BRCA2 is one of the susceptibility genes for breast and ovarian cancers. To date, this susceptibility has been attributed primarily to the function in DNA repair of the protein encoded by the BRCA2 gene. But what if another BRCA2 function was responsible, or co-responsible, for this pathophysiological mechanism?
In partnership with the Institut Curie, researchers from the CEA-Joliot (I2BC) have shown that three mutations found in patients are responsible for abnormalities during cell division and have dissected these mechanisms.
| Frédéric Joliot Institute for Life Sciences - CEA | I2BC@Saclay
| Curie Institute
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