 | | Orchestration of human multi-lineage hematopoietic cell development by humanized in vivo bone marrow models | Renou L, Sun W, Friedrich C, Galant K, Conrad C, Consalus A, Plantier E, Schallmoser K, Krisch L, Barroca V, Devanand S, Dechamps N, Reinisch A, Martinovic J, Magnani A, Faivre L, Lewandowski D, Calvo J, Perie L, Kosmider O, Pflumio F
| | | | | DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria. | Dalia, T.N., Machouri, M., Lacrouts, C., Fauconnet, Y., Guerois, R., Andreani, J.*, Radicella, J.P.*, Dalia, A.B.* (* co-corresponding authors)
| | | | | Progressive chromatin rewiring by ETO2::GLIS2 revealed in a genome-edited human iPSC model of pediatric leukemia initiation | Boudia F, Baille M, Babin L, Aid Z, Robert E, Rivière J, Galant K, Alonso-Pérez V, Anselmi L, Arkoun B, Abermil N, Marzac C, Bertuccio SN, de Prémesnil A, Lopez CK, Eeckhoutte A, Naimo A, Leite B, Catelain C, Metereau C, Gonin P, Gaspar N, Schwaller J, Bernard OA, Raslova H, Gaudry M, Marchais A, Lapillonne H, Petit A, Pflumio F, Arcangeli ML, Brunet E, Mercher T
| | | | | High CD44 expression and enhanced E-selectin binding identified as biomarkers of chemoresistant leukemic cells in human T-ALL | Calvo J, Naguibneva I, Kypraios A, Gilain F, Uzan B, Gaillard B, Bellenger L, Renou L, Antoniewski C, Lapillonne H, Petit A, Ballerini P, Mancini SJ, Marchand T, Peyron JF, Pflumio F
| | | | | The AXL inhibitor bemcentinib overcomes microenvironment-mediated resistance to pioglitazone in acute myeloid leukemia | Zhu J, Guérineau H, Lefebvre-Fortané AM, Largeaud L, Lambert J, Rousselot P, Boudouin M, Calvo J, Prost S, Clauser S, Bardet V
| | | | | Developmental interplay between transcriptional alterations and a targetable cytokine signaling dependency in pediatric ETO2::GLIS2 leukemia | Alonso-Pérez V, Galant K, Boudia F, Robert E, Aid Z, Renou L, Barroca V, Devanand S, Babin L, Rouiller-Fabre V, Moison D, Busso D, Piton G, Metereau C, Abermil N, Ballerini P, Hirsch P, Haddad R, Martinovic J, Petit A, Lapillonne H, Brunet E, Mercher T, Pflumio F
| | | | | Multiple Mechanisms of Action of Sulfodyne®, a Natural Antioxidant, against Pathogenic Effects of SARS-CoV-2 Infection | Romeo PH, Conquet L, Messiaen S, Pascal Q, Moreno SG, Bravard A, Bernardino-Sgherri J, Dereuddre-Bosquet N, Montagutelli X, Le Grand R, Petit V, Ferri F
| | | | | T-cell acute lymphoblastic leukemia progression is supported by inflammatory molecules including hepatocyte growth factor | Le Maout C, Fahy L, Renou L, Devanand C, Duwat C, Barroca V, Le Gall M, Ballerini P, Petit A, Calvo J, Uzan B, Pflumio F, Petit V
| | | | | The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300-dependent stemness program | Fagnan A, Aid Z, Baille M, Drakul A, Robert E, Lopez CK, Thirant C, Lecluse Y, Rivière J, Ignacimouttou C, Salmoiraghi S, Anguita E, Naimo A, Marzac C, Pflumio F, Malinge S, Wichmann C, Huang Y, Lobry C, Chaumeil J, Soler E, Bourquin JP, Nerlov C, Bernard OA, Schwaller J, Mercher T
| | | | | CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia | Cardoso BA, Duque M, Gírio A, Fragoso R, Oliveira ML, Allen JR, Martins LR, Correia NC, Silveira AB, Veloso A, Kimura S, Demoen L, Matthijssens F, Jeha S, Cheng C, Pui CH, Grosso AR, Neto JL, De Almeida SF, Van Vlieberghe P, Mullighan CG, Yunes JA, Langenau DM, Pflumio F, Barata JT
| | | | | Identifying Candidate Gene Drivers Associated with Relapse in Pediatric T-Cell Acute Lymphoblastic Leukemia Using a Gene Co-Expression Network Approach | Kypraios A, Bennour J, Imbert V, David L, Calvo J, Pflumio F, Bonnet R, Couralet M, Magnone V, Lebrigand K, Barbry P, Rohrlich PS, Peyron JF
| | | | | Targeted nuclear irradiation with a proton microbeam induces oxidative DNA base damage and triggers the recruitment of DNA glycosylases OGG1 and NTH1. | Robeska, E., Lalanne, K., Vianna, F., Sutcu, H.H., Khobta, A., Busso, D., Radicella, J.P., Campalans, A.*, Baldeyron, C.*. (* co-corresponding authors)
| | | | | A R-loop sensing pathway mediates the relocation of transcribed genes to nuclear pore complexes. | Penzo A, Dubarry M, Brocas C, Zheng M, Mangione RM, Rougemaille M, Goncalves C, Lautier O, Libri D, Simon MN, Géli V, Dubrana K, Palancade B. | | | | | All roads lead to MRN regulation at telomeres: different paths to one solution. | Roisné-Hamelin F & Marcand S | | | | | Congenital mirror movements are associated with defective polymerization of RAD51. | Trouillard O., Dupaigne P., Dunoyer M., Doulazmi M., Herlin M.K., Frismand S., Riou A., Legros V., Chevreux G., Veaute X., Busso D., Fouquet C., Saint-Martin C., Ménetret A., Trembleau A., Dusart I., Dubacq C., Roze E. | | | | | DOT1L regulates chromatin reorganization and gene expression during sperm differentiation. | Blanco M, El Khattabi L, Gobé C, Crespo M, Coulée M, de la Iglesia A, Ialy-Radio C, Lapoujade C, Givelet M, Delessard M, Seller-Corona I, Yamaguchi K, Vernet N, Van Leeuwen F, Lermine A, Okada Y, Daveau R, Oliva R, Fouchet P, Ziyyat A, Pflieger D, Cocquet J. | | | | | Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells | D’Augustin, O., Gaudon, V., Siberchicot, C., Smith, R., Chapuis, C., Depagne, J., Veaute, X., Busso, D., Di Guilmi, A.M., Castaing, B., Radicella, J.P., Campalans, A.*, Huet, S* (co-corresponding authors) | | | | | The Antioxidant TEMPOL Protects Human Hematopoietic Stem Cells From Culture-Mediated Loss of Functions | Elia Henry, Frédéric Picou, Vilma Barroca, Nathalie Dechamps, Steicy Sobrino, Emmanuelle Six, Camille Gobeaux, Patrick Auberger, Olivier Hérault, Françoise Pflumio, Marie-Laure Arcangeli | | | | | Rad51 filaments assembled in the absence of the complex formed by the Rad51 paralogs Rad55 and Rad57 are outcompeted by translesion DNA polymerases on UV-induced ssDNA gaps | Maloisel L., Ma E., Phipps J., Deshayes A., Mattarocci S., Marcand S., Dubrana K., Coïc E. | | | | | A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors | Marques Da Costa ME, Zaidi S, Scoazec JY, Droit R, Lim WC, Marchais A, Salmon J, Cherkaoui S, Morscher RJ, Laurent A, Malinge S, Mercher T, Tabone-Eglinger S, Goddard I, Pflumio F, Calvo J, Redini F, Entz-Werlé N, Soriano A, Villanueva A, Cairo S, Chastagner P, Moro M, Owens C, Casanova M, Hladun-Alvaro R, Berlanga P, Daudigeos-Dubus E, Dessen P, Zitvogel L, Lacroix L, Pierron G, Delattre O, Schleiermacher G, Surdez D, Geoerger B. | | | | | In vivo reduction of RAD51-mediated homologous recombination triggers aging but impairs oncogenesis. | Matos-Rodrigues G, Barroca V, Muhammad AA, Dardillac E, Allouch A, Koundrioukoff S, Lewandowski D, Despras E, Guirouilh-Barbat J, Frappart L, Kannouche P, Dupaigne P, Le Cam E, Perfettini JL, Romeo PH, Debatisse M, Jasin M, Livera G, Martini E & Lopez BS. | | | | | Deciphering the immune reaction leading to spontaneous melanoma regression: initial role of MHCII+ CD163- macrophages | Blanc F, Bertho N, Piton G, Leplat JJ, Egidy G, Bourneuf E, Vincent-Naulleau S, Prévost-Blondel A | | | | | Spatio-temporal dynamics of the DNA glycosylase OGG1 in finding and processing 8-oxoguanine | Cintori, L., Di Guilmi, A.M., Canitrot, Y., Huet, S., Campalans, A | | | | | Fetal Muse-based therapy prevents lethal radio-induced gastrointestinal syndrome by intestinal regeneration | Dushime H, Moreno SG, Linard C, Adrait A, Couté Y, Peltzer J, Messiaen S, Torres C, Bensemmane L, Lewandowski D, Romeo PH, Petit V, Gault N
| | | | | Switching of RNA splicing regulators in immature neuroblasts: a key step in adult neurogenesis | Corentin Bernou, Marc-André Mouthon, Mathieu Daynac, Benjamin Demaille, Vilma Barroca, Sébastien Couillard-Despres, Nathalie Déchamps, Véronique Ménard, Léa Bellenger, Christophe Antoniewski, Alexandra Chicheportiche, François D. Boussin | | | | | A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner. | Ragu S, Droin N, Matos-Rodrigues G, Barascu A, Caillat S, Zarkovic G, Siberchicot C, Dardillac E, Gelot C, Guirouilh-Barbat J, Radicella JP, Ishchenko AA, Ravanat JL, Solary E, Lopez BS | | | | | Chelation therapy with 3,4,3-Li(1,2-HOPO) after pulmonary exposure to plutonium in rats. | Grémy O, Devilliers K, Miccoli L | | | | | Ovarian tissue cryopreservation can be combined simultaneously with oocyte retrieval after controlled ovarian hyperstimulation. | Puy V, Dupeux M, Mayeur A, Grynberg M, Benoit A, Bendayan M, Zhegari F, Hesters L, Gallot V, Prevot S, Frydman N, Sonigo C | | | | | Take a Swipe at Actinide Bioavailability: Application of a New In Vitro Method. | Griffiths NM, Moureau A, Coudert S, Huet F, Defrance M, Van der Meeren A | | | | | The neural addiction of cancer. | | | |
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