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The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
In a work published in Scientific Reports, researchers from IRCM, the Sup'Biotech/SEPIA partnership lab and Imagine Institute teamed to develop an in vitro, model of infertility wherein induced pluripotent stem cells generated from the erythroblasts of infertile men presenting genetic abnormalities were used to successfully generate primordial germ-like cells.
In a new collaborative study published in Scientific Reports, researchers from the Gly-CRRET Laboratory (UPEC) and SEPIA (CEA-Jacob) deployed a novel cellular model to describe the induction of the autonomous abnormal aggregation of tau protein following the expression of HS3ST2.
Researchers from IDMIT describe the course of immune & inflammatory markers and the vaginal microbiome during the menstrual cycle.
With massively parallel sequencing of DNA collected from the surfaces of the earth's oceans and seas (Tara Oceans expeditions) and more than ten years of analysis, an international team piloted by researchers from Genoscope (CEA-Jacob) and the CNRS has solved one of environmental biology's greatest puzzles.
A team of researchers from IRCM (CEA-Jacob) and I2BC have shed light on the role of ComFC, a bacterial protein involved in natural transformation, itself a driving mechanism for the propagation of antibiotic resistance genes and virulence factors.
In an article published in Cell Reports, an international team including researchers from MIRCen showed that a cerebral network associated with highly elaborate cognitive capacities in humans differs from the comparable network in non-human primates.
A preclinical multimodal imaging study conducted by the Neurodegenerative Diseases Laboratory (LMN/MIRCen) and published in Human Molecular Genetics has shed light on cerebral alterations in Huntington's disease.
Working from 35,000 worldwide water and plankton samples collected by the Tara Oceans Expeditions and sequenced by Genoscope,, an international team of researchers has identified 5,500 new RNA virus species and met the challenge of their phylogenetic classification. The team's work was published in Science.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.