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Iron-sulfur (Fe-S) clusters play irreplaceable roles in many metabolic and regulatory processes. They are constructed and distributed to Fe-S proteins by dedicated protein networks. Using bioinformatics, phylogeny, large-scale microbiology and biochemistry approaches, researchers at IRIG have systematically studied the elements that very often render Fe-S proteins inactive outside their native host species.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.