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To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
All the news of the Institute of life sciences Frédéric Joliot
NeuroSpin researchers map chimpanzee brain structural connectivity for the first time using diffusion MRI data. New image processing enabled them to create two atlases of deep and superficial white matter connectivity. A step towards a better understanding of the evolution of the hominid brain.
In a study published in Nature Communications, researchers from UNICOG and BAOBAB use high-field functional MRI to reveal the brain areas where the representations of quantities generated by a mental arithmetic operation are encoded.
In an article published in Nature Communications, researchers from the I2BC show that applying a fragmentation strategy to the protein partners of assemblies depending on intrinsically disordered regions very significantly improves AlphaFold2's prediction capacity.
Les dispositifs tels que les lampes et les lunettes stroboscopiques censés faciliter la lecture des personnes dyslexiques n’auarient en fait aucun impact. C’est ce que révèle une étude menée par une équipe d’UNICOG (NeuroSpin) et publiée dans la revue Proceedings Royal Society.
Researchers at SIMoS (DMTS) describe the synthesis, engineering and evaluation of the properties of the B subunit of bacterial Shiga toxin (STxB), administered mucosally, as a vaccine tool. Their results confirm the value of using a synthetic STxB in an anti-tumor and anti-infectious vaccination strategy.
SHFJ researchers have validated the use of a new biomarker, the nonlinear shear modulus, to measure the elasticity of biological tissues, by comparing results obtained using echography with those obtained using MRI imaging and digital simulation. This biomarker is of particular interest for the diagnosis of certain breast cancers.
Une étude menée par le laboratoire Biomaps (SHFJ) apporte de premiers éléments pour considérer la TEP au radiotraceur [18F] DPA-714 comme un outil supplémentaire pour la bonne localisation préchirurgicale des zones épileptogènes chez les patients atteints d’une épilepsie pharmaco-résistante.
Des chercheurs du SIMoS montrent que la combinaison de deux approches in silico et in vitro permet de sélectionner des anticorps thérapeutiques dont la fonctionnalité est préservée tout en diminuant le risque qu’ils induisent une réponse immunitaire indésirable.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.