Fundamental Research Division
The DRF at the CEA assemble approximately 6,000 scientists since January 2016.
Cellular mechanisms | Cognition | Molecular mechanisms
Researchers at the DSV are expanding the fundamental
knowledge of cellular architecture, organization, regulation, and their
interactions with the exterior environment. They also explore the
biochemical reactions regulating cell functions (e.g. energy production,
manufacture and transport of molecules, damage repair, and waste
elimination). All of this information helps to understand how certain
physiological processes shift from normal to pathological, in addition
to identifying novel therapeutic, diagnostic or methodological leads
This research forms the basis of the CEA’s
innovation in the fields of radiation biology, therapy and diagnosis.
The focus is on three areas:
Researchers at the DSV implement a multi-scale approach to study living organisms, using specific skills at their disposal:
Researchers at the CEA-Irig have succeeded in combining the dynamics of microtubules and actin filaments in a cell-sized compartment, allowing them to position the “microtubule-organizing center”.
Blursday, the first database dedicated to the alteration of the perception of time during the confinement imposed by the COVID-19 pandemic, has been made available to the scientific community by a consortium led by a researcher from the CEA-Joliot. This large-scale participatory study reveals that the feeling of isolation may have induced the perception of slowed time.
Researchers at the CEA-Joliot (NeuroSpin) have succeeded in systematically decoding the cognitive activity associated with various brain activation patterns as recorded by functional MRI. This feat was achieved using neural networks trained on the largest public brain imaging database.
Using almost fully automated processes, researchers at Irig have designed a three-dimensional microenvironment in which cells form a tissue resembling a mini-tumor. Their work opens new perspectives for personalized medicine.
Researchers at the Irig, in collaboration with the CEA-Leti, have developed a microfluidic chip that can measure insulin secretion from a single pancreatic islet. The same technology can be adapted to other biological tissues and secretomes.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.