Fundamental Research Division
The DRF at the CEA assemble approximately 6,000 scientists since January 2016.
Drawing upon the 3D reconstruction of the cellular architecture of several phytoplankton families, researchers at the CEA-Irig have demonstrated that the physiological responses of these eukaryotes are associated with certain characteristics of their energy-producing organelles. This work thus provides new perspectives for the production of algal biomass, upstream of biotechnology applications.
Coupled to a novel multi-pore optic inspired by the vision of some crustaceans, the X-ray camera to be used in the MXT telescope of the Franco-Chinese satellite SVOM was designed and assembled by the Irfu and recently delivered to the Cnes. SVOM is scheduled for launch in late 2022.
Using the UK Biobank cohort, researchers at the Joliot-NeuroSpin and the Jacob-CNRGH explored genome-wide associations between groups of linked genes (haplotypes) and the opening of brain sulci, an indicator of brain aging.
Based in particular on multiscale morphological analyses, researchers at the CEA-Irig have developed a new generation of hybrid proton exchange membranes for fuel cells with promising performance and durability.
Researchers at the Irig have developed an application to help biologists prepare their large-scale experiments using randomly distributed well plates, without requiring any programming skills.
Different greenhouse gases do not have the same levels of persistence in the atmosphere. The calculation of their CO2 equivalent emissions therefore depends on the time periods in question. According to a collaboration led by the LSCE (CEA-CNRS-UVSQ), adjusting these durations will make it possible to better identify the most economically advantageous policies for reducing warming.
Researchers at the CEA-Jacob have reported a new optimized strategy to treat β-thalassemia that uses a lentiviral gene therapy vector.
Researchers at the CEA-Jacob have shown that activation of the PPAR-γ receptor is a relevant therapeutic target for the management of myelofibrosis. This work signals that agonists of PPAR-γ could be introduced into clinical practice.
Thanks to an innovative approach developed by researchers at the Irig, the CEA-Leti and their partners, the identification of phages effective against antibiotic-resistant bacteria has been accelerated and the number of false negatives reduced. This work opens up the possibility of using phage therapy in hospitals!
Scientists from the Institute of Structural Biology (Irig) and their partners have confirmed that the COVID-19 virus can use immune cells to increase its transmission to other cells. They also show that it is possible to inhibit this new mode of transmission of the virus through the use of glycomimetics, i.e. molecules that can mimic the surface “sugars” of the virus.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.