 | | A coordinated haptic mechanism ensures efficient DNA sampling by the 8-oxoguanine glycosylase OGG1 | Martinez M, D'Augustin O, Chousianiti DM, Gaudon V, Coste F, Gil Quevedo A, Bigot N, Chapuis C, Di Guilmi AM, Hubert JF, Castaing B, Campalans A, Huet S.
| | 2026 |  |  | | Mitotic dynamics of the nuclear lamina in the backstage of chromosome separation | Picotto J, Bertrand P, Pennarun G.
| | 2025 |  |  | | A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes | Dewailly M, Fauconnet Y, Ducrot C, Soulet AL, Campo N, Guerois R, Radicella JP*, Polard P, Andreani J*, Johnston CHG* (*co-corresponding authors)
| | 2025 |  |  | | In Vitro Lymphoid Differentiation of Human Hematopoietic Progenitor Cells from Co-cultures in Hypoxia | | | 2025 |  |  | | No specific impact of ultra-high dose rates on radiation-induced chromosome rearrangements | Pobiega S, Drevet Mulard E, Ménard V, Ristic Y, Trompier F, Gruel G, Marcand S.
| | 2025 |  |  | | G-quadruplex ligand RHPS4 compromises cellular radioresistance by inhibiting the mitochondrial adaptive response induced by ionizing irradiation | Tricot S, Siberchicot C, Bontemps I, Desmaze C, Kratassiouk G, Vandamme M, Pinna G, Nemazanyy I, Radicella JP, Lenaers G, Renaudin X, Lebeau J, Campalans A
| | 2025 |  |  | | Is the TEX11-.652del237bp Exonic In-Frame Deletion Variant Associated with Azoospermia? The Results of an In Vitro and In Silico Study. | Le Beulze M, Poidatz D, Francisco M, Madec FX, Benetti PH, Livera G, Vialard F.
| | 2025 |  |  | | An evolutionarily conserved role for separase in the regulation of nuclear lamins. | Cipressa F, Pennarun G, Bosso G, Rosignoli S, Tullo L, Schiralli N, Di Dio C, Borghi C, Paiardini A, Esposito G, Goldberg ML, Bertrand P, Cenci G.
| | 2025 |  |  | | The Uptake of Metallic Nanoparticles in Breast Cancer Cell Lines is Modulated by the Hyaluronan-CD44 Axis. | Hullo M, Mathé C, Fonknechten N, Lacrouts C, Piton G, Noireaux J, Chevillard S, Campalans A, Bourneuf E.
| | 2025 |  |  | | Restriction of Ku translocation protects telomere ends | Mattarocci S, Baconnais S, Roisné-Hamelin F, Pobiega S, Alibert O, Morin V, Deshayes A, Veaute X, Ropars V, Chevreuil M, Mehringer J, Busso D, Mazon G, Fernandez Varela P, Le Cam É, Charbonnier JB, Cuniasse P, Marcand S.
| | 2025 |  |  | | Telomeres stall DNA loop extrusion by condensin | Analikwu BT, Deshayes A, van der Torre J, Guérin TM, Katan AJ, Béneut C, Barth R, Phipps J, Scolari V, Veaute X, Busso D, Dubrana K, Mattarocci S, Dekker C, Marcand S.
| | 2025 |  |  | | The LRP4/YAP axis drives the radiation-tolerant persister (RTP) cell state in breast cancer. | Forissier V, Wicinski J, Castagné M, Pinna G, Lin S, Grandon A, Bonnet
C, Macario M, Castellano R, Valdenaire S, Darréon J, Tallet A, Ginestier C,
Charafe-Jauffret E.
| | 2025 |  |  | | The DNA damage tolerance factor Rad5 and telomere replication | | | 2025 |  |  | | Modulation of OGG1 enzymatic activities by small molecules, promising tools and current challenges. | Renaudin X, Campalans A.
| | 2025 |  |  | | Orchestration of human multi-lineage hematopoietic cell development by humanized in vivo bone marrow models | Renou L, Sun W, Friedrich C, Galant K, Conrad C, Consalus A, Plantier E, Schallmoser K, Krisch L, Barroca V, Devanand S, Dechamps N, Reinisch A, Martinovic J, Magnani A, Faivre L, Lewandowski D, Calvo J, Perie L, Kosmider O, Pflumio F
| | 2025 |  |  | | DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria. | Dalia, T.N., Machouri, M., Lacrouts, C., Fauconnet, Y., Guerois, R., Andreani, J.*, Radicella, J.P.*, Dalia, A.B.* (* co-corresponding authors)
| | 2025 |  |  | | Progressive chromatin rewiring by ETO2::GLIS2 revealed in a genome-edited human iPSC model of pediatric leukemia initiation | Boudia F, Baille M, Babin L, Aid Z, Robert E, Rivière J, Galant K, Alonso-Pérez V, Anselmi L, Arkoun B, Abermil N, Marzac C, Bertuccio SN, de Prémesnil A, Lopez CK, Eeckhoutte A, Naimo A, Leite B, Catelain C, Metereau C, Gonin P, Gaspar N, Schwaller J, Bernard OA, Raslova H, Gaudry M, Marchais A, Lapillonne H, Petit A, Pflumio F, Arcangeli ML, Brunet E, Mercher T
| | 2025 |  |  | | Inhibition of the STAT3/Fanconi anemia axis is synthetic lethal with PARP inhibition in breast cancer. | Rouault CD, Bansard L, Martínez-Balsalobre E, Bonnet C, Wicinski J, Lin
S, Colombeau L, Debieu S, Pinna G, Vandamme M, Machu M, Rosnet O, Chevrier V,
Popovici C, Sobol H, Castellano R, Pasquier E, Guasch G, Rodriguez R, Pannequin
J, Pascussi JM, Lachaud C, Charafe-Jauffret E, Ginestier C.
| | 2025 |  |  | | High CD44 expression and enhanced E-selectin binding identified as biomarkers of chemoresistant leukemic cells in human T-ALL | Calvo J, Naguibneva I, Kypraios A, Gilain F, Uzan B, Gaillard B, Bellenger L, Renou L, Antoniewski C, Lapillonne H, Petit A, Ballerini P, Mancini SJ, Marchand T, Peyron JF, Pflumio F
| | 2025 |  |  | | Replication Stress Is an Actionable Genetic Vulnerability in Desmoplastic Small Round Cell Tumors. | Kawai-Kawachi A, Lenormand MM, Astier C, Herbel N, Cutrona MB, Ngo C,
Garrido M, Eychenne T, Dorvault N, Bordelet L, Song F, Bouyakoub R, Loktev A,
Romo-Morales A, Henon C, Colmet-Daage L, Vibert J, Drac M, Brough R, Schwob E,
Martella O, Pinna G, Shipley JM, Mittnacht S, Zimmermann A, Gulati A, Mir O, Le
Cesne A, Faron M, Honoré C, Lord CJ, Chabanon RM, Postel-Vinay S.
| | 2025 |  |  | | The AXL inhibitor bemcentinib overcomes microenvironment-mediated resistance to pioglitazone in acute myeloid leukemia | Zhu J, Guérineau H, Lefebvre-Fortané AM, Largeaud L, Lambert J, Rousselot P, Boudouin M, Calvo J, Prost S, Clauser S, Bardet V
| | 2025 |  |  | | Developmental interplay between transcriptional alterations and a targetable cytokine signaling dependency in pediatric ETO2::GLIS2 leukemia | Alonso-Pérez V, Galant K, Boudia F, Robert E, Aid Z, Renou L, Barroca V, Devanand S, Babin L, Rouiller-Fabre V, Moison D, Busso D, Piton G, Metereau C, Abermil N, Ballerini P, Hirsch P, Haddad R, Martinovic J, Petit A, Lapillonne H, Brunet E, Mercher T, Pflumio F
| | 2024 |  |  | | Multiple Mechanisms of Action of Sulfodyne®, a Natural Antioxidant, against Pathogenic Effects of SARS-CoV-2 Infection | Romeo PH, Conquet L, Messiaen S, Pascal Q, Moreno SG, Bravard A, Bernardino-Sgherri J, Dereuddre-Bosquet N, Montagutelli X, Le Grand R, Petit V, Ferri F
| | 2024 |  |  | | T-cell acute lymphoblastic leukemia progression is supported by inflammatory molecules including hepatocyte growth factor | Le Maout C, Fahy L, Renou L, Devanand C, Duwat C, Barroca V, Le Gall M, Ballerini P, Petit A, Calvo J, Uzan B, Pflumio F, Petit V
| | 2024 |  |  | | The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300-dependent stemness program | Fagnan A, Aid Z, Baille M, Drakul A, Robert E, Lopez CK, Thirant C, Lecluse Y, Rivière J, Ignacimouttou C, Salmoiraghi S, Anguita E, Naimo A, Marzac C, Pflumio F, Malinge S, Wichmann C, Huang Y, Lobry C, Chaumeil J, Soler E, Bourquin JP, Nerlov C, Bernard OA, Schwaller J, Mercher T
| | 2024 |  |  | | CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia | Cardoso BA, Duque M, Gírio A, Fragoso R, Oliveira ML, Allen JR, Martins LR, Correia NC, Silveira AB, Veloso A, Kimura S, Demoen L, Matthijssens F, Jeha S, Cheng C, Pui CH, Grosso AR, Neto JL, De Almeida SF, Van Vlieberghe P, Mullighan CG, Yunes JA, Langenau DM, Pflumio F, Barata JT
| | 2024 |  |  | | Identifying Candidate Gene Drivers Associated with Relapse in Pediatric T-Cell Acute Lymphoblastic Leukemia Using a Gene Co-Expression Network Approach | Kypraios A, Bennour J, Imbert V, David L, Calvo J, Pflumio F, Bonnet R, Couralet M, Magnone V, Lebrigand K, Barbry P, Rohrlich PS, Peyron JF
| | 2024 |  |  | | Targeted nuclear irradiation with a proton microbeam induces oxidative DNA base damage and triggers the recruitment of DNA glycosylases OGG1 and NTH1. | Robeska E, Lalanne K, Vianna F, Sutcu HH, Khobta A, Busso D, Radicella JP, Campalans A*, Baldeyron C*. (* co-corresponding authors)
| | 2024 |  |  | | Deciphering the immune reaction leading to spontaneous melanoma regression: initial role of MHCII+ CD163- macrophages | Blanc F, Bertho N, Piton G, Leplat JJ, Egidy G, Bourneuf E, Vincent-Naulleau S, Prévost-Blondel A.
| | 2023 |  |  | | A R-loop sensing pathway mediates the relocation of transcribed genes to nuclear pore complexes. | Penzo A, Dubarry M, Brocas C, Zheng M, Mangione RM, Rougemaille M, Goncalves C, Lautier O, Libri D, Simon MN, Géli V, Dubrana K, Palancade B. | | 2023 |  |
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