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Institut de la Direction de la Recherche Fondamentale (DRF) du CEA.
10 Unités Mixtes de Recherche (UMR)
Agenda
Soutenance HDR
Vendredi 19 juin à 10h00 Bât Nanobio au DCM, 301 rue de la Chimie, Campus UGA, SMH
Microorganisms play a crucial role in biotechnologies, enabling the transformation of matter into high-value gases and biomass. At a time when the climate emergency demands a rethinking of our energy models, my work is part of a responsible research approach, aiming to reconcile scientific excellence, environmental sustainability, and economic viability. Over the past twelve years, I have dedicated my career to understanding the molecular mechanisms of the Fur and SUF systems (Fe-S cluster biogenesis, bacterial virulence) and to studying nickel insertion into CO dehydrogenase, using integrated structural approaches (SAXS, MALLS, crystallography). Since 2021, I have refocused my research on energy biotechnologies. After a brief overview of my scientific journey, I will detail my projects on developing solutions for BioH₂ production and CO₂ valorization, particularly through the "Bioraffinery" project (combining photofermentation and methanogenesis), inspired by my participation in the 2022 EIC Horizon Prize. I have optimized photobioreactors (PBRs), improving their light efficiency and achieving up to 5 mol H₂/mol of substrate from PLA waste. Today, I am working on optimizing microbial strains and culture conditions, as well as integrating circular processes for the joint production of BioH₂/BioCH₄. In collaboration with Génoscope, CEA Tech, and industrial partners, I have developed advanced biorafineries to convert by-products into biofuels. My work, at the interface of biophysics, enzymology, and engineering, is part of a decarbonized bioeconomy approach.
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Acteur majeur de la recherche, du développement et de l'innovation, le CEA intervient dans quatre grands domaines : énergies bas carbone, défense et sécurité, technologies pour l’information et technologies pour la santé.