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The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
In a study published in JCI Insight, researchers from IDMIT have demonstrated the vaccinal effectiveness of serum transfers from volunteers vaccinated against the chikungunya virus to an animal model. This work is an important step toward vaccine marketing approval, as the nature of chikungunya epidemics hampers the deployment of conventional efficacy trials.
For a study they published in Nature Communications, researchers from the CNRGH and PARCC joined forces to unprecedentedly identify genome loci associated with a risk of primary hyperaldosteronism (PHA), the most frequent cause of secondary arterial hypertension.
In a work published in Scientific Reports, researchers from IRCM, the Sup'Biotech/SEPIA partnership lab and Imagine Institute teamed to develop an in vitro, model of infertility wherein induced pluripotent stem cells generated from the erythroblasts of infertile men presenting genetic abnormalities were used to successfully generate primordial germ-like cells.
In a new collaborative study published in Scientific Reports, researchers from the Gly-CRRET Laboratory (UPEC) and SEPIA (CEA-Jacob) deployed a novel cellular model to describe the induction of the autonomous abnormal aggregation of tau protein following the expression of HS3ST2.
Researchers from IDMIT describe the course of immune & inflammatory markers and the vaginal microbiome during the menstrual cycle.
With massively parallel sequencing of DNA collected from the surfaces of the earth's oceans and seas (Tara Oceans expeditions) and more than ten years of analysis, an international team piloted by researchers from Genoscope (CEA-Jacob) and the CNRS has solved one of environmental biology's greatest puzzles.
A team of researchers from IRCM (CEA-Jacob) and I2BC have shed light on the role of ComFC, a bacterial protein involved in natural transformation, itself a driving mechanism for the propagation of antibiotic resistance genes and virulence factors.
In an article published in Cell Reports, an international team including researchers from MIRCen showed that a cerebral network associated with highly elaborate cognitive capacities in humans differs from the comparable network in non-human primates.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.