To access all features of this site, you must enable Javascript. Here are the instructions for enabling Javascript in your web browser.
To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
All the news of the Institute of life sciences Frédéric Joliot
Cyclodipeptide synthases (CDPSs) have been discovered in 2009 by the IBITECS team. They constitute a remarkable enzymes family, with a wide variety of products and pharmacological activities. Here, is described the activity of 41 new CDPSs.
Photosynthetic organisms protect themselves from too much light using pigment photoswitches that absorb excess energy. American scientists (Berkeley, Michigan State University) and French researchers (SB2SM team) analyzed the structure of an active, energy-dissipating form of the orange carotenoid protein (OCP) from a cyanobacterium.
A study, coordinated by a SBIGeM team in collaboration with a SB2SM team, allowed to describe the role of the Hug1 protein in regulating the activity of the ribonucleotide reductase complex (RNR). The level of active RNR is controlled during cell cycle and in response to DNA damages.
Certain mobile DNA sequences shape genomes and are maintained over the course of generations. How is this explained? The interaction between two proteins, which is essential for their integration into a specific area of the yeast genome, has been identified. This finding has interesting implications for gene therapy.
Teams of IBITECS and Ecole Polytechnique (Palaiseau) have deciphered the mechanism used by the cyclodipeptide synthases (CDPS) to catalyze the formation of peptide bonds.
Friedreich's ataxia is a severe neurodegenerative disease caused by the decreased expression of frataxin, a mitochondrial protein that stimulates iron–sulfur (Fe-S) cluster biogenesis.
People afflicted with microcephaly have undersized brains. Researchers from the CEA-I2BM have developed a mathematical analysis of MRI images that can discriminate variations in cortical folding complexity. This is a methodological step towards a more effective diagnostic approach, as well as a better understanding of cerebral development.
Why are we not aware of external noises while we sleep? A study by the CEA-I2BM shows that even if the sounds still penetrate into the auditory cortex, sleep disrupts the brain’s ability to anticipate.
Top page
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.