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The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
Find here all the scientific news and highlights about the François Jacob Institute of Biology.
In response to the global rise of bacteria that are extremely resistant to antibiotics researchers from the IDMIT Department have developed monoclonal antibodies capable of neutralizing Klebsiella pneumoniae in vitro and in vivo.
In September 2025, the ATLASea research program, led by CEA/Genoscope and CNRS, reached a major milestone: 100 marine species genomes have been sequenced. This achievement highlights the momentum of this national project, launched in 2023, which aims to map the genetic heritage of 4,500 marine eukaryotic species found in French waters.
Researchers at IDMIT, in collaboration with IRBA, have demonstrated in a preclinical model of sexually transmitted monkeypox that the MVA vaccine provides effective protection when administered as pre-exposure prophylaxis but does not confer protection when given post-exposure.
Researchers from IRCM have published findings on the internalization of metallic nanoparticles in cancer cells. These results could be used to target the most aggressive and treatment-resistant tumor cells.
Researchers at Genoscope have developed a spatial mapping technique based on a molecularly barcoded DNA chip, enabling the decoding of epigenomic signatures and the identification of regulatory changes in gene expression within tissue sections.
Researchers from IRCM have identified a C-terminal segment of the Rad52 protein that plays an essential chaperone role in the formation and stabilization of Rad51 filaments, which are crucial for DNA repair through homologous recombination.
Researchers from IRCM, in collaboration with I2BC and Indiana University, reveal in PNAS the essential role of two proteins in the progression of antibiotic resistance.
Researchers at IRCM have developed and characterized in vivo humanized bone marrow models. These results open up new perspectives for research on leukemia, on protective interactions between cancer cells and bone marrow cells, and may help to pave the way for personalized therapies.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.
