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The French Alternative Energies and Atomic Energy Commission (CEA) is a key player in research, development and innovation.
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Press release | Scientific publications | Gene and cell therapy | Genetic diseases | Diagnosis and innovative treatment | Health ＆ life sciences
A team led by Pr. Marina Cavazzana conducted at Necker Children's Hospital, AP-HP and the Imagine Institute (AP-HP / Inserm / Université Paris Descartes) in October 2014 gene therapy in the context of a phase I clinical trial / II in a patient 13 years with severe sickle cell disease. Conducted in collaboration with Pr. Philippe Leboulch (CEA / University Faculties of Medicine of Paris-Sud and Harvard University) who developed the vector used and directed preclinical studies, this innovative treatment allowed complete remission of clinical signs of disease and correction of biological signs. The results are published on March 2nd 2017 in the New England Jounal of Medicine.
Gene Therapy in a Patient with Sickle Cell Disease ; N Engl J Med 2017; 376: 848-855 March 2, 2017 DOI: 10.1056 / NEJMoa1609677
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.