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Fundamental Research Division
The DRF at the CEA assemble approximately 6,000 scientists since January 2016.
In a study at the interface of physics and biology, a team from CEA-BIG has characterized the swimming behavior of bacteria in the vicinity of cells. Their work contributes to an improved understanding of the infectious potential of bacteria, and possibly to the development of a new anti-infective strategy.
An international consortium has set out to find the oldest ice on Earth, in Antarctica, using a revolutionary probe developed by French teams, with early participation by LSCE: Subglacior. The probe makes it possible to date ice in real time without coring.
Two French research teams have recently shown in a rodent model that overexpression of an enzyme capable of eliminating excess cholesterol in the brain can act in a beneficial way on the tau component of the disease to completely correct it.
Key elements of the cytoskeleton, microtubules exhibit fascinating and unexpected mechanical properties, such as adapting to stresses as well as self-repair. Their repair dynamics could inspire materials engineering.
A giant virus from a completely new genus was discovered in a Siberian permafrost sample dating back 30,000 years. Genomics, transcriptomics, proteomics and metagenomics draw a detailed portrait of this new virus, known as Mollivirus sibericum.
Development of a novel therapy that targets stem cells responsible for chronic myeloid leukemia (CML). The first treated patients no longer present a detectable disease more than 5 years after stopping this new treatment, which represents a solid hope for a lasting recovery.
A team from the CEA-IBITECS has participated in the development of a new isotope labeling process to accelerate in vivo studies of drug candidates. The original and unprecedented mechanism of this process was elucidated by computer modeling.
Researchers from the CEA-IRTSV and their partners have revised our understanding of the cellular mechanisms behind the impressive photosynthetic capacity of the unicellular marine organisms known as diatoms. They discovered an unexpected interaction between photosynthesis and respiration.
Cyanobacteria, which use light as a source of energy during photosynthesis, also need to know how to protect themselves from it. Researchers have uncovered a unique mechanism of photoprotection that opens new perspectives for synthetic biology and the production of biomolecules of industrial interest.
A team from the CEA-IBITECS located at the Musée de l'Homme has just determined the complete mitochondrial genome of a steppe bison specimen from a bone fragment dating back 19,000 years, found in the Trois-Frères cave (Ariège).
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.