.aspx On September 3, the European Research Council announced the names of the 436 winners of the ERC Starting Grant 2020 call. Florent Meyniel, CEA researcher at the NeuroSpin department of the Joliot Institute, is among them. MRI Neurospin Prizes and awards ; Europe ; Article H2020;Bayes; Thu, 03 Sep 2020 10:05:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2020/SENIOR-cohort-cerebral-aging.aspx The SENIOR study, conducted by several NeuroSpin teams, consists in monitoring, since March 2012, a cohort of 100 subjects aged 50 to 70 years by annual MRI imaging over a period of 10 years, to establish a normal aging brain imaging biomarkers mapping. This publication in Alzheimer's Research & Therapy describes the baseline experimental protocol and presents first promising results. Neurodegenerative diseases ; Brain ; MRI ; Positron Emission Tomography Scientific result Tue, 04 Aug 2020 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2020/Multimodal-imaging-quantify-biliary-drug-excretion.aspx Researchers from the BioMaps unit based at the SHFJ have developed an imaging protocol to study in vivo the hepatobiliary transport capacity responsible for the elimination of many drugs and to better understand the hepatotoxicity of certain drugs. Medical imaging Researchers SHFJ Scientific result technetium-99m;liver;scintigraphy; Thu, 02 Jul 2020 10:00:00 GMT https://www.cea.fr/drf/joliot/en/Pages/news/Science/2020/diffusionMRI-astrocyte-activity.aspx In two articles published in PLoS ONE, researchers at NeuroSpin show that diffusion MRI can monitor astrocyte activity in the brain in a non-invasive way, allowing a better understanding of its involvement in the glymphatic system and in functional MRI. MRI ; Brain Neurospin Scientific result BOLD MRI;functional MRI;aquaporins;diffusion MRI; Thu, 11 Jun 2020 10:00:00 GMT