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Publications du SEPIA

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Publié le 4 juillet 2018
Long Term Gene Expression in Human Induced Pluripotent Stem Cells and Cerebral Organoids to Model a Neurodegenerative Disease
Nassor F,  Jarray R,  Maïza A, Papy-Garcia D, Pavoni S, Deslys JP, Yates F
Neuropathology of iatrogenic Creutzfeldt-Jakob disease and immunoassay of French cadaver-sourced growth hormone batches suggest possible transmission of tauopathy and long incubation periods for the transmission of Abeta pathology.
Duyckaerts C, Sazdovitch V, Ando K, Seilhean D, Privat N, Yilmaz Z, Peckeu L, Amar E, Comoy E, Maceski A, Lehmann S, Brion JP, Brandel JP, Haïk S
Small-molecule induction of Abeta-42 peptide production in human cerebral organoids to model Alzheimer's disease associated phenotypes
Pavoni S, Jarray R, Nassor F, Guyot AC, Cottin S, Rontard J, Mikol J, Mabondzo A, Deslys JP, Yates F
Unexpected prion phenotypes in experimentally transfused animals: predictive models for humans?
Comoy E, Mikol J, Deslys JP
Differential overexpression of SERPINA3 in human prion diseases.
Vanni S, Moda F, Zattoni M, Bistaffa E, De Cecco E, Rossi M, Giaccone G, Tagliavini F, Haïk S, Deslys JP, Zanusso G, Ironside JW, Ferrer I, Kovacs GG, Legname G
Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer's disease brains
Dudeffant C, Vandesquille M, Herbert K, Garin CM, Alves S, Blanchard V, Comoy EE, Petit,F, Dhenain M
Experimental transfusion of variant CJD-infected blood reveals previously uncharacterised prion disorder in mice and macaque
Comoy EE, Mikol J, Jaffre N, Lebon V, Levavasseur E, Streichenberger N, Sumian C, Perret-Liaudet A, Eloit M, Andreoletti O, Haik, S, Hantraye, P, Deslys, JP
Induced pluripotent stem cell generation from a man carrying a complex chromosomal rearrangement as a genetic model for infertility studies
Mouka A, Izard V, Tachdjian G, Brisset S, Yates F, Mayeur A, Drevillon L, Jarray R, Leboulch P, Maouche-Chretien L, Tosca L
Detection and partial discrimination of atypical and classical bovine spongiform encephalopathies in cattle and primates using real-time quaking-induced conversion assay
Levavasseur E, Biacabe AG, Comoy E, Culeux A, Grznarova K, Privat N, Simoneau S, Flan B, Sazdovitch V, Seilhean D, Baron T, Haik S
PLoS ONE, 2017
Forced extinction of CD24 stem-like breast cancer marker alone promotes radiation resistance through the control of oxidative stress
Bensimon J, Biard D, Paget V, Goislard M, Morel-Altmeyer S, Konge J, Chevillard S, Lebeau J
Validation of an air-liquid interface toxicological set-up using Cu, Pd, and Ag well-characterized nanostructured aggregates and spheres
Svensson CR, Ameer SS, Ludvigsson L, Ali N, Alhamdow A, Messing ME, Pagels J, Gudmundsson A, Bohgard M, Sanfins E, Karedal M, Broberg K, Rissler J
New insights in the transfusional risk assessment of variant Creutzfeldt-Jakob Disease: Transfusional transmission of vCJD prions in the absence of detectable abnormal prion protein
Comoy EE, Jaffre N, Mikol J, Durand V, Lescoutra-Etchegaray N, Levavasseur E, Streichenberger N, Haik S, Deslys JP
Prion, 2016
Transmission of prions to non human-primates: Implications for human populations
Deslys JP, Comoy EE
Prion, 2016
Non-equivalent binding sites for Abeta1-40 on PrP determine the oligomerisation pathway
Grznarova K, Torrent J, Munoz-Montesino C, Nasica J, Derreumaux P, Beringue V, Deslys JP, Rezaei H
Prion, 2016
A novel approach combining 3D human cell culture and 3D microscopy to assess prion infectivity
Nassor F, Pavoni S, Jarray R, Jouy D, Cottin S, Rontard J, Comoy EE, BIARD DSF, Yates F, Deslys JP
Prion, 2016
Impact of Astroglial Connexins on Modafinil Pharmacological Properties
Duchene A, Perier M, Zhao Y, Liu XH, Thomasson J, Chauveau F, Pierard C, Lagarde D, Picoli C, Jeanson T, Mouthon F, Dauvilliers Y, Giaume C, Lin JS, Charveriat M
Sleep, 2016
Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells
Quinet A, Martins DJ, Vessoni AT, Biard D, Sarasin A, Stary A, Menck CFM
Nucleic Acids Res., 2016
A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation
Gemble S, Buhagiar-Labarchede G, Onclercq-Delic R, Biard D, Lambert S, Amor-Gueret M
J. Cell Sci., 2016
Detection of exosomal prions in blood by immunochemistry techniques
Properzi F, Logozzi M, Abdel-Haq H, Federici C, Lugini L, Azzarito T, Cristofaro I, di Sevo D, Ferroni E, Cardone F, Venditti M, Colone M, Comoy E, Durand V, Fais S, Pocchiari M
Interaction with OGG1 is required for efficient recruitment of XRCC1 to base excision repair and maintenance of genetic stability after exposure to oxidative stress
Campalans A, Moritz E, Kortulewski T, Biard D, Epe B, Radicella JP
Mol. Cell. Biol., 2015
Blood reference materials from macaques infected with variant Creutzfeldt-Jakob disease agent
McDowell KL, Nag N, Franco Z, Bu M, Piccardo P, Cervenak J, Deslys JP, Comoy E, Asher DM, Gregori L
Transfusion, 2015
The prion protein is critical for DNA repair and cell survival after genotoxic stress
Bravard A, Auvre F, Fantini D, Bernardino-Sgherri J, Sissoeff L, Daynac M, Xu Z, Etienne O, Dehen C, Comoy E, Boussin FD, Tell G, Deslys JP, Radicella JP
Nucleic Acids Res., 2015
Creating conditions for the success of the French industrial advanced therapy sector
Lirsac PN, Blin O, Magalon J, Angot P, de Barbeyrac E, Bilbault P, Bourg E, Damour O, Faure P, Ferry N, Garbil B, Larghero J, Nguon M, Pattou F, Thumelin S, Yates F
Therapie, 2015
Uncommon prion disease induced in macaque ten years after scrapie inoculation
Mikol J, Luccantoni-Freire S, Correia E, Lescoutra-Etchegaray N, Durand V, Dehen C, Deslys JP, Comoy E
Neuropathol. Appl. Neurobiol., 2015
PARP-2 depletion results in lower radiation cell survival but cell line-specific differences in poly(ADP-ribose) levels
Boudra MT, Bolin C, Chiker S, Fouquin A, Zaremba T, Vaslin L, Biard D, Cordelieres FP, Megnin-Chanet F, Favaudon V, Fernet M, Pennaneach V, Hall J
Cell. Mol. Life Sci., 2015
Synthetic Scrapie Infectivity: Interaction between Recombinant PrP and Scrapie Brain-Derived RNA
Simoneau S, Thomzig A, Ruchoux MM, Vignier N, Daus ML, Poleggi A, Lebon P, Freire S, Durand V, Graziano S, Galeno R, Cardone F, Comoy E, Pocchiari M, Beekes M, Deslys JP, Fournier JG
Virulence, 2015
Transmission of prions to primates after extended silent incubation periods: Implications for BSE and scrapie risk assessment in human populations
Comoy E, Mikol J, Durand V, Luccantoni S, Correia E, Lescoutra N, Dehen C, Deslys JP
Prion, 2015
Transmission of CWD to non-human primates: Interim results of a 6 year risk assessment study on the transmissibility to humans
Mussil B, Motzkus D, Hesse G, Borchert S, Schiller B, Stahl-Hennig C, Schulz-Schaeffer W, Beekes M, Daus M, Schatzl HM, Dudas S, Yang JM, Deslys JP, Czub S
Prion, 2015
Reversal of mitochondrial defects with CSB-dependent serine protease inhibitors in patient cells of the progeroid Cockayne syndrome
Chatre L, BIARD DSF, Sarasin A, Ricchetti M
Proc. Natl. Acad. Sci. U. S. A., 2015
Transmission of scrapie prions to primate after an extended silent incubation period
Comoy EE, Mikol J, Luccantoni-Freire S, Correia E, Lescoutra-Etchegaray N, Durand V, Dehen C, Andreoletti O, Casalone C, Richt JA, Greenlee JJ, Baron T, Benestad SL, Brown P, Deslys JP
Sci Rep, 2015
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