To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
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Laboratory | Bioinformatic | Genomics | Epigenetics
The group is interested in molecular mechanisms of eukaryotic transcriptional regulation in vivo on the genomic scale. The Mediator complex, essential for regulation of transcription by RNA polymerase II, is central for our projects. We use the budding yeast Saccharomyces cerevisiae and human cells as our biological models and apply integrative approaches to understand how the transcriptional regulation works and how transcription is coordinated with others nuclear processes like DNA repair.
This team is part of I2BCVersion Française
Team LeaderJulie SOUTOURINA+33 1 69 08 54 13Julie.Soutourina@Cea.Fr
"We are now interested in the role of Mediator in transcription activation and, in particular, in preinitiation complex formation."
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.