Fundamental Research Division
The DRF at the CEA assemble approximately 6,000 scientists since January 2016.
In support of its historical activities in the nuclear sector, the CEA has developed expertise in radiobiology and nuclear toxicology. Today this allows the DSV to study the impact of nuclear activities on humans and the environment at the highest level. Similarly, the DSV has implemented for the past decade targeted actions in toxicology to accompany energy applications of nanomaterials (nanotoxicology).
Biotechnologies now have the scientific maturity to propose high-potential devices to respond to the challenges of low-carbon energies and energy-efficient industrial processes. They rely on bioenergetic control mechanisms, and more generally on the mechanisms of biological oxidation-reduction, as well as exploration of the diversity of metabolic pathways of microorganisms.
Imaging, structural biology, large-scale biology, high-throughput screening, and preclinical models are all skills and tools of the DSV for use in the multi-scale study (i.e. molecule, cell, organ, and organism) of normal and pathological biological phenomena. Teams from the DSV are accordingly devoted to working on cancer and infectious, neurodegenerative, or genetic diseases.
The DSV benefits from its fundamental research and skills (chemistry, isotopic labeling, imaging, etc.) to propose innovative approaches in the areas of diagnosis, therapy and prophylaxis. These innovations must contribute to the development of personalized medicine, by allowing physicians to anticipate managing diseases, to avoid ineffective treatments for some patients, and to have more easily tolerated therapies at their disposal.
The interface between biology and technology is a reservoir of innovation that the DSV, by its multidisciplinary culture, has exploited since its creation. At the DSV, computer scientists, chemists, physicists and biologists develop new methods for exploring life. This is a question of enhancing the opportunities offered by research instruments, in order to make this exploration increasingly efficient.This positioning within methodological, procedural, instrumental and software innovation is a specific signature of the DSV, nationally recognized by the award of a mission to lead several major facilities, from the “Investissements d’Avenir” Program.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.