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To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
All the news of the Institute of life sciences Frédéric Joliot
Researchers from the CEA-IBITECS in collaboration with a team from the University of Strasbourg (UDS) have developed new reagents known as “chelating azides”, which can rapidly and selectively couple to any compound equipped with an alkyne group. The reaction can take place in any environment, including within a cell.
A team from the CEA-IBITECS participated in the identification of a novel role for an enzyme, the protease MMP-12, in the immune response to viral infection. The researchers developed an inhibitor of MMP-12, which enhances the immune response in a rodent model. This work, opens the way for the development of new antiviral therapies.
An Anglo-French team (AP-HP, Inserm, CEA/Mircen, UPEC, Oxford Biomedica, Cambridge University) coordinated by Professor Stéphane Palfi (head of the neurosurgery department at the hôpital Henri-Mondor) conducted a gene therapy trial in 15 patients with an advanced form of Parkinson’s disease.
Brain anatomy plays a major role in cognitive control, a key skill in learning and academic success. This finding is the result of research carried out by the Laboratory for the Psychology of Child Development and Education (CNRS/Université Paris Descartes/Université de Caen Basse-Normandie), in collaboration with the NeuroSpin imaging center (CEA).
CEA Teams from the CEA-iBiTec-S and the CEA-Iramis have developed a technique to rapidly make large quantities of probes for xenon MRI. These specific probes are able to target a desired molecule to be observed, such as a protein involved in a particular disease.
A research team led by Denis Le Bihan (CEA) at the NeuroSpin neuroimaging center has just demonstrated that water diffusion slows down in activated regions of the brain.
Thanks to a high-field MRI scanner, researchers from the CEA-I2BM followed the dynamics of ion exchange in neurons, which conduct the propagation of nerve impulses.
Researchers from the CEA-iBiTec-S have developed rapid detection tests against the plague-causing agent Yersinia pestis, to detect the bacillus in the environment. Because plague has not yet been eradicated.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.