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Highlight | News | Infectious diseases
With the support of the Ministry of Solidarity and Health and the Ministry of Higher Education, Research and Innovation, 20 scientific initiatives were selected by REACTing's scientific board and presented at a press conference on 11 March. Among them, IDMIT is piloting a fundamental research project on the evolution of Covid-19 in a specific pre-clinical study model.
As the the Sars-CoV2 coronavirus epidemic continues to
spread, the Alliance for Life Sciences and Health (Aviesan) is mobilizing to
accelerate research on the virus and on the disease COVID-19, through the
action of the REACTing consortium, coordinated by Inserm. With the support of
the Ministry of Solidarity and Health and the Ministry of Higher Education,
Research and Innovation, 20 scientific initiatives have been selected by the
REACTing scientific council. They cover themes as diverse as epidemic
modelling, treatment research and prevention.
Aviesan is made up of 9 key academic players, founding
members of Aviesan: CEA, CNRS, INRAE, INRAE, Inria, Inserm, Pasteur Institute,
IRD, CPU and the Conference of Regional and University Hospital CEOs. The
REACTing consortium is coordinated by Inserm.
Following a call for applications from all French research
teams, the scientific council of REACTing, a genuine research accelerator
consortium, selected 20 projects from various scientific disciplines. These
were chosen for their exhaustive and effective contribution to the production
of knowledge and for their contribution to the fight against this new epidemic.
These projects fall within the following four main
scientific themes: human and social sciences; diagnostic, clinical and
therapeutic research; epidemiological research and basic research with a
Three basic research projects have been selected, in
particular to better understand the context of virus replication in vitro.
IDMIT, (François Jacob Institute of Biology), is leading one
of these three projects. Its missions will be to study the evolution of
infection by the new virus in a primate animal model to monitor the progression
of the disease, test prophylactic treatments with drugs already on the market
or in the process of being marketed, and develop new vaccines before their
implementation in humans.
Thanks to its experience and research on infectious diseases
such as influenza, measles, chikungunya, etc., IDMIT has the expertise in
virology and immunology, as well as the necessary facilities (A3 primate animal rooms with an area dedicated to aerosol-transmitted pathogens) to carry out
these studies. IDMIT is part of a group of experts mandated at the global level
by the WHO (World Health Organization).
The coronavirus strains used for the assessments are
provided by the Pasteur Institute (Paris), National Reference Centre for
Respiratory Infection Viruses.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.