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Frédéric-Joliot Institute for Life sciences

Frédéric Joliot Institute for Life Sciences

  • Frédéric Joliot Institute for Life Sciences
  • The Institute
  • Research entities
  • Platforms & Infrastructures
  • Funding & TTO
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Presentation of the Institute

  • Presentation of the Institute
  • Research Themes
    • Integrative Biology of the Cell
    • Biomedical Imaging
    • Diagnostic and Therapeutic Innovation
  • Doing a PhD at the Frédéric Joliot Institute
    • PhD dissertations
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Consult the section « The Institute »

Research Entities

  • I2BC@SACLAY
    • Integrative Biology and Molecular Genetics Unit - SBIGeM
    • Bioenergetics, Structural Biology and Mechanisms Unit - SB2SM
    • I2BC@Saclay Department Platforms
  • DMTS
    • Molecular labeling and bio-organic chemistry Unit - SCBM
    • Pharmacology and Immunoanalysis Unit - SPI
    • Molecular engineering for Health Unit - SIMoS
    • Medicines and Healthcare Technologies Department Platforms
  • NeuroSpin
    • Recherche volontaires
    • BAOBAB
    • Translational and Applicative Neuroimaging Research Unit - UNIACT
    • Cognitive Neuroimaging Unit - UNICOG
    • Inria / CEA MIND (formerly PARIETAL)
    • Neurofunctional Imaging Group - GIN (Bordeaux)
    • NeuroSpin Platform
    • Monday Conferences
    • Practical information
  • SHFJ
    • Nuclear Medicine Service
    • BioMaps
    • Laboratory for Methodological Developments in PET
    • TIRO-MATOS (Nice)
    • SHFJ Platforms
    • Practical information
Consult the section « Research entities »

Platforms and Infrastructures

To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...

  • The Institute within National Infrastructures in Biology and Health
    • FLI
    • FRISBI
    • MetaboHUB
    • NeurATRIS
  • Institute's platforms
    • In vivo imaging
    • Mass spectrometry analysis
    • Chemistry and molecular labeling
    • Bioproduction and functional exploration
    • Biophysics and bioinformatics
Consult the section « Platforms & Infrastructures »

Funding & TTO

  • Europe
    • ERC
    • EIT Health
    • Research & Innovation Actions (RIA)
    • ITN
    • Coordination and Support Actions
  • Industrial cooperation
Consult the section « Funding & TTO »

​News from the Frédéric Joliot Institute for Life Sciences

​All the news of the Institute of life sciences Frédéric Joliot

  • Scientific news
  • Institutional news
  • Events
  • Press Area
Consult the section « News »
  • Contact us
  • French site
  • Mitosis: condense to better attach

    A study led by the I2BC shows that the formation of condensates of the enzyme KIF2C enables the concentration of two other proteins, PLK1 and phosphorylated BRCA2, on kinetochore microtubules during mitosis. This would serve to control chromosome alignment on the spindle and contribute to their stability.

    Mitosis: condense to better attach
  • Ultrasound to counter the effects of exposure to a neurotoxic agent

    Researchers from BioMaps (SHFJ), NeuroSpin, and the french IRBA developed an innovative approach using focused ultrasound to improve brain delivery of an antidote, oxime, following exposure to an organophosphorus neurotoxic agent in a murine model.

    Ultrasound to counter the effects of exposure to a neurotoxic agent
  • Monitoring microstructural and functional brain development in infants using multimodal MRI.

    A team from NeuroSpin studied the microstructural and functional connectivity profiles of infants’ brains to understand how these characteristics evolve and relate to each other during early neurodevelopment. The results indicate that connectivity, which is altered by prematurity, strengthens with maturation, and that the associated networks become increasingly similar.

    Monitoring microstructural and functional brain development in infants using multimodal MRI.
  • Grâce à de petits motifs dans une séquence désordonnée, Rad52 organise l’assemblage de Rad51

    En utilisant Saccharomyces cerevisiae comme modèle, des chercheurs des instituts CEA-Jacob et CEA-Joliot, et de l’Institut Curie, avec leurs partenaires du synchrotron SOLEIL, ont révélé comment la protéine Rad52 agit comme un chaperon pour guider et stabiliser l’assemblage de Rad51, une étape clé de la recombinaison homologue.​

    Grâce à de petits motifs dans une séquence désordonnée, Rad52 organise l’assemblage de Rad51
  • Statistical learning beyond words in human neonates

    Ghislaine Dehaene's team (NeuroSpin) carried out EEG experiments on neonates to find out whether statistical learning was a mechanism dedicated solely to language acquisition. By exploiting the speaker identity and phonemes, the researchers conclude that statistical learning mechanisms are universal and not limited to linguistic characteristics.

    Statistical learning beyond words in human neonates
  • A drug candidate for the treatment of neonatal encephalopathy

    Researchers from the SPI (DMTS) and the Women & Infants Hospital in Providence have laid the molecular basis for the neuroprotection of a purine derivative in a preclinical model of neonatal hypoxic-ischemic encephalopathy (HIE). The promising results support the development of this drug candidate to treat HIE in neonates.

    A drug candidate for the treatment of neonatal encephalopathy
  • L'IRM de diffusion pour étudier des altérations de la substance blanche dans la maladie d’Alzheimer et la pathologie LATE ?

    Des chercheurs du SHFJ, de NeuroSpin et du GHU Paris Psychiatrie & Neurosciences mettent en évidence des différences dans les altérations des faisceaux de substance blanche entre des patients diagnostiqués Alzheimer et d’autres vraisemblablement atteints de la pathologie LATE.

    L'IRM de diffusion pour étudier des altérations de la substance blanche dans la maladie d’Alzheimer et la pathologie LATE ?

Last institutional news (82 documents)

RSS feed

  •    A GMR-sensor biochip for point-of-care diagnostics A GMR-sensor biochip for point-of-care diagnostics
  •    Nanobodies, new therapeutic avenues against schizophrenia Nanobodies, new therapeutic avenues against schizophrenia
  •    Unprecedented method for monoclonal antibodies production through targeted cell fusion Unprecedented method for monoclonal antibodies production through targeted cell fusion
  •    New technique for analyzing polarized light-emitting molecules New technique for analyzing polarized light-emitting molecules
  •    Better understanding opioid tolerance through brain imaging Better understanding opioid tolerance through brain imaging
  •    Correlation of neuroinflammation and epileptogenic zone in drug-resistant epilepsy Correlation of neuroinflammation and epileptogenic zone in drug-resistant epilepsy

Press Area

  • A world premiere: the living brain imaged with unrivaled clarity thanks to the world’s most powerful MRI machine
    2 April 2024 A world premiere: the living brain imaged with unrivaled clarity thanks to the world’s most powerful MRI machine

    ​The CEA is revealing a series of in vivo human brain images acquired with the Iseult MRI machine and its unmatched 11.7 teslas magnetic field strength. This success is the fruit of more than 20 years of R&D as part of the Iseult project, with one pillar goal being to design and build the world’s most powerful MRI machine. Its ambition is to study healthy and diseased human brains with an unprecedented resolution, allowing us to discover new details relating to the brain’s anatomy, connections, and activity.

  • The New York Times is interested in the studies on the sensitivity to geometry conducted at NeuroSpin
    31 March 2022 The New York Times is interested in the studies on the sensitivity to geometry conducted at NeuroSpin

    In an article in the New York Times, Stanislas Dehaene (NeuroSpin director) and Mathias Sablé-Meyer (PhD student) discuss recent results obtained in collaboration with the Collège de France, the CNRS and the University of Paris 8 that show that humans have a universal capacity to understand abstract geometric concepts.

  • The most powerful MRI scanner in the world delivers its first images
    7 October 2021 The most powerful MRI scanner in the world delivers its first images

    September 2021, the 11.7 Tesla MRI of the Iseult project, the most powerful in the world for human imaging, has just unveiled its first images.

All Press Releases  

Other news

  • 29 January 2021 The “Extended-Personal Reality”: augmented recording and transmission of virtual senses through artificial-IntelligENCE

    Le projet EXPERIENCE cherche à utiliser la réalité virtuelle pour améliorer la vie quotidienne en permettant de nouvelles formes d’interaction sociale et d’expression personnelle.

​
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