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Scientific result | Chemistry | Cancer

Functionalized micellar nanovectors for targeted tumor therapy


​As part of a collaboration with MIRCen (François Jacob Institute of Biology) and SBIGeM, SCBM researchers have developed functional micellar nanovectors capable of targeting a population of cancer cells.

Published on 12 April 2018

​Abstract

Polydiacetylene micelles were functionalized with controlled amounts of biotin using bioorthogonal click chemistry. The biotinylated micelles were evaluated in the selective targeting of the MCF-7 cancerous cell line and were shown to be readily internalized. The efficiency of the cellular uptake was correlated to the density of grafted biotin.

Read the French version.

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