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A versatile lipid nano-formulation system for biomedical applications
CEA-Leti's Lipidots® technology is a delivery system for therapeutic agents in the context of targeted therapy. Lipidots® are small lipid droplets that transport and deliver active drug compounds via encapsulation. They can also carry biological molecules such as nucleic acids (mRNA, DNA, siRNA, etc.), or proteins and peptides, which have been attached to their surface.
Composition, size, dosage and rheological properties can be tailored to suit target needs. More specifically, Lipidots® have a prolonged plasma circulation time and a specific affinity for the liver, lymph nodes, solid tumors or lipid-rich areas such as atherosclerotic plaques.
At CEA-Leti, research engineers are working on innovative solutions for real-world applications:
Lipidots® technology can be used in a variety of therapies and areas of research:
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.