Bioproduction
Advanced micro-nanotechnologies for bioprocess monitoring and analytical control
This sensing system includes:
- A USP (Up Stream Process) in-line device consisting of a all-in one miniaturized multiparametric platform with electrochemical sensors.
- A DSP (Down Stream Process) functionalized photonic biosensor allowing specific measurement of impurities in real time to control purification process.
This hardware-plus-firmware solution leverages near-sensor compute capabilities to process the sensor data and interface with production equipment.
What it can do
It offers a new approach to managing biomanufacturing processes with cutting-edge monitoring technologies for cell culture, drug substance production and purification steps to obtain a very high level of biomedicine batch quality and a significant increase of productivity. This type of real-time multiparameter sensing could also enable more efficient bioproduction in other industries: - Human, animal, and plant nutrition
- Food manufacturing
- Brewing and distilling
- Cosmetics
- Biofuels
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What makes it unique
The cell culture sensors offers features currently not available with today’s commercially available solutions: - Multiplexed electrochemical sensors
- Smart
- Bioreactor digital twin
- Single unit USP sensor
- Versatile DSP sensor
- Low cost
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Bioproduction demonstrator What’s next?
Future bioproduction needs will require next-generation technologies
development such as optical sensors, electromechanical sensors, artificial
intelligence, algorithms, microfluidic devices, fully in line with CEA expertise.
Partners from Calipso project:
