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Highlight | Structural biology | Virus
Researchers at IRIG [collaboration] present a candidate vaccine based on lipid vesicles coated with SARS-CoV-2 glycoprotein, which resemble virus-like particles. After stabilization of glycoprotein S by formaldehyde cross-linking, precilical studies induce high antibody titers with potent neutralizing activity. A third immunization increases antibody titers directed against sequences less prone to mutations and shows complete protection by sterilizing immunity.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.