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The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
Find here all the scientific news and highlights about the François Jacob Institute of Biology.
Researchers from IRCM have published findings on the internalization of metallic nanoparticles in cancer cells. These results could be used to target the most aggressive and treatment-resistant tumor cells.
Researchers at Genoscope have developed a spatial mapping technique based on a molecularly barcoded DNA chip, enabling the decoding of epigenomic signatures and the identification of regulatory changes in gene expression within tissue sections.
Researchers from IRCM have identified a C-terminal segment of the Rad52 protein that plays an essential chaperone role in the formation and stabilization of Rad51 filaments, which are crucial for DNA repair through homologous recombination.
Researchers from IRCM, in collaboration with I2BC and Indiana University, reveal in PNAS the essential role of two proteins in the progression of antibiotic resistance.
Researchers at IRCM have developed and characterized in vivo humanized bone marrow models. These results open up new perspectives for research on leukemia, on protective interactions between cancer cells and bone marrow cells, and may help to pave the way for personalized therapies.
Researchers from IDMIT Department has developed a PET imaging strategy to visualize and quantify the distribution of SARS-CoV-2 throughout the whole body in a non-human primate model. These findings were published in Nature Communications.
Researchers from Mircen contributed to a study published in Brain, showing in a mouse model the role of a gene, DLCK3, in modulating anxiety and memory.
In a study published in Nucleic Acids Research (NAR), researchers from IRCM reveal fine-tuned mechanisms regulating the transition of germ cells from mitosis to meiosis during mouse spermatogenesis, providing new insights into certain forms of male infertility.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.