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LRIG Publications

Published on 2 July 2018
OGG1 competitive inhibitors show important off-target effects by directly inhibiting efflux pumps and disturbing mitotic progression.
Tanushi, X., Pinna, G., Vandamme, M., Siberchicot, S., D’Augustin, O., Di Guilmi, A.M., Radicella, J.P., Castaing, B., Smith, R., Huet, S., Leteurtre, F., Campalans, A.
OGG1 competitive inhibitors show important off-target effects by directly inhibiting efflux pumps and disturbing mitotic progression
Tanushi X., Pinna G., Vandamme M., Siberchicot C., D'Augustin O., Di Guilmi AM, Radicella JP., Castaing B., Smith R., Huet S., Leteurtre F.,  Campalans A.
Foetal exposure to the bisphenols BADGE and BPAF impairs meiosis through DNA oxidation in mouse ovaries
Abdallah, S., Jampy, A., Moison, D., Wieckowski, M., Messiaen, S., Martini, E., Campalans, A., Radicella, JP., Rouiller-Fabre, V., Livera, G., Guerquin, MJ
ComFC mediates transport and handling of single-stranded DNA during natural transformation
Prashant P Damke, Louisa Celma, Sumedha M Kondekar, Anne Marie Di Guilmi, Stéphanie Marsin, Jordane Dépagne, Xavier Veaute, Pierre Legrand, Hélène Walbott, Julien Vercruyssen, Raphaël Guérois, Sophie Quevillon-Cheruel, J Pablo Radicella
Tumor resistance to radiotherapy is triggered by an ATM/TAK1-dependent-increased expression of the cellular prion protein
Jacqueline Bernardino-Sgherri, Capucine Siberchicot, Frédéric Auvré, Didier Busso, Clémentine Brocas, Ghazi El Masri, Anna Lioutsko, Federica Ferri, J Pablo Radicella, Paul-Henri Romeo, Anne Bravard
A peptide of a type I toxin-antitoxin system induces Helicobacter pylori morphological transformation from spiral shape to coccoids
Lamya El Mortaji, Alejandro Tejada-Arranz, Aline Rifflet, Ivo G. Boneca, Gerard Pehau-Arnaudet, J. Pablo Radicella, Stephanie Marsin and Hilde De Reuse
Lost in the Crowd: How Does Human 8-Oxoguanine DNA Glycosylase 1 (OGG1) Find 8-Oxoguanine in the Genome?
Ostiane D'Augustin, Sébastien Huet, Anna Campalans, Juan Pablo Radicella 
Human hematopoietic stem/progenitor cells display reactive oxygen species-dependent long-term hematopoietic defects after exposure to low doses of ionizing radiations
Elia Henry, Inès Souissi-Sahraoui, Margaux Deynoux, Andréas Lefèvre, Vilma Barroca, Anna Campalans, Véronique Ménard, Julien Calvo, Françoise Pflumio, Marie-Laure Arcangeli
MasterPATH: network analysis of functional genomics screening data
Natalia Rubanova, Guillaume Pinna, Jeremie Kropp, Anna Campalans, Juan Pablo Radicella, Anna Polesskaya, Annick Harel-Bellan, Nadya Morozova
Chromatin recruitment of OGG1 requires cohesin and mediator and is essential for efficient 8-oxoG removal
Emilie Lebraud , Guillaume Pinna , Capucine Siberchicot , Jordane Depagne , Didier Busso , Damiano Fantini , Lamya Irbah , Elena Robeska , Gueorgui Kratassiouk , Jean-Luc Ravanat , Bernd Epe , J Pablo Radicella , Anna Campalans
Des mecanismes moleculaires Aux Applications Cliniques. L’essentiel Du Colloque Replication-Reparation-Recombinaison 2019
Lensless Microscopy Platform for Single Cell and Tissue Visualization
Ramona Corman, Willem Boutu, Anna Campalans, Pablo Radicella, Joana Duarte, Maria Kholodtsova, Laure Bally-Cuif, Nicolas Dray, Fabrice Harms, Guillaume Dovillaire, Samuel Bucourt, Hamed Merdji
Molecular Dissection of Helicobacter Pylori Topoisomerase I Reveals an Additional Active Site in the Carboxyl Terminus of the Enzyme
Sumedha M Kondekar, Gaurav V Gunjal, Juan Pablo Radicella, Desirazu N Rao
Identification of the periplasmic DNA receptor for natural transformation of Helicobacter pylori.
Damke PP, Di Guilmi AM, Fernández Varela P, Velours C, Marsin S, Veaute X, Machouri M, Gunjal GV, Rao DN, Charbonnier JB, Radicella JP.
Prion protein deficiency impairs hematopoietic stem cells determination and sensitizes myeloid progenitors to irradiation
Siberchicot C, Gault N, Déchamps N, Barroca V, Aguzzi A, Roméo PH, Radicella JP, Bravard A, Bernardino-Sgherri J.
Identification of an XRCC1 DNA binding activity essential for retention at sites of DNA damage
Mok MCY, Campalans A, Pillon MC, Guarné A, Radicella JP, Junop MS
The C-terminal domain of HpDprA is a DNA-binding Winged Helix domain that does not bind double-stranded DNA.
Lisboa J, Celma L, Sanchez D, Marquis M, Andreani J, Guérois R, Ochsenbein F, Durand D, Marsin S, Cuniasse P, Radicella JP, Quevillon-Cheruel .
Mitochondrial maintenance under oxidative stress depends on mitochondrially localised ?-OGG1.
Lia D, Reyes A, de Melo Campos JTA, Piolot T, Baijer J, Radicella JP, Campalans A.
The transcription-coupled DNA repair-initiating protein CSB promotes XRCC1 recruitment to oxidative DNA damage.
Menoni H, Wienholz F, Theil AF, Janssens RC, Lans H, Campalans A, Radicella JP, Marteijn JA, Vermeulen W.
Structural basis for the substrate selectivity of Helicobacter pylori NucT nuclease activity.
Celma L, Corbinais C, Vercruyssen J, Veaute X, de la Sierra-Gallay IL, Guerois R, Busso D, Mathieu A, Marsin S, Quevillon-Cheruel S, Radicella JP.
Incorporating interaction networks into the determination of functionally related hit genes in genomic experiments with Markov random fields.
Robinson S, Nevalainen J, Pinna G, Campalans A, Radicella JP, Guyon L
ComB proteins expression levels determine Helicobacter pylori competence capacity.
Corbinais C, Mathieu A, Damke PP, Kortulewski T, Busso D, Prado-Acosta M, Radicella JP, Marsin S.
A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis
Saintigny Y, Chevalier F, Bravard A, Dardillac E, Laurent D, Hem S, Depagne J, Radicella JP2, Lopez BS
Following transforming DNA in Helicobacter pylori from uptake to expression
Corbinais C, Mathieu A, Kortulewski T, Radicella JP, Marsin S
Mutations in the nucleotide binding and hydrolysis domains of Helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function
Damke PP, Dhanaraju R, Marsin S, Radicella JP, Rao DN
XPC deficiency is related to APE1 and OGG1 expression and function
de Melo JT, de Souza Timoteo AR, Lajus TB, Brandão JA, de Souza-Pinto NC, Menck CF, Campalans A, Radicella JP, Vessoni AT, Muotri AR,Agnez-Lima LF
E2F1 and E2F2 induction in response to DNA damage preserves genomic stability in neuronal cells.
Castillo DS, Campalans A, Belluscio LM, Carcagno AL, Radicella JP, Cánepa ET, Pregi N
Interaction with OGG1 is required for efficient recruitment of XRCC1 to base excision repair and maintenance of genetic stability after exposure to oxidative stress
Campalans A, Moritz E, Kortulewski T, Biard D, Epe B, Radicella JP
Phi-score: A cell-to-cell phenotypic scoring method for sensitive and selective hit discovery in cell-based assays.
Guyon L, Lajaunie C, Fer F, Bhajun R, Sulpice E, Pinna G, Campalans A, Radicella JP, Rouillier P, Mary M,Combe S, Obeid P, Vert JP, Gidrol X
The nuclease activities of both the Smr domain and an additional LDLK motif are required for an efficient anti-recombination function of Helicobacter pylori?MutS2
Damke PP, Dhanaraju R, Marsin S, Radicella JP, Rao DN
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