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The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
What are the mechanisms preventing viral progression in HIV "elite controllers"? Researchers at the François Jacob Institute of Biology and their partners have shed light on some particularities of CD8+ T cells.
In a 100-patient cohort at the Saint-Louis Hospital in Paris, researchers from the CEA and Paris-Diderot University have shown that the rate of certain immune cells in the blood is predictive of bladder cancer recurrence or progression. They suggest using their patented blood test to predict recurrence in other types of cancers.
A team from the CEA François-Jacob Institute has demonstrated the preclinical efficacy of three vaccine candidates against chikungunya.
Joint damage in people infected with chikungunya remains poorly understood. Scientists from the CEA François-Jacob Institute and their partners have identified an actor of the antiviral immune response whose inhibition paradoxically reduces the severity of the symptoms.
A patient with severe sickle cell disease has undergone gene therapy developed at the CEA François-Jacob Institute. Two years after treatment, the remission of clinical signs was complete.
In a phase 2 clinical trial, scientists showed the efficiency of targeting cancer stem cells—an approach imagined and developed at the CEA François-Jacob Institute for the treatment of leukemia, chronic myeloid leukemia in particular.
Scientists at the CEA’s Institute of Cellular and Molecular Radiation Biology, in collaboration with INSERM, Université Paris-Sud, and international partners, have demonstrated a connection between the expression of the TRAIL gene, which plays a role in cell death, and the radiosensitivity of certain human T lymphocytes.
The network of planktonic organisms of this carbon sink has been described as a social network by an interdisciplinary team comprising oceanographers, biologists and computer experts mainly from the CNRS, UPMC, University of Nantes, VIB, EMBL and CEA.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.