Cancer Biology and Infection laboratory researchers study the mechanisms involved in the stability / degradation of mRNA of the HIF-1 protein. This protein is regulated by hypoxia in tumors rapidly proliferating. Because HIF-1 induces the transcription of the major gene for angiogenesis, VEGF, this study will contribute to a better understanding of the mechanisms of tumor angiogenesis and therapeutic applications in the treatment of cancer.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.