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DRCM Publications

Publié le 6 janvier 2026
  
A coordinated haptic mechanism ensures efficient DNA sampling by the 8-oxoguanine glycosylase OGG1

Martinez M, D'Augustin O, Chousianiti DM, Gaudon V, Coste F, Gil Quevedo A, Bigot N, Chapuis C, Di Guilmi AM, Hubert JF, Castaing B, Campalans A, Huet S.

2026
Heritable ER stress impairs mitochondrial metabolism and maintenance of hematopoietic stem cells after low-dose irradiation.

Moreno SG, Ferri F, Lewandowski D, Barroca V, Devanand S, Dechamps N, Romeo PH, Gault N.

2026
Mitotic dynamics of the nuclear lamina in the backstage of chromosome separation

Picotto J, Bertrand P, Pennarun G.

2025
A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes

Dewailly M, Fauconnet Y, Ducrot C, Soulet AL, Campo N, Guerois R, Radicella JP*, Polard P, Andreani J*, Johnston CHG* (*co-corresponding authors​)

2025
In Vitro Lymphoid Differentiation of Human Hematopoietic Progenitor Cells from Co-cultures in Hypoxia

Pflumio F, Haddad R.

2025
No specific impact of ultra-high dose rates on radiation-induced chromosome rearrangements

Pobiega S, Drevet Mulard E, Ménard V, Ristic Y, Trompier F, Gruel G, Marcand S.

2025
Light-triggered quenching of the 19F-MRI signal from micelle-encapsulated PERFECTA.

​Leterrier C, Pinna G, Vandamme M, Glatigny M, Selingue E, Geffroy F, Mériaux S, Gravel E, Doris E.

2025
G-quadruplex ligand RHPS4 compromises cellular radioresistance by inhibiting the mitochondrial adaptive response induced by ionizing irradiation

​Tricot S, Siberchicot C, Bontemps I, Desmaze C, Kratassiouk G, Vandamme M, Pinna G, Nemazanyy I, Radicella JP, Lenaers G, Renaudin X, Lebeau J, Campalans A

2025
Is the TEX11-.652del237bp Exonic In-Frame Deletion Variant Associated with Azoospermia? The Results of an In Vitro and In Silico Study.

Le Beulze M, Poidatz D, Francisco M, Madec FX, Benetti PH, Livera G, Vialard F.

2025
An evolutionarily conserved role for separase in the regulation of nuclear lamins.

Cipressa F, Pennarun G, Bosso G, Rosignoli S, Tullo L, Schiralli N, Di Dio C, Borghi C, Paiardini A, Esposito G, Goldberg ML,  Bertrand P, Cenci G​.

2025
The Uptake of Metallic Nanoparticles in Breast Cancer Cell Lines is Modulated by the Hyaluronan-CD44 Axis.

Hullo M, Mathé C, Fonknechten N, Lacrouts C, Piton G, Noireaux J, Chevillard S, Campalans A, Bourneuf E.

2025
Restriction of Ku translocation protects telomere ends

Mattarocci S, Baconnais S, Roisné-Hamelin F, Pobiega S, Alibert O, Morin V, Deshayes A, Veaute X, Ropars V, Chevreuil M, Mehringer J, Busso D, Mazon G, Fernandez Varela P, Le Cam É, Charbonnier JB, Cuniasse P, Marcand S.

2025
Telomeres stall DNA loop extrusion by condensin

Analikwu BT, Deshayes A, van der Torre J, Guérin TM, Katan AJ, Béneut C, Barth R, Phipps J, Scolari V, Veaute X, Busso D, Dubrana K, Mattarocci S, Dekker C, Marcand S.

2025
A large C-terminal Rad52 segment acts as a chaperone to Form and Stabilize Rad51 Filaments.

​Ma E, Lakhal F, Litsardaki E, Ruault M, Audin M, Levrier N, Navarro E, Garnier M, Maloisel L, Depagne J, Brocas C, Thureau A, Busso D, Veaute X, Guerois R, Taddei A*, Ochsenbein F*, Coïc E*. [*co-last / co-corresponding]

2025
Micelles based on a poly(2-oxazoline) triblock copolymer containing a pure stereoisomer E or Z-tetraphenylethylene core for theranostic applications.

Hoang S, Pinna G, Vandamme M, Allain M, Passirani C, Saulniera P, Krupka O.

2025
The LRP4/YAP axis drives the radiation-tolerant persister (RTP) cell state in breast cancer.

Forissier V, Wicinski J, Castagné M, Pinna G, Lin S, Grandon A, Bonnet C, Macario M, Castellano R, Valdenaire S, Darréon J, Tallet A, Ginestier C, Charafe-Jauffret E.

2025
The DNA damage tolerance factor Rad5 and telomere replication

Mattarocci S.

2025
Modulation of OGG1 enzymatic activities by small molecules, promising tools and current challenges.

Renaudin X, Campalans A.

2025
Orchestration of human multi-lineage hematopoietic cell development by humanized in vivo bone marrow models

​Renou L, Sun W, Friedrich C, Galant K, Conrad C, Consalus A, Plantier E, Schallmoser K, Krisch L, Barroca V, Devanand S, Dechamps N, Reinisch A, Martinovic J, Magnani A, Faivre L, Lewandowski D, Calvo J, Perie L, Kosmider O, Pflumio F

2025
DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria.

​Dalia, T.N., Machouri, M., Lacrouts, C., Fauconnet, Y., Guerois, R., Andreani, J.*, Radicella, J.P.*, Dalia, A.B.* (* co-corresponding authors)

2025
Progressive chromatin rewiring by ETO2::GLIS2 revealed in a genome-edited human iPSC model of pediatric leukemia initiation

​Boudia F, Baille M, Babin L, Aid Z, Robert E, Rivière J, Galant K, Alonso-Pérez V, Anselmi L, Arkoun B, Abermil N, Marzac C, Bertuccio SN, de Prémesnil A, Lopez CK, Eeckhoutte A, Naimo A, Leite B, Catelain C, Metereau C, Gonin P, Gaspar N, Schwaller J, Bernard OA, Raslova H, Gaudry M, Marchais A, Lapillonne H, Petit A, Pflumio F, Arcangeli ML, Brunet E, Mercher T

2025
Inhibition of the STAT3/Fanconi anemia axis is synthetic lethal with PARP inhibition in breast cancer.

Rouault CD, Bansard L, Martínez-Balsalobre E, Bonnet C, Wicinski J, Lin S, Colombeau L, Debieu S, Pinna G, Vandamme M, Machu M, Rosnet O, Chevrier V, Popovici C, Sobol H, Castellano R, Pasquier E, Guasch G, Rodriguez R, Pannequin J, Pascussi JM, Lachaud C, Charafe-Jauffret E, Ginestier C.

2025
Long Noncoding VIM-AS1: Biomarker of Breast Fibrosis Susceptibility After Radiation Therapy and Promoter of Transforming Growth Factor Beta1-Driven Fibrosis.

Vinasco-Sandoval T, Moratille S, Crechet F, Mesloub Y, Montanari J, Auvré F, Deleuze JF, Foray N, Fortunel NO*, Martin MT* [*co-last / co-corresponding]. 

2025
High CD44 expression and enhanced E-selectin binding identified as biomarkers of chemoresistant leukemic cells in human T-ALL

​Calvo J, Naguibneva I, Kypraios A, Gilain F, Uzan B, Gaillard B, Bellenger L, Renou L, Antoniewski C, Lapillonne H, Petit A, Ballerini P, Mancini SJ, Marchand T, Peyron JF, Pflumio F

2025
Replication Stress Is an Actionable Genetic Vulnerability in Desmoplastic Small Round Cell Tumors.

Kawai-Kawachi A, Lenormand MM, Astier C, Herbel N, Cutrona MB, Ngo C, Garrido M, Eychenne T, Dorvault N, Bordelet L, Song F, Bouyakoub R, Loktev A, Romo-Morales A, Henon C, Colmet-Daage L, Vibert J, Drac M, Brough R, Schwob E, Martella O, Pinna G, Shipley JM, Mittnacht S, Zimmermann A, Gulati A, Mir O, Le Cesne A, Faron M, Honoré C, Lord CJ, Chabanon RM, Postel-Vinay S.

2025
The AXL inhibitor bemcentinib overcomes microenvironment-mediated resistance to pioglitazone in acute myeloid leukemia

​Zhu J, Guérineau H, Lefebvre-Fortané AM, Largeaud L, Lambert J, Rousselot P, Boudouin M, Calvo J, Prost S, Clauser S, Bardet V​

2025
Developmental interplay between transcriptional alterations and a targetable cytokine signaling dependency in pediatric ETO2::GLIS2 leukemia

​Alonso-Pérez V, Galant K, Boudia F, Robert E, Aid Z, Renou L, Barroca V, Devanand S, Babin L, Rouiller-Fabre V, Moison D, Busso D, Piton G, Metereau C, Abermil N, Ballerini P, Hirsch P, Haddad R, Martinovic J, Petit A, Lapillonne H, Brunet E, Mercher T, Pflumio F

2024
Multiple Mechanisms of Action of Sulfodyne®, a Natural Antioxidant, against Pathogenic Effects of SARS-CoV-2 Infection

​Romeo PH, Conquet L, Messiaen S, Pascal Q, Moreno SG, Bravard A, Bernardino-Sgherri J, Dereuddre-Bosquet N, Montagutelli X, Le Grand R, Petit V, Ferri F​

2024
T-cell acute lymphoblastic leukemia progression is supported by inflammatory molecules including hepatocyte growth factor

​Le Maout C, Fahy L, Renou L, Devanand C, Duwat C, Barroca V, Le Gall M, Ballerini P, Petit A, Calvo J, Uzan B, Pflumio F, Petit V

2024
The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300-dependent stemness program

​Fagnan A, Aid Z, Baille M, Drakul A, Robert E, Lopez CK, Thirant C, Lecluse Y, Rivière J, Ignacimouttou C, Salmoiraghi S, Anguita E, Naimo A, Marzac C, Pflumio F, Malinge S, Wichmann C, Huang Y, Lobry C, Chaumeil J, Soler E, Bourquin JP, Nerlov C, Bernard OA, Schwaller J, Mercher T

2024
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