To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
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From 1/11/2021 to 1/11/2021
Bertrand Thirion (PARIETAL - Inria/CEA/Université Paris-Saclay) will give a talk at NeuroSpin on January 11th.
fMRI has opened the possibility to investigate how brain activity is modulated by behavior. Most studies so far are bound to one single task, in which functional responses to a handful of contrasts are analyzed and reported as a group average brain map. By contrast, recent data-collection efforts have started to target a systematic spatial representation of multiple mental functions. In this presentation, we leverage the Individual Brain Charting (IBC) high-resolution task-fMRI dataset acquired in a fixed environment, in order to study the feasibility of individual mapping. We discuss the definition of brain regions given their functional activity, called functional fingerprint. We confirm that the elementary spatial components, inferred across all tasks, are consistently mapped within and, to a lesser extent, across participants. We then demonstrate the relevance of the topographic information of the individual contrast maps, showing that contrasts from one task can be predicted by contrasts from other tasks. Finally, we delineate the cognitive profile of functional territories pertaining to the language network and prove that these profiles generalize across participants.
Alessandro Farnè (Centre de Recherche en Neurosciences de Lyon - CRNL)
Stefano PALMINTERI (ENS, Laboratoire de Neurosciences cognitives)
Jean-Pierre MOTHET (Université Paris-Saclay, LuMIn Lumière Matière et Interfaces)
Silvia BUNGE (UC Berkeley Psychology)
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.