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Publications de l'IRCM

Publié le 2 juillet 2018
  
Rad52 Oligomeric N-Terminal Domain Stabilizes Rad51 Nucleoprotein Filaments and Contributes to Their Protection against Srs2
Ma, E., Maloisel, L., Le Falher, L., Guérois, R., Coïc, E
2021
The homologous recombination complex of the Rad51 paralogs Rad55-Rad57 avoids translesion DNA polymerase recruitment and counterbalances mutagenesis induced by UV radiation
Maloisel, L., Ma, E., Coïc, E. 
2021
The meiosis-specific MEIOB–SPATA22 complex cooperates with RPA to form a compacted mixed MEIOB/SPATA22/RPA/ssDNA complex
Jonathan Ribeiro, Pauline Dupaigne, Cynthia Petrillo, Cécile Ducrot, Clotilde Duquenne, Xavier Veaute, Carole Saintomé, Didier Busso, Raphaël Guerois, Emmanuelle Martini, Gabriel Livera
2021
Mechanism of MRX inhibition by Rif2 at telomeres
Florian Roisné-Hamelin, Sabrina Pobiega, Kévin Jézéquel, Simona Miron, Jordane Dépagne, Xavier Veaute, Didier Busso, Marie-Hélène Le Du, Isabelle Callebaut, Jean-Baptiste Charbonnier, Philippe Cuniasse, Sophie Zinn-Justin & Stéphane Marcand
2021
Tumor resistance to radiotherapy is triggered by an ATM/TAK1-dependent-increased expression of the cellular prion protein
Jacqueline Bernardino-Sgherri, Capucine Siberchicot, Frédéric Auvré, Didier Busso, Clémentine Brocas, Ghazi El Masri, Anna Lioutsko, Federica Ferri, J Pablo Radicella, Paul-Henri Romeo, Anne Bravard
2021
Experimental and Preclinical Tools to Explore the Main Neurological Impacts of Brain Irradiation: Current Insights and Perspectives
Mouton L, Ribeiro R, Mouthon MA, Boumezbeur F, Le Bihan D, Ricard D, Boussin F, Verrelle P
2021
Hypoxia favors chemoresistance in T-ALL through a HIF1-mediated mTORC1 inhibition loop
L Fahy, J Calvo, S Chabi, L Renou, C Le Maout, S Poglio, T Leblanc, A Petit, A Baruchel, P Ballerini, I Naguibneva, R Haddad, ML Arcangeli, F Mazurier, F Pflumio* and B Uzan
2021
A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization
Forey R., Barthe A., Tittel-Elmer M., Wery M, Barrault M. B., Ducrot C., Seeber A, Krietenstein N., Szachnowski U., Skryzpczak M., Rowicka M., Ginalski K., Cobb J., Rando O., Soutourina J., Dubrana  K., Gasser S., Morillon A., Pasero P., Lengronne A. and Poli J
2021
A peptide of a type I toxin-antitoxin system induces Helicobacter pylori morphological transformation from spiral shape to coccoids
Lamya El Mortaji, Alejandro Tejada-Arranz, Aline Rifflet, Ivo G. Boneca, Gerard Pehau-Arnaudet, J. Pablo Radicella, Stephanie Marsin and Hilde De Reuse
2020
Cognitive effects of low dose of ionizing radiation - Lessons learned and research gaps from epidemiological and biological studies
Pasqual E, Boussin F, Bazyka D, Nordenskjold A, Yamada M, Ozasa K, Pazzaglia S, Roy L, Thierry-Chef I, de Vathaire F, Benotmane MA, Cardis E
2020
Stimulates Adult Neurogenesis in the Mouse Ventricular-Subventricular Zone after Injury
Mouthon MA, Morizur L, Dutour L, Pineau D, Kortulewski T, Boussin FD.
2020
A genetic variant controls interferon-? gene expression in human myeloid cells by preventing C/EBP-? binding on a conserved enhancer
Assouvie, A., Rotival, M., Hamroune, J., Busso, D., Romeo, P.-H., Quintana-Murci, L. and Rousselet, G.
2020
Exposure of Human Skin Organoids to Low Genotoxic Stress Can Promote Epithelial-to-Mesenchymal Transition in Regenerating Keratinocyte Precursor Cells.
Cavallero S, Neves Granito R, Stockholm D, Azzolin P, Martin MT, Fortunel NO.
2020
Fibroblasts from the Human Skin Dermo-Hypodermal Junction are Distinct from Dermal Papillary and Reticular Fibroblasts and from Mesenchymal Stem Cells and Exhibit a Specific Molecular Profile Related to Extracellular Matrix Organization and Modeling.
Haydont V, Neiveyans V, Perez P, Busson E, Lataillade J, Asselineau D, Fortunel NO.
2020
Impairment of base excision repair in dermal fibroblasts isolated from Nevoid Basal Cell Carcinoma patients.
Charazac A, Fayyad N, Beal D, Bourgoin-Voillard S, Seve M, Sauvaigo S, Lamartine J, Soularue P, Moratille S, Martin MT, Ravanat JL, Douki T and Rachidi W.
2020
The HIF1a/JMY pathway promotes glioblastoma stem-like cells invasiveness after irradiation.
Gauthier, L.R., Saati, M., Bensalah-Pigeon, H., Ben M’Barek, K., Gitton-Quent, O., Bertrand, R., Busso, D., Mouthon, M.A., Collura, A., Junier, M.-P., Chneiweiss, H., Pineda, J.R. and Boussin, F.D
2020
When stemness genes meet skin graft bioengineering: focus on KLF4
Fortunel NO et Martin MT.
2020
When the Search for Stemness Genes Meets the Skin Substitute Bioengineering Field: KLF4 Transcription Factor under the Light.
Fortunel NO and Martin MT.
2020
NFATC2 modulates radiation toxicity in dermal fibroblasts from patients with severe side-effects of radiotherapy.
Dulong J, Kouakou C, Mesloub Y, Rorteau J, Moratille S, Chevalier F, Vinasco Sandoval T, Martin MT and Lamartine J.
2020
Desperately seeking a home marrow niche for T-cell acute lymphoblastic leukaemia.
Calvo J, Fahy L, Uzan B, Pflumio F.
2019
Combined G-CSF and Plerixafor enhance hematopoietic recovery of CD34+ cells from poor mobilizer patients in NSG mice.
Arcangeli ML, Brault P, Bourhis JH, Kuhnowski F, Henry E, Barroca V et al.
2020
Lost in the Crowd: How Does Human 8-Oxoguanine DNA Glycosylase 1 (OGG1) Find 8-Oxoguanine in the Genome?
Ostiane D'Augustin, Sébastien Huet, Anna Campalans, Juan Pablo Radicella 
2020
Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia.
Zhou Y, Han C, Wang E, Lorch AH, Serafin V, Cho B-K et al.
2020
Ultra-high dose rate FLASH and conventional dose rate irradiation differentially affect human acute lymphoblastic leukemia and normal hematopoiesis.
Chabi S, Hong Van To T, Leavitt R, PhD4, Poglio S, Gonçalves Jorge P , Jaccard M, PeterssonK, Petit B, Roméo, PH, Pflumio,F, Vozenin, MC and Uzan, B
2020
AsiDNA is a radiosensitizer with no added toxicity in medulloblastoma pediatric models
Ferreira S, Foray C, Gatto A, Larcher M, Heinrich S, Lupu M, Mispelter J, Boussin FD, Pouponnot C, Dutreix M
2020
Higher chromosome stability in embryonic neural stem and progenitor cells than in fibroblasts in response to acute or chronic genotoxic stress
Mokrani S, Granotier-Beckers C, Etienne O, Kortulewski T, Grisolia C, de Villartay JP, Boussin FD
2020
Human hematopoietic stem/progenitor cells display reactive oxygen species-dependent long-term hematopoietic defects after exposure to low doses of ionizing radiations
Elia Henry, Inès Souissi-Sahraoui, Margaux Deynoux, Andréas Lefèvre, Vilma Barroca, Anna Campalans, Véronique Ménard, Julien Calvo, Françoise Pflumio, Marie-Laure Arcangeli
2020
MasterPATH: network analysis of functional genomics screening data
Natalia Rubanova, Guillaume Pinna, Jeremie Kropp, Anna Campalans, Juan Pablo Radicella, Anna Polesskaya, Annick Harel-Bellan, Nadya Morozova
2020
CD117 hi expression identifies a human fetal hematopoietic stem cell population with high proliferation and self-renewal potential
Loïc Maillard, Sandra Sanfilippo, Carine Domenech, Nassima Kasmi, Laurence Petit, Sébastien Jacques, Anne-Lise Delezoide, Fabien Guimiot, Soria Eladak, Delphine Moison, Nour Nicolas, Virginie Rouiller-Fabre, Stéphanie Pozzi-Godin, Benoit Mennesson, Marie-Laure Brival, Franck Letourneur, Thierry Jaffredo, Christine Chomienne, Michèle Souyri
2020
Different exposure windows to low doses of genistein and/or vinclozolin result in contrasted disorders of testis function and gene expression of exposed rats and their unexposed progeny
Florence Eustache, Badria Bennani Smires, Delphine Moison, Raymond Bergès, Marie-Chantal Canivenc-Lavier, Daniel Vaiman, Jacques Auger
2020
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