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Biotechnology and health platforms

Published on 28 June 2016

​Learn about research equipment available to biotech and health companies

Clinatec

​Clinatec

Opened in late 2012, Clinatec is a one-of-a-kind biomedical research centre. On one site it assembles medical doctors, biologists and specialists in micro- and nanotechnologies and electronics from the Grenoble University Hospital Centre, CEA, Université Joseph Fourier and Inserm. This proximity promotes imagining innovative treatments and diagnostic methods and physiopathological research, and greatly facilitates concept demonstration.

The platform’s priorities are cancer, neurodegenerative diseases and handicap. Its surface area of 6,000 square meters brings together 100 researchers and cutting edge equipment in medical imaging, an operating block and six beds. It has received €35 million in funding.

Several firms are involved in this work, including Becton-Dickinson and Tronics.


multimodal imaging platforms

Multimodal imaging platforms

The CEA's Life Sciences Division has cutting-edge expertise in multimodal imaging (magnetic resonance imaging (MRI), positron-emission tomography (PET), and single photon-emission computed tomography (SPECT) and information technology (IT).

This expertise centres on three platforms ranging from preclinical research to clinical research backed by a strong collaborative hospital network.

MirCen is a preclinical imaging centre for developing innovative therapies in the field of neurodegenerative, liver, heart and infectious diseases.

The Service Hospitalier Frédéric Jolliot (SHFJ) is a non-invasive molecular and functional imaging centre dedicated to preclinical and clinical research, including a nuclear medicine unit. It is one of the few centres in France with a research cyclotron and radiochemistry unit. With its teams specialising in methodology and handling of PET and MRI images, SHFJ offers a multimodal approach to biomedical imaging for neurology, psychiatry, oncology, and cardio-vascular and metabolic diseases.
logo neurospin

The goal of the NeuroSpin platform is to observe the brain and its pathologies with ever greater accuracy. In 2013, NeuroSpin received delivery of the first 11.75 tesla whole-body MRI scanner. Construction of the Iseult magnet is part of a Franco-German research programme with major firms in the sector, including Guerbet, Siemens and Alstom.


Genome research platforms

Genome research platforms

The French national genome research platforms, Centre National de Génotypage (CNG) and Centre National de Séquençage (CNS or Génoscope), have been part of CEA since 2007.

These two platforms have the second largest sequencing capacity in Europe with 17 high-speed sequencing machines. The platforms have strong skills in computational biology with a large capacity for analysis, storage and statistical analysis on collected data.

Genoscope has metagenome and enzymatic cloning and screening platforms. This equipment sequences and analyses genetic information from various organisms, giving rise to new applications that can be of scientific, medical or economic interest.

CNG specialises in research into genetics and genetic diseases. Its missions are to identify genetic markers of pathologies (cancer, neurodegenerative and rare diseases). It is a European leader in genotyping with an analytical capacity ranging from 1 to 5×106 different variable positions on the human genome (> 1,000 samples per week).


Structural biology platforms

Structural biology platforms

The Institut de Biologie Structurale (IBS), internationally renowned for its excellence, offers platforms, expertise and skills for the study of the structural and functional organization of proteins. IBS has expertise in the production/characterisation of soluble and membrane proteins, structure determination, and the analysis of macromolecular complexes and interactions.
IBS has cutting edge instruments in crystallography, nuclear magnetic resonance (NMR), mass spectrometry and cryoelectronic microscopy, crystallisation robots, and access to the equipment of its partners ESRF, ILL and EMBL. It plays a leading role in European structural biology research programmes.
IBS assists companies ranging from startups to major pharmaceutical groups with their R&D projects with research agreements or more specific arrangements.


National center

National Center for Infectious Diseases Models and Innovative Therapies (IDMIT)

IDMIT is a research centre dedicated to the development of new vaccines and treatments for infectious diseases. It has cutting edge skills in the preclinical assessment of anti-infection treatments due to its expertise in preparing strongly predictive complex vivo models, which is made available to its industry partners.

IDMIT has leading edge equipment in in vivo imaging, immunoanalysis and immunomonitoring (mass and flow cytometry).



Clinatec building

Clinatec building in Grenoble © P.Avavian/CEA








Neurospin

​3T IRM for clinical studies and whole-body exams
© A.Gonin/CEA


mircen 

SHFJ logo 


Neurospin logo 










View of equipment at CNG

​View of equipment at CNG © F.Rhodes/CEA


Genoscope

CNG 






IBS - 800 MHz very high field NMR spectrometer. Positioning a sample.

​IBS - 800 MHz very high field NMR spectrometer. Positioning a sample. © P.Avavian/CEA