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To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
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An I2BC team has studied, using both in vitro and in silico approaches, the dynamics of phosphatidylserine transport between the endoplasmic reticulum and the plasma membrane in the yeast S. cerevisiae. Their study reveals that the protein Ist2 exhibits lipid scramblase activity and identifies a functional partnership between Ist2 and the lipid transfer protein Osh6.
Researchers from DMTS designed bifunctional PROTAC chemical probes to identify the molecular target(s) of Retro-2 compounds, broad-spectrum inhibitors of intracellular pathogens. Although this approach did not identify new Retro-2 targets, it revealed a molecular glue effect involving the protein GSPT1.
A team from NeuroSpin measured brain connectivity patterns using functional MRI data from a deep-phenotyping dataset involving several tasks (watching movies, listening to stories). The authors showed that sparse partial correlation is more effective for identifying individuals, whereas standard correlation performs better for distinguishing and classifying different cognitive tasks
The COVID-PATH project was officially launched on March 12, 2025, to investigate the gastrointestinal impact of SARS-CoV-2 and its link to Long COVID.
As a stakeholder in the NOMATEN Centre of Excellence for innovative multifunctional materials, the CEA-Joliot Institute supports its development by regularly organizing training sessions for its staff. The latest examples.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.