Fundamental Research Division
The DRF at the CEA assemble approximately 6,000 scientists since January 2016.
Plateforms, equipments and expertise
At the DSV, chemistry is frequently used to develop tools for basic research in biology, diagnostic innovation, industrial biotechnology and green chemistry.
Chemists at the DSV are able to design tools for research in health and energy. Closely linked to biology since the creation of the CEA, the cutting edge radiochemistry developed by its teams is used to design new labeling methods (i.e. for nanotoxicology) and new radiotracers for imaging. Enzymatic chemistry is harnessed in the search for biocatalysts or bio-inspired catalysts for industry. This includes uses in hydrogen production, or the conversion of fine chemical processes by biocatalysis.
The plateform for radiolabeling and radioimaging (at the CEA-IBITECS in Saclay) gathers equipment for radiolabeling molecules and nanoparticles, analyzing radioactive substances, and radioimaging. With its highly specialized skills in radiolabeling, nanotechnology, organic chemistry catalysis, and in vivo beta-ray imaging, the platform provides the knowledge and tools to conduct strategic projects in nanotechnology and drug delivery, as well as advanced technological developments. Supervisors: David BUISSON, Vincent DIVE, Bernard ROUSSEAU, Frédéric TARAN
The chemistry and radiochemistr group within the SHFJ (at the CEA-I2BM in Orsay) specializes in handling fluorine-18 and carbon-11, two radioactive isotopes useful to PET. The group develops new methods for radiolabeling various chemical functions. In particular, this includes designing, developing and preparing new radiotracers for PET scan exams. Supervisor: Frédéric DOLLÉ
The plateform for screening bioconversion activities (at the CEA-IG in Évry) draws on the diverse and continuously enriched collection of bacterial strains from the Genoscope, and on metagenomes in order to discover new enzymatic activities. Their goal is to provide industry with an enzyme-based green chemistry. Other teams are working on bio-inspired chemistry, to offer compounds capable of executing chemical reactions of interest to industry. This is the case of the Chemistry and biology of metals laboratory (CEA-IRTSV) who is developing new metalloenzyme-inspired catalysts.Supervisor: Véronique DE BERARDINIS
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.